PSA5B_ARATH - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: PSA5B_ARATH
• UniProt AC: Q42134
• Protein Name: Proteasome subunit alpha type-5-B
• Gene Name: PAE2
• Organism: Arabidopsis thaliana (Mouse-ear cress).
• Sequence Length: 237
• Subcellular Localization: Cytoplasm. Nucleus.
• Protein Description: The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity..
• Protein Sequence: MFLTRTEYDRGVNTFSPEGRLFQVEYAIEAIKLGSTAIGVKTKEGVVLAVEKRITSPLLEPSSVEKIMEIDDHIGCAMSGLIADARTLVEHARVETQNHRFSYGEPMTVESTTQALCDLALRFGEGEEESMSRPFGVSLLIAGHDENGPSLYYTDPSGTFWQCNAKAIGSGSEGADSSLQEQFNKDITLQEAETIAVSILKQVMEEKVTPNNVDIAKVAPAYHLYTPQEVEAVISRL

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
1	Acetylation	-------MFLTRTEY -------CCCCCCCC	5.84	20516081
16	Phosphorylation	DRGVNTFSPEGRLFQ CCCCCCCCCCCCEEE	21.72	29654922
66	Ubiquitination	LEPSSVEKIMEIDDH CCCCHHHHHHHHCCH	45.24	20516081
185	Ubiquitination	SLQEQFNKDITLQEA HHHHHHCCCCCHHHH	52.36	20516081

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of PSA5B_ARATH !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of PSA5B_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of PSA5B_ARATH !!

Protein-Protein Interaction

Oops, there are no PPI records of PSA5B_ARATH !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.