PS10A_ARATH - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: PS10A_ARATH
• UniProt AC: Q9SEI3
• Protein Name: 26S proteasome regulatory subunit 10B homolog A
• Gene Name: RPT4A
• Organism: Arabidopsis thaliana (Mouse-ear cress).
• Sequence Length: 399
• Subcellular Localization: Cytoplasm. Nucleus.
• Protein Description: The 26S proteasome is involved in the ATP-dependent degradation of ubiquitinated proteins. The regulatory (or ATPase) complex confers ATP dependency and substrate specificity to the 26S complex..
• Protein Sequence: MTDVDESVRRRTAAVSEYRKKLLQHKELESRVRTARENLRGAKKEFNKTEDDLKSLQSVGQIIGEVLRPLDNERLIVKASSGPRYVVGCRSKVDKEKLTSGTRVVLDMTTLTIMRALPREVDPVVYNMLHEDPGNISYSAVGGLGDQIRELRESIELPLMNPELFLRVGIKPPKGVLLYGPPGTGKTLLARAIASNIDANFLKVVSSAIIDKYIGESARLIREMFNYAREHQPCIIFMDEIDAIGGRRFSEGTSADREIQRTLMELLNQLDGFDNLGKVKMIMATNRPDVLDPALLRPGRLDRKIEIPLPNEQSRMDILKIHAAGIAKHGEIDYEAIVKLAEGFNGADLRNICTEAGMFAIRAERDYVIHEDFMKAVRKLSEAKKLESSSHYNADFGKE

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
2	Acetylation	------MTDVDESVR ------CCCHHHHHH	44.74	22223895
80	Phosphorylation	ERLIVKASSGPRYVV CEEEEECCCCCEEEE	30.06	19880383
203	Ubiquitination	NIDANFLKVVSSAII CCCHHHHHHHHHHHH	36.13	20516081

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of PS10A_ARATH !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of PS10A_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of PS10A_ARATH !!

Protein-Protein Interaction

Oops, there are no PPI records of PS10A_ARATH !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.