PROM2_MOUSE - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: PROM2_MOUSE
• UniProt AC: Q3UUY6
• Protein Name: Prominin-2
• Gene Name: Prom2
• Organism: Mus musculus (Mouse).
• Sequence Length: 835
• Subcellular Localization: Apical cell membrane; Multi-pass membrane protein. Basolateral cell membrane; Multi-pass membrane protein. Cell projection, microvillus membrane; Multi-pass membrane protein. Cell projection, cilium membrane; Multi-pass membrane protein. Colocalizes
• Protein Sequence: MTRSPGLMVPLLGLSLGLALSLPEAVTDDCGSLGRVEHLAFARVPRTRELAPLVRASGPLNSLYGTVRRFLSVVQLNPFPAELIKTLLNDPSSVKTDEVVRYEAGYVVCAVIAGLYLLLVPITGLCFCCCRCRQRCGGRVKTEHKAMACERGTLMIFLLLTTLVLLIGMVCAFATNQHTHSQTGPSVKAVPETLLSLRGLVSDVPEELRAIAEQFSVPQKQVSKELDGVGENLGNVIHNRLKSTVYPVLASVHSLGQALQVSIDHLRALNTTSVELQEAQRHLEPPVQAHRERLLALLQDSWCHEENCKRVLSQAGALQLGADFSQTPPVDDVLHRLKDVPETNFSSMVQEEKATFNNLPLLVQVQAVSVVKDVKKALAEQPEGLRMLAQAFPGSEAASRWSQALEGLEQRSRPYLQEVQQYETYRWILGCVLCSAILLVVICNLLGLSLGIWGLFAREDPSHSETKGEAGARLLMAGVAFSFLFAVPLILLVFVTFLVGGNVQTLVCRSWESGELYEFADTPGNLPPSMNLSYLLGLKKNISIVQAYRQCKAGAVLWKVLQLNDSYDLDKHLDIKQYTHKIQQELQSFQVDLKELDLLSPTARQDLEALQRSGLEKIHYRGFLVQIQKPVVNTDMWQLAQELEGLAQAQNDSLLRQQLREEARELRSLYQEKVVPQESLVTKLNFSVKTLESLAPSLQVNTSDFLDSVTRLKGELPVQINHILRNATECFLTREMGYFSQYVTWVRAEVTQRIATCQPFSTALDNGHVILCDMMADPWNAFWFCLGWCTFFLIPSIIFAVKTSKYFRPIRKRLSSTSSEETQLFHIPRVTSLKL

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
62	Phosphorylation	RASGPLNSLYGTVRR HHCCCHHHHHHHHHH	30.56	21454597
66	Phosphorylation	PLNSLYGTVRRFLSV CHHHHHHHHHHHHHH	9.40	21454597
270	N-linked_Glycosylation	IDHLRALNTTSVELQ HHHHHHHCCCCHHHH	40.08	-
679	Phosphorylation	EKVVPQESLVTKLNF HCCCCHHHHHHHCCC	23.92	-
815	Phosphorylation	RPIRKRLSSTSSEET HHHHHHHCCCCCCCH	35.29	26239621
816	Phosphorylation	PIRKRLSSTSSEETQ HHHHHHCCCCCCCHH	36.58	26239621
817	Phosphorylation	IRKRLSSTSSEETQL HHHHHCCCCCCCHHC	32.66	26239621
818	Phosphorylation	RKRLSSTSSEETQLF HHHHCCCCCCCHHCC	37.39	26239621
819	Phosphorylation	KRLSSTSSEETQLFH HHHCCCCCCCHHCCC	39.27	26239621
822	Phosphorylation	SSTSSEETQLFHIPR CCCCCCCHHCCCCCC	26.90	26239621

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of PROM2_MOUSE !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of PROM2_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of PROM2_MOUSE !!

Protein-Protein Interaction

Oops, there are no PPI records of PROM2_MOUSE !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.