dbPTM

PRS6B_ARATH - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	PRS6B_ARATH
UniProt AC	Q9SEI4
Protein Name	26S proteasome regulatory subunit 6B homolog
Gene Name	RPT3
Organism	Arabidopsis thaliana (Mouse-ear cress).
Sequence Length	408
Subcellular Localization	Cytoplasm. Nucleus.
Protein Description	The 26S proteasome is involved in the ATP-dependent degradation of ubiquitinated proteins. The regulatory (or ATPase) complex confers ATP dependency and substrate specificity to the 26S complex..
Protein Sequence	MASAAVASMVLDPKASPALMDLSTADEEDLYGRLKSLERQLEFTDIQEEYVKDEQKNLKRELLRAQEEVKRIQSVPLVIGQFMEMVDQNNGIVGSTTGSNYYVRILSTINRELLKPSASVALHRHSNALVDVLPPEADSSISLLSQSEKPDVSYNDIGGCDIQKQEIREAVELPLTHHELYKQIGIDPPRGVLLYGPPGTGKTMLAKAVANHTTAAFIRVVGSEFVQKYLGEGPRMVRDVFRLAKENAPAIIFIDEVDAIATARFDAQTGADREVQRILMELLNQMDGFDQTVNVKVIMATNRADTLDPALLRPGRLDRKIEFPLPDRRQKRLVFQVCTSKMNLSDEVDLEDYVSRPDKISAAEIAAICQEAGMHAVRKNRYVILPKDFEKGYRANVKKPDTDFEFYK

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
2	Acetylation	------MASAAVASM ------CCCHHHHHH	14.10	22223895
16	Phosphorylation	MVLDPKASPALMDLS HHHCCCCCHHHCCCC	19.48	30291188
20	Sulfoxidation	PKASPALMDLSTADE CCCCHHHCCCCCCCH	5.45	23289948
23	Phosphorylation	SPALMDLSTADEEDL CHHHCCCCCCCHHHH	19.79	23776212
24	Phosphorylation	PALMDLSTADEEDLY HHHCCCCCCCHHHHH	45.48	23776212
107	Phosphorylation	NYYVRILSTINRELL HHHHEEHHHCCHHHH	25.52	29654922
214	Phosphorylation	KAVANHTTAAFIRVV HHHHCCCHHHHHHHH	14.40	19880383

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of PRS6B_ARATH !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of PRS6B_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of PRS6B_ARATH !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
Oops, there are no PPI records of PRS6B_ARATH !!

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of PRS6B_ARATH

Related Literatures of Post-Translational Modification