PRI2_MOUSE - dbPTM
PRI2_MOUSE - PTM Information in dbPTM
Basic Information of Protein
UniProt ID PRI2_MOUSE
UniProt AC P33610
Protein Name DNA primase large subunit
Gene Name Prim2
Organism Mus musculus (Mouse).
Sequence Length 505
Subcellular Localization
Protein Description DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments made during discontinuous DNA replication..
Protein Sequence MQFSGRIRKKLRLAGDQRNASYPHSLQFYLQPPTENISLTEFENLAFDRVKLLKAIENLGVSYVKGTEQYQSKLEAEIRKLKFSYRENLEDEYEPRRRDHISHFILRLAYCQSEDLRRWFIQQEMDLLRFRFSILPKDKVQSFLKDSHLHFEAISDEEKTLREQDIMASSPSLSGIKLESESVYKVPFADALDLFRGRKVYLEDGFAYVPLKDIVAIILNEFRATLSKALALTARSLPAVQSDERLQPLLNHLSHSYTGQDYSTQKNTGKISLDQIDSLSTKSFPPCMRQLHKALRENHHLRHGGRMQYGLFLKGIGLTLEQALQFWKQEFIRGKMDPDKFDKGYSYNIRHSFGKEGKRTDYTPFSCMKIILTNPPGQGDYHGCPFRHSDAELLKQKMQSYKIPASGISQILDLVKGNHYQVACQKYFEMTHNVDDCGFSLNHPNQFFFESQRILTGGKDIKKEISQPETPQHKPSTQKTRDAASALASLDSSLEMDLEGLEEYF
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
155PhosphorylationHLHFEAISDEEKTLR
CCCEEECCCHHHHHH		46.1226525534
172PhosphorylationDIMASSPSLSGIKLE
HHHHCCCCCCCCEEC		36.8026239621
174PhosphorylationMASSPSLSGIKLESE
HHCCCCCCCCEECCC		42.6926239621
272PhosphorylationQKNTGKISLDQIDSL
CCCCCCCCHHHHHHC		29.4026824392
345PhosphorylationPDKFDKGYSYNIRHS
HHHCCCCCCCCCCCC		17.4529514104
381PhosphorylationNPPGQGDYHGCPFRH
CCCCCCCCCCCCCCC		13.61-
384GlutathionylationGQGDYHGCPFRHSDA
CCCCCCCCCCCCCCH		1.5124333276
466PhosphorylationKDIKKEISQPETPQH
CCHHHHHCCCCCCCC		40.5528066266
470PhosphorylationKEISQPETPQHKPST
HHHCCCCCCCCCCCC		34.6328418008
476PhosphorylationETPQHKPSTQKTRDA
CCCCCCCCCHHHHHH		48.5528066266
477PhosphorylationTPQHKPSTQKTRDAA
CCCCCCCCHHHHHHH		42.4828066266
485PhosphorylationQKTRDAASALASLDS
HHHHHHHHHHHHCCH		26.0729550500
489PhosphorylationDAASALASLDSSLEM
HHHHHHHHCCHHHCC		33.2929550500
492PhosphorylationSALASLDSSLEMDLE
HHHHHCCHHHCCCCC		41.9629550500
493PhosphorylationALASLDSSLEMDLEG
HHHHCCHHHCCCCCH		28.1929550500
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of PRI2_MOUSE !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of PRI2_MOUSE !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of PRI2_MOUSE !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions

Oops, there are no PPI records of PRI2_MOUSE !!
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of PRI2_MOUSE

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Related Literatures of Post-Translational Modification

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