dbPTM

PRC2A_MOUSE - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	PRC2A_MOUSE
UniProt AC	Q7TSC1
Protein Name	Protein PRRC2A
Gene Name	Prrc2a
Organism	Mus musculus (Mouse).
Sequence Length	2158
Subcellular Localization	Cytoplasm. Nucleus.
Protein Description	May play a role in the regulation of pre-mRNA splicing..
Protein Sequence	MSDRSGPTAKGKDGKKYSSLNLFDTYKGKSLEIQKPAVAPRHGLQSLGKVAIARRMPPPANLPSLKAENKGNDPNVSLVPKDGTGWASKQEQSDPKSSDASTAQPPESQPLPASQTPASNQPKRPPTAPENTPSVPSGVKSWAQASVTHGAHGDGGRASNLLSRFSREEFPTLQAAGDQDKAAKERESAEQSSGPGPSLRPQNSTTWRDGGGRGPDDLEGPDSKLHHGHDPRGGLQPSGPPQFPPYRGMMPPFMYPPYLPFPPPYGPQGPYRYPTPDGPSRFPRVAGPRGSGPPMRLVEPVGRPSILKEDNLKEFDQLDQENDDGWAGAHEEVDYTEKLKFSDEEDGRDSDEEGAEGHKDSQSAAAEEPETDGKKGTSPGSELPPPKTAWTENARPSETEPAPPTPKPPPPPPHRGPVGNWGPPGDYPDRGGPPCKPPAPEDEDEAWRQRRKQSSSEISLAVERARRRREEEERRMQEERRAACAEKLKRLDEKFGAPDKRLKAEPAAPPVTPAAPALPPVVPKEIPAAPALPPTPTPTPEKEPEEPAQAPPVQAAPSPGVAPVPTLVSGGGCTANSNSSGSFEASPVEPQLPSKEGPEPPEEVPPPTTPPAPKMEPKGDGVGSTRQPPSQGLGYPKYQKSLPPRFQRQQQEQLLKQQQQQQQWQQQQQGTAPPAPVPPSPPQPVTLGAVPAPQAPPPPPKALYPGALGRPPPMPPMNFDPRWMMIPPYVDPRLLQGRPPLDFYPPGVHPSGLVPRERSDSGGSSSEPFERHAPPLLRERGTPPVDPKLAWVGDVFTTTPTDPRPLTSPLRQAADEEEKSMRSETPPVPPPPPYLANYPGFPENGTPGPPISRFPLEESAPPGPRPLPWPPGNDEAAKMQAPPPKKEPSKEEPPQLSGPEAGRKPARGGQGPPPPRRENRTETRWGPRPGSCRRGIPPEEPGVPPRRAGPIKKPPPPVKVEELPPKSLEQGDETPKVPKPDALKTAKGKVGPKETPPGGNLSPAPRLRRDYSYERVGPTSCRGRGRGEYFARGRGFRGTYGGRGRGARSREFRSYREFRGDDGRGGGSGGTNHPSAPRGRTASETRSEGSEYEEIPKRRRQRGSETGSETHESDLAPSDKEAPPPKEGVLGQVPLAPPQPGAPPSPAPARFSTARGGRVFTPRGVPSRRGRGGGRPPPVCSGWSPPAKSLVPKKPPTGPLPPSKEPLKEKLISGPLSPMSRAGNMGVGMEDGERPRRRRHGRAQQQDKPPRFRRLKQERENAARGADGKPPSLTLAASTPGPEETLTAATVPPPPRRTAAKSPDLSNQNSDQANEEWETASESSDFASERRGDKETPPAALMTSKAVGTPGANAGGAGPGISAMSRGDLSQRAKDLSKRSFSSQRPGMDRQNRRPGTGGKTGSGGGSSGGGGAGPGGRTGPGRGDKRSWPSPKNRSRPPEERPPGLPLPPPPPSSSAVFRLDQVIHSNPAGIQQALAQLSSRQGNVTAPGGHPRPKPGPPQAPQGSSPRPPTRYDPPRASSAISSDPHFEEPGPMVRGVGGTPRDSAGVNPFPPKRRERPPRKPELLQEETVPASHSSGFLGSKPEVPGPQEESRDSGTEALTPHIWNRLHTATSRKSYQPGSIEPWMEPLSPFEDVAGTEMSQSDSGVDLSGDSQVSSGPCSQRSSPDGGLKGSAEGPPKRPGGPSPLNAVPGESASGSEPSEPPRRRPPASHEGERKELPREQPLPPGPIGTERSQRTDRGPEPGPLRPAHRPGSQVEFGTTNKDSDLCLVVGDTLKGEKELVASATEAVPISRDWELLPSASTSAEPQPKSLGSGQCVPEPSPSGQRPYPEVFYGSPGPPNSQQVSGGAPIDSQLHPNSGGFRPGTPSLHQYRSQPLYLPPGPAPPSALLSGVALKGQFLDFSALQATELGKLPAGGVLYPPPSFLYSAAFCPSPLPDPPLLQVRQDLPSPSDFYSTPLQPGGQSGFLPSGAPAQQMLLPVVDSQLPVVNFGSLPPAPPPAPPPLSLLPVGPALQPPNLAVRPPPAPAARVLPSPARPFAPSLGRAELHPVELKPFQDYRKLSSNLGGPGSSRTPPSGRPFSGLNSRLKAPPSTYSGVFRTQRIDLYQQASPPDALRWMPKPWERAGPPSREGPPRRAEEPGSRGEKEPGLPPPR

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
18	Phosphorylation	GKDGKKYSSLNLFDT CCCCCEECCCCCEEC	36.91	26643407
19	Phosphorylation	KDGKKYSSLNLFDTY CCCCEECCCCCEECC	20.42	26643407
25	Phosphorylation	SSLNLFDTYKGKSLE CCCCCEECCCCCEEE	21.57	23984901
26	Phosphorylation	SLNLFDTYKGKSLEI CCCCEECCCCCEEEE	21.42	22817900
27	Acetylation	LNLFDTYKGKSLEIQ CCCEECCCCCEEEEC	63.05	22826441
29	Acetylation	LFDTYKGKSLEIQKP CEECCCCCEEEECCC	47.95	23806337
30	Phosphorylation	FDTYKGKSLEIQKPA EECCCCCEEEECCCC	39.64	29514104
35	Acetylation	GKSLEIQKPAVAPRH CCEEEECCCCCCCCC	40.37	23806337
46	Phosphorylation	APRHGLQSLGKVAIA CCCCCHHHHHHHHHH	44.10	18846507
127	Phosphorylation	NQPKRPPTAPENTPS CCCCCCCCCCCCCCC	58.49	25293948
132	Phosphorylation	PPTAPENTPSVPSGV CCCCCCCCCCCCCCH	18.45	28066266
134	Phosphorylation	TAPENTPSVPSGVKS CCCCCCCCCCCCHHH	44.62	28066266
146	Phosphorylation	VKSWAQASVTHGAHG HHHHEECHHCCCCCC	18.57	29899451
159	Phosphorylation	HGDGGRASNLLSRFS CCCCCHHHHHHHHHC	27.01	25266776
163	Phosphorylation	GRASNLLSRFSREEF CHHHHHHHHHCHHHC	34.15	25266776
166	Phosphorylation	SNLLSRFSREEFPTL HHHHHHHCHHHCCCH	37.36	28725479
172	Phosphorylation	FSREEFPTLQAAGDQ HCHHHCCCHHHHCCH	36.50	25159016
204	Phosphorylation	PSLRPQNSTTWRDGG CCCCCCCCCCCCCCC	23.20	25293948
205	Phosphorylation	SLRPQNSTTWRDGGG CCCCCCCCCCCCCCC	37.62	25293948
206	Phosphorylation	LRPQNSTTWRDGGGR CCCCCCCCCCCCCCC	20.51	25293948
272	Asymmetric dimethylarginine	YGPQGPYRYPTPDGP CCCCCCCCCCCCCCC	33.80	-
272	Methylation	YGPQGPYRYPTPDGP CCCCCCCCCCCCCCC	33.80	-
273	Phosphorylation	GPQGPYRYPTPDGPS CCCCCCCCCCCCCCC	12.96	22817900
