dbPTM

PRX2F_ARATH - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	PRX2F_ARATH
UniProt AC	Q9M7T0
Protein Name	Peroxiredoxin-2F, mitochondrial
Gene Name	PRXIIF
Organism	Arabidopsis thaliana (Mouse-ear cress).
Sequence Length	201
Subcellular Localization	Mitochondrion matrix .
Protein Description	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides. Reduces preferentially hydrogen peroxide rather than alkyl peroxides. May be involved in mitochondrial redox homeostasis..
Protein Sequence	MAMSILKLRNLSALRSAANSARIGVSSRGFSKLAEGTDITSAAPGVSLQKARSWDEGVSSKFSTTPLSDIFKGKKVVIFGLPGAYTGVCSQQHVPSYKSHIDKFKAKGIDSVICVSVNDPFAINGWAEKLGAKDAIEFYGDFDGKFHKSLGLDKDLSAALLGPRSERWSAYVEDGKVKAVNVEEAPSDFKVTGAEVILGQI

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
37	Phosphorylation	FSKLAEGTDITSAAP HHHHCCCCCCCCCCC	18.74	22092075
53	Phosphorylation	VSLQKARSWDEGVSS CCHHHCCCCCCCCCC	43.68	27545962
86	Phosphorylation	FGLPGAYTGVCSQQH EECCCCCCCCCCCCC	23.70	22092075
139	Phosphorylation	AKDAIEFYGDFDGKF CCHHEEHHCCCCCCC	11.73	19880383
149	Phosphorylation	FDGKFHKSLGLDKDL CCCCCHHHCCCCCCH	21.06	22092075

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of PRX2F_ARATH !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of PRX2F_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of PRX2F_ARATH !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
Oops, there are no PPI records of PRX2F_ARATH !!

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of PRX2F_ARATH

Related Literatures of Post-Translational Modification