PRRX1_MOUSE - dbPTM
PRRX1_MOUSE - PTM Information in dbPTM
Basic Information of Protein
UniProt ID PRRX1_MOUSE
UniProt AC P63013
Protein Name Paired mesoderm homeobox protein 1
Gene Name Prrx1
Organism Mus musculus (Mouse).
Sequence Length 245
Subcellular Localization Nucleus.
Protein Description Acts as a transcriptional regulator of muscle creatine kinase (MCK) and so has a role in the establishment of diverse mesodermal muscle types. The protein binds to an A/T-rich element in the muscle creatine enhancer..
Protein Sequence MTSSYGHVLERQPALGGRLDSPGNLDTLQAKKNFSVSHLLDLEEAGDMVAAQADESVGEAGRSLLESPGLTSGSDTPQQDNDQLNSEEKKKRKQRRNRTTFNSSQLQALERVFERTHYPDAFVREDLARRVNLTEARVQVWFQNRRAKFRRNERAMLANKNASLLKSYSGDVTAVEQPIVPRPAPRPTDYLSWGTASPYSAMATYSATCANNSPAQGINMANSIANLRLKAKEYSLQRNQVPTVN
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
2Phosphorylation------MTSSYGHVL
------CCCCCCCHH		26.7829514104
3Phosphorylation-----MTSSYGHVLE
-----CCCCCCCHHC		21.9229514104
4Phosphorylation----MTSSYGHVLER
----CCCCCCCHHCC		26.4329514104
5Phosphorylation---MTSSYGHVLERQ
---CCCCCCCHHCCC		15.8329514104
21PhosphorylationALGGRLDSPGNLDTL
CCCCCCCCCCCHHHH		39.0226824392
27PhosphorylationDSPGNLDTLQAKKNF
CCCCCHHHHHHHCCC		24.7629514104
63PhosphorylationSVGEAGRSLLESPGL
CHHHHHHHHHHCCCC		36.0725619855
67PhosphorylationAGRSLLESPGLTSGS
HHHHHHHCCCCCCCC		25.0025619855
71PhosphorylationLLESPGLTSGSDTPQ
HHHCCCCCCCCCCCC		36.6425619855
72PhosphorylationLESPGLTSGSDTPQQ
HHCCCCCCCCCCCCC		41.1425619855
74PhosphorylationSPGLTSGSDTPQQDN
CCCCCCCCCCCCCCH		37.7725619855
76PhosphorylationGLTSGSDTPQQDNDQ
CCCCCCCCCCCCHHC		25.3725619855
86PhosphorylationQDNDQLNSEEKKKRK
CCHHCCCHHHHHHHH		56.5825619855
100PhosphorylationKQRRNRTTFNSSQLQ
HHHHHHHCCCHHHHH		19.9929514104
103PhosphorylationRNRTTFNSSQLQALE
HHHHCCCHHHHHHHH		18.4429514104
104PhosphorylationNRTTFNSSQLQALER
HHHCCCHHHHHHHHH		35.6929514104
160AcetylationERAMLANKNASLLKS
HHHHHHHCCHHHHHH		48.5623806337
169PhosphorylationASLLKSYSGDVTAVE
HHHHHHCCCCCEEEE		35.2926370283
190 (in isoform 2)Phosphorylation-12.7125777480
192 (in isoform 2)Phosphorylation-19.7525777480
195 (in isoform 2)Phosphorylation-20.0826160508
197PhosphorylationYLSWGTASPYSAMAT
CCCCCCCCCCCCCEE		24.98-
197 (in isoform 2)Phosphorylation-24.9826160508
199 (in isoform 2)Phosphorylation-13.4326160508
234PhosphorylationLRLKAKEYSLQRNQV
HHHHHHHHHCHHCCC		17.6129514104
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of PRRX1_MOUSE !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of PRRX1_MOUSE !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of PRRX1_MOUSE !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions

Oops, there are no PPI records of PRRX1_MOUSE !!
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of PRRX1_MOUSE

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Related Literatures of Post-Translational Modification

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