| UniProt ID | PRDM7_HUMAN | |
|---|---|---|
| UniProt AC | Q9NQW5 | |
| Protein Name | Probable histone-lysine N-methyltransferase PRDM7 | |
| Gene Name | PRDM7 | |
| Organism | Homo sapiens (Human). | |
| Sequence Length | 492 | |
| Subcellular Localization | Nucleus . Chromosome . | |
| Protein Description | Probable histone methyltransferase.. | |
| Protein Sequence | MSPERSQEESPEGDTERTERKPMVKDAFKDISIYFTKEEWAEMGDWEKTRYRNVKMNYNALITVGLRATRPAFMCHRRQAIKLQVDDTEDSDEEWTPRQQVKPPWMAFRGEQSKHQKGMPKASFNNESSLRELSGTPNLLNTSDSEQAQKPVSPPGEASTSGQHSRLKLELRRKETEGKMYSLRERKGHAYKEISEPQDDDYLYCEMCQNFFIDSCAAHGPPTFVKDSAVDKGHPNRSALSLPPGLRIGPSGIPQAGLGVWNEASDLPLGLHFGPYEGRITEDEEAANSGYSWLITKGRNCYEYVDGKDKSSANWMRYVNCARDDEEQNLVAFQYHRQIFYRTCRVIRPGCELLVWSGDEYGQELGIRSSIEPAESLGQAVNCWSGMGMSMARNWASSGAASGRKSSWQGENQSQRSIHVPHAVWPFQVKNFSVNMWNAITPLRTSQDHLQENFSNQRIPAQGIRIRSGNILIHAAVMTKPKVKRSKKGPNS | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 21 | Ubiquitination | DTERTERKPMVKDAF CCCCCCCCHHHHHHH | 31.09 | - | |
| 25 | Ubiquitination | TERKPMVKDAFKDIS CCCCHHHHHHHHHCE | 36.77 | - | |
| 29 | Ubiquitination | PMVKDAFKDISIYFT HHHHHHHHHCEEEEE | 56.74 | - | |
| 36 | Phosphorylation | KDISIYFTKEEWAEM HHCEEEEEHHHHHHC | 22.15 | 29759185 | |
| 69 | Phosphorylation | ITVGLRATRPAFMCH EEEECCCCCCHHHHC | 30.65 | - | |
| 102 | Sumoylation | WTPRQQVKPPWMAFR CCCHHHCCCCCCCCC | 40.81 | - | |
| 105 (in isoform 2) | Phosphorylation | - | 10.16 | 27251275 | |
| 106 (in isoform 2) | Phosphorylation | - | 2.89 | 27251275 | |
| 112 (in isoform 2) | Phosphorylation | - | 61.68 | 27251275 | |
| 118 (in isoform 2) | Phosphorylation | - | 30.93 | - | |
| 124 (in isoform 2) | Phosphorylation | - | 15.82 | 27251275 | |
| 129 (in isoform 2) | Phosphorylation | - | 25.85 | 27251275 | |
| 143 (in isoform 2) | Phosphorylation | - | 37.76 | - | |
| 176 | Phosphorylation | LELRRKETEGKMYSL EEEEEHHCCCCEEEH | 53.74 | - | |
| 181 | Phosphorylation | KETEGKMYSLRERKG HHCCCCEEEHHHHCC | 14.19 | - | |
| 182 | Phosphorylation | ETEGKMYSLRERKGH HCCCCEEEHHHHCCC | 19.90 | 24719451 | |
| 191 | Phosphorylation | RERKGHAYKEISEPQ HHHCCCCCCCCCCCC | 11.95 | - | |
| 468 | Phosphorylation | AQGIRIRSGNILIHA CCCEEECCCCEEEEE | 33.54 | 23909892 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of PRDM7_HUMAN !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of PRDM7_HUMAN !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of PRDM7_HUMAN !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
Oops, there are no PPI records of PRDM7_HUMAN !! | ||||
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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