281	Dimethylation	PTPDGPSRFPRVAGP CCCCCCCCCCCCCCC	49.04	-
281	Methylation	PTPDGPSRFPRVAGP CCCCCCCCCCCCCCC	49.04	-
284	Dimethylation	DGPSRFPRVAGPRGS CCCCCCCCCCCCCCC	28.36	-
289	Dimethylation	FPRVAGPRGSGPPMR CCCCCCCCCCCCCCC	51.49	-
289	Methylation	FPRVAGPRGSGPPMR CCCCCCCCCCCCCCC	51.49	-
291	Phosphorylation	RVAGPRGSGPPMRLV CCCCCCCCCCCCCCE	49.78	23140645
296	Methylation	RGSGPPMRLVEPVGR CCCCCCCCCEECCCC	41.16	-
342	Phosphorylation	YTEKLKFSDEEDGRD CHHHCCCCCCCCCCC	42.39	25521595
350	Phosphorylation	DEEDGRDSDEEGAEG CCCCCCCCCHHHHCC	45.63	25521595
361	Phosphorylation	GAEGHKDSQSAAAEE HHCCCCCCCCCHHCC	30.73	23684622
363	Phosphorylation	EGHKDSQSAAAEEPE CCCCCCCCCHHCCCC	24.67	25521595
377	Phosphorylation	ETDGKKGTSPGSELP CCCCCCCCCCCCCCC	40.40	22942356
378	Phosphorylation	TDGKKGTSPGSELPP CCCCCCCCCCCCCCC	35.61	25521595
381	Phosphorylation	KKGTSPGSELPPPKT CCCCCCCCCCCCCCC	39.07	27087446
405	Phosphorylation	ETEPAPPTPKPPPPP CCCCCCCCCCCCCCC	42.77	23684622
454	Phosphorylation	WRQRRKQSSSEISLA HHHHHHHCHHHHHHH	38.58	25521595
455	Phosphorylation	RQRRKQSSSEISLAV HHHHHHCHHHHHHHH	29.51	27742792
456	Phosphorylation	QRRKQSSSEISLAVE HHHHHCHHHHHHHHH	44.17	26824392
459	Phosphorylation	KQSSSEISLAVERAR HHCHHHHHHHHHHHH	13.26	25619855
535	Phosphorylation	AAPALPPTPTPTPEK CCCCCCCCCCCCCCC	37.54	27180971
537	Phosphorylation	PALPPTPTPTPEKEP CCCCCCCCCCCCCCC	42.12	26643407
539	Phosphorylation	LPPTPTPTPEKEPEE CCCCCCCCCCCCCCC	46.70	26643407
608	Phosphorylation	PEEVPPPTTPPAPKM CCCCCCCCCCCCCCC	58.68	25521595
609	Phosphorylation	EEVPPPTTPPAPKME CCCCCCCCCCCCCCC	32.80	27087446
630	Phosphorylation	GSTRQPPSQGLGYPK CCCCCCCCCCCCCCH	43.49	22802335
635	Phosphorylation	PPSQGLGYPKYQKSL CCCCCCCCCHHHHCC	11.12	22802335
641	Phosphorylation	GYPKYQKSLPPRFQR CCCHHHHCCCHHHHH	30.50	18779572
671	Phosphorylation	WQQQQQGTAPPAPVP HHHHHCCCCCCCCCC	31.49	23140645
680	Phosphorylation	PPAPVPPSPPQPVTL CCCCCCCCCCCCCEE	43.04	23140645
686	Phosphorylation	PSPPQPVTLGAVPAP CCCCCCCEECCCCCC	26.59	23140645
722	Methylation	PPMNFDPRWMMIPPY CCCCCCCCCCCCCCC	35.45	-
738	Methylation	DPRLLQGRPPLDFYP CHHHHCCCCCCCCCC	19.39	-
759	Phosphorylation	GLVPRERSDSGGSSS CCCCCCCCCCCCCCC	31.23	27087446
761	Phosphorylation	VPRERSDSGGSSSEP CCCCCCCCCCCCCCC	46.42	27087446
764	Phosphorylation	ERSDSGGSSSEPFER CCCCCCCCCCCCHHH	33.93	27087446
765	Phosphorylation	RSDSGGSSSEPFERH CCCCCCCCCCCHHHH	41.83	25521595
766	Phosphorylation	SDSGGSSSEPFERHA CCCCCCCCCCHHHHC	51.49	27087446
782	Phosphorylation	PLLRERGTPPVDPKL CHHHHCCCCCCCCCC	30.55	25521595
797	Phosphorylation	AWVGDVFTTTPTDPR EECCCEEECCCCCCC	29.61	25619855
798	Phosphorylation	WVGDVFTTTPTDPRP ECCCEEECCCCCCCC	21.22	25619855
799	Phosphorylation	VGDVFTTTPTDPRPL CCCEEECCCCCCCCC	22.57	21082442
801	Phosphorylation	DVFTTTPTDPRPLTS CEEECCCCCCCCCCC	57.45	25619855
807	Phosphorylation	PTDPRPLTSPLRQAA CCCCCCCCCHHHHHC	30.86	26824392
808	Phosphorylation	TDPRPLTSPLRQAAD CCCCCCCCHHHHHCH	29.62	27087446
820	Phosphorylation	AADEEEKSMRSETPP HCHHHHHHHHCCCCC	23.78	26643407
823	Phosphorylation	EEEKSMRSETPPVPP HHHHHHHCCCCCCCC	36.86	27087446
825	Phosphorylation	EKSMRSETPPVPPPP HHHHHCCCCCCCCCC	33.85	22942356
834	Phosphorylation	PVPPPPPYLANYPGF CCCCCCCCHHCCCCC	24.99	21659605
838	Phosphorylation	PPPYLANYPGFPENG CCCCHHCCCCCCCCC	10.10	23984901
846	Phosphorylation	PGFPENGTPGPPISR CCCCCCCCCCCCCCC	36.33	23984901
852	Phosphorylation	GTPGPPISRFPLEES CCCCCCCCCCCCCCC	33.37	25777480
889	Phosphorylation	PPPKKEPSKEEPPQL CCCCCCCCCCCCCCC	54.51	26824392
897	Phosphorylation	KEEPPQLSGPEAGRK CCCCCCCCCCCCCCC	47.24	25777480
907	Methylation	EAGRKPARGGQGPPP CCCCCCCCCCCCCCC	59.30	24129315
931	Phosphorylation	RWGPRPGSCRRGIPP CCCCCCCCCCCCCCC	13.72	24719451
967	Phosphorylation	VEELPPKSLEQGDET CCCCCCCHHCCCCCC	42.80	27841257
974	Phosphorylation	SLEQGDETPKVPKPD HHCCCCCCCCCCCCC	32.90	25521595
995	Phosphorylation	GKVGPKETPPGGNLS CCCCCCCCCCCCCCC	40.69	21082442
1002	Phosphorylation	TPPGGNLSPAPRLRR CCCCCCCCCCCCCCC	24.02	27087446
1011	Phosphorylation	APRLRRDYSYERVGP CCCCCCCCCCCCCCC	16.02	26643407
1012	Phosphorylation	PRLRRDYSYERVGPT CCCCCCCCCCCCCCC	25.47	27087446
1013	Phosphorylation	RLRRDYSYERVGPTS CCCCCCCCCCCCCCC	11.09	26643407
1064	Methylation	EFRGDDGRGGGSGGT ECCCCCCCCCCCCCC	47.80	24129315
1068	Phosphorylation	DDGRGGGSGGTNHPS CCCCCCCCCCCCCCC	37.01	24899341
1071	Phosphorylation	RGGGSGGTNHPSAPR CCCCCCCCCCCCCCC	33.60	28066266
1081	Phosphorylation	PSAPRGRTASETRSE CCCCCCCCCHHHCCC	37.04	25521595
1083	Phosphorylation	APRGRTASETRSEGS CCCCCCCHHHCCCCC	38.60	25521595
1085	Phosphorylation	RGRTASETRSEGSEY CCCCCHHHCCCCCCC	36.68	25521595
1087	Phosphorylation	RTASETRSEGSEYEE CCCHHHCCCCCCCCC	54.45	27087446
1090	Phosphorylation	SETRSEGSEYEEIPK HHHCCCCCCCCCCCH	32.71	25521595
1092	Phosphorylation	TRSEGSEYEEIPKRR HCCCCCCCCCCCHHH	22.13	25521595
1104	Phosphorylation	KRRRQRGSETGSETH HHHHHCCCCCCCCCC	33.89	27087446
1106	Phosphorylation	RRQRGSETGSETHES HHHCCCCCCCCCCHH	47.94	27087446
1108	Phosphorylation	QRGSETGSETHESDL HCCCCCCCCCCHHHC	46.90	27087446
1110	Phosphorylation	GSETGSETHESDLAP CCCCCCCCCHHHCCC	32.42	27087446
1113	Phosphorylation	TGSETHESDLAPSDK CCCCCCHHHCCCCCC	30.25	27087446
1118	Phosphorylation	HESDLAPSDKEAPPP CHHHCCCCCCCCCCC	56.56	26824392
1145	Phosphorylation	PQPGAPPSPAPARFS CCCCCCCCCCCCCCC	32.41	27087446
1167	Phosphorylation	FTPRGVPSRRGRGGG ECCCCCCCCCCCCCC	32.00	18779572
1194	Acetylation	AKSLVPKKPPTGPLP HHHCCCCCCCCCCCC	50.59	-
1197	Phosphorylation	LVPKKPPTGPLPPSK CCCCCCCCCCCCCCC	61.02	25159016
1203	Phosphorylation	PTGPLPPSKEPLKEK CCCCCCCCCCCHHHH	47.95	27357545
1213	Phosphorylation	PLKEKLISGPLSPMS CHHHHHHCCCCCCCC	44.81	25619855
1217	Phosphorylation	KLISGPLSPMSRAGN HHHCCCCCCCCCCCC	22.99	24925903
1219	Oxidation	ISGPLSPMSRAGNMG HCCCCCCCCCCCCCC	3.68	17242355
1220	Phosphorylation	SGPLSPMSRAGNMGV CCCCCCCCCCCCCCC	23.51	24925903
1298	Phosphorylation	VPPPPRRTAAKSPDL CCCCCCCCCCCCCCC	32.04	25159016
1302	Phosphorylation	PRRTAAKSPDLSNQN CCCCCCCCCCCCCCC	20.94	27087446
1306	Phosphorylation	AAKSPDLSNQNSDQA CCCCCCCCCCCHHHH	43.69	25159016
1310	Phosphorylation	PDLSNQNSDQANEEW CCCCCCCHHHHHHHH	22.72	25159016
1319	Phosphorylation	QANEEWETASESSDF HHHHHHHHHHHHHCH	36.23	25159016
1321	Phosphorylation	NEEWETASESSDFAS HHHHHHHHHHHCHHH	45.49	25159016
1323	Phosphorylation	EWETASESSDFASER HHHHHHHHHCHHHHH	32.48	25159016
1324	Phosphorylation	WETASESSDFASERR HHHHHHHHCHHHHHC	32.47	25159016
1328	Phosphorylation	SESSDFASERRGDKE HHHHCHHHHHCCCCC	31.46	23608596
1336	Phosphorylation	ERRGDKETPPAALMT HHCCCCCCCCHHHHC	40.07	24899341
1343	Phosphorylation	TPPAALMTSKAVGTP CCCHHHHCCCCCCCC	28.11	-
1349	Phosphorylation	MTSKAVGTPGANAGG HCCCCCCCCCCCCCC	16.38	26745281
1362	Phosphorylation	GGAGPGISAMSRGDL CCCCCCCHHHHHCCH	24.67	29514104
1365	Phosphorylation	GPGISAMSRGDLSQR CCCCHHHHHCCHHHH	32.59	29514104
1380	Phosphorylation	AKDLSKRSFSSQRPG HHHHHHHCHHCCCCC	32.96	29233185
1382	Phosphorylation	DLSKRSFSSQRPGMD HHHHHCHHCCCCCCC	27.14	26824392
1383	Phosphorylation	LSKRSFSSQRPGMDR HHHHCHHCCCCCCCC	28.35	26643407
1400	Acetylation	RRPGTGGKTGSGGGS CCCCCCCCCCCCCCC	51.57	23806337
1401	Phosphorylation	RPGTGGKTGSGGGSS CCCCCCCCCCCCCCC	39.59	-
1403	Phosphorylation	GTGGKTGSGGGSSGG CCCCCCCCCCCCCCC	39.22	23684622
1408	Phosphorylation	TGSGGGSSGGGGAGP CCCCCCCCCCCCCCC	44.74	29899451
1428	Phosphorylation	PGRGDKRSWPSPKNR CCCCCCCCCCCCCCC	49.43	25338131
1431	Phosphorylation	GDKRSWPSPKNRSRP CCCCCCCCCCCCCCC	42.10	22324799
1467	Phosphorylation	RLDQVIHSNPAGIQQ EHHHHHHCCHHHHHH	33.13	25367039
1480	Phosphorylation	QQALAQLSSRQGNVT HHHHHHHHHCCCCCC	16.05	25367039
1481	Phosphorylation	QALAQLSSRQGNVTA HHHHHHHHCCCCCCC	36.90	25367039
1487	Phosphorylation	SSRQGNVTAPGGHPR HHCCCCCCCCCCCCC	31.00	25367039
1506	Phosphorylation	PPQAPQGSSPRPPTR CCCCCCCCCCCCCCC	31.74	26643407
1507	Phosphorylation	PQAPQGSSPRPPTRY CCCCCCCCCCCCCCC	31.58	26643407
1512	Phosphorylation	GSSPRPPTRYDPPRA CCCCCCCCCCCCCCH	44.54	26643407
1514	Phosphorylation	SPRPPTRYDPPRASS CCCCCCCCCCCCHHH	34.97	25367039
1521	Phosphorylation	YDPPRASSAISSDPH CCCCCHHHHHCCCCC	28.74	-
1524	Phosphorylation	PRASSAISSDPHFEE CCHHHHHCCCCCCCC	28.53	28059163
1603	Phosphorylation	DSGTEALTPHIWNRL CCCCHHCCHHHHHHC	21.62	29514104
1667	Phosphorylation	GPCSQRSSPDGGLKG CCCCCCCCCCCCCCC	29.24	25521595
1675	Phosphorylation	PDGGLKGSAEGPPKR CCCCCCCCCCCCCCC	22.89	25619855
1681	Acetylation	GSAEGPPKRPGGPSP CCCCCCCCCCCCCCC	74.49	2373503
1687	Phosphorylation	PKRPGGPSPLNAVPG CCCCCCCCCