PRSR3_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: PRSR3_HUMAN
• UniProt AC: Q2NL68
• Protein Name: Proline and serine-rich protein 3
• Gene Name: PROSER3
• Organism: Homo sapiens (Human).
• Sequence Length: 480
• Protein Sequence: MDRSLPVFSIQDSPFGDAPLGRSHYWPSQSQTWCPKTLSPSRSQRSRLPQAPKALATGPNSPELFEESWPSSSGTPSLPSTTEGQMWASPAPTLIDSGDSVVAKYINRFRQAQPTSREERQPAGPTPADFWWLQSDSPDPSSQSAAAGANKPEGRPHTAVPTAVNVTSASHAVAPLQEIKQNLHTWNSSLLDLETLSLQSRAARLLKRSKASISSSSSLSPSDASTSSFPTSSDGLSPFSETFIPDSSKGLGPRAPASPAPAQAQTPTPAPAPASSQAPLRPEDDILYQWRQRRKLEQAQGSKGDRAWVPPLTPALRTLAESLKAKALPPAAGSVIRKSEATPSPGACLQPEVPLSPAEQATTVKASPPAFQVGSPEALAPPPPAADHAPSEALLAQAALLLQAAEDSDGSEFQDDPVLQVLRAHRAELSRQKREADARLSFLLDQAEDLGSWSPPAGSPPRSPRRLLRREGDSLEARRL

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
13	Phosphorylation	PVFSIQDSPFGDAPL CEEEECCCCCCCCCC		22199227
25	Phosphorylation	APLGRSHYWPSQSQT CCCCCCCCCCCCCCC		21552520
32	Phosphorylation	YWPSQSQTWCPKTLS CCCCCCCCCCCCCCC		-
167	O-linked_Glycosylation	VPTAVNVTSASHAVA CCCEEECCCCCCCCC		28411811
258	Phosphorylation	LGPRAPASPAPAQAQ CCCCCCCCCCCCCCC		28348404
313	Phosphorylation	RAWVPPLTPALRTLA CCCCCCCCHHHHHHH		-
339	Phosphorylation	AGSVIRKSEATPSPG CCCCCCCCCCCCCCC		26552605
342	Phosphorylation	VIRKSEATPSPGACL CCCCCCCCCCCCCCC		25627689
344	Phosphorylation	RKSEATPSPGACLQP CCCCCCCCCCCCCCC		25159151
356	Phosphorylation	LQPEVPLSPAEQATT CCCCCCCCHHHHCCC		25159151
362	Phosphorylation	LSPAEQATTVKASPP CCHHHHCCCCCCCCC		28450419
363	Phosphorylation	SPAEQATTVKASPPA CHHHHCCCCCCCCCC		28450419
408	Phosphorylation	LLQAAEDSDGSEFQD HHHHHHCCCCCCCCC		-
441	Phosphorylation	READARLSFLLDQAE HHHHHHHHHHHHHHH		27080861
452	Phosphorylation	DQAEDLGSWSPPAGS HHHHHHCCCCCCCCC		28450419
454	Phosphorylation	AEDLGSWSPPAGSPP HHHHCCCCCCCCCCC		27422710
459	Phosphorylation	SWSPPAGSPPRSPRR CCCCCCCCCCCCHHH		22617229
463	Phosphorylation	PAGSPPRSPRRLLRR CCCCCCCCHHHHHHH		22617229
474	Phosphorylation	LLRREGDSLEARRL- HHHHCCCCCHHHCC-		24719451

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of PRSR3_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of PRSR3_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of PRSR3_HUMAN !!

Protein-Protein Interaction

Oops, there are no PPI records of PRSR3_HUMAN !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.