PRI1_MOUSE - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: PRI1_MOUSE
• UniProt AC: P20664
• Protein Name: DNA primase small subunit
• Gene Name: Prim1
• Organism: Mus musculus (Mouse).
• Sequence Length: 417
• Protein Description: DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments made during discontinuous DNA replication..
• Protein Sequence: MEPFDPAELPELLKLYYRRLFPYAQYYRWLNYGGVTKNYFQHREFSFTLKDDIYIRYQSFNNQSELEKEMQKMNPYKIDIGAVYSHRPNQHNTVKLGAFQAQEKELVFDIDMTDYDDVRRCCSSADICSKCWTLMTMAMRIIDRALKEDFGFKHRLWVYSGRRGVHCWVCDESVRKLSSAVRSGIVEYLSLVKGGQDVKKKVHLNEKVHPFVRKSINIIKKYFEEYALVGQDILENKENWDKILALVPETIHDELQRGFQKFHSSPQRWEHLRKVANSSQNMKNDKCGPWLEWEVMLQYCFPRLDVNVSKGVNHLLKSPFSVHPKTGRISVPIDFHKVDQFDPFTVPTISAICRELDMVSTHEKEKEENEADSKHRVRGYKKTSLAPYVKVFEQFLENLDKSRKGELLKKSDLQKDF

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
1	Acetylation	-------MEPFDPAE -------CCCCCHHH	15.47	-
179	Phosphorylation	ESVRKLSSAVRSGIV HHHHHHHHHHHHCHH	41.02	-
318	Phosphorylation	GVNHLLKSPFSVHPK HHHHHHCCCCCCCCC	31.02	-
321	Phosphorylation	HLLKSPFSVHPKTGR HHHCCCCCCCCCCCC	23.93	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of PRI1_MOUSE !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of PRI1_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of PRI1_MOUSE !!

Protein-Protein Interaction

Oops, there are no PPI records of PRI1_MOUSE !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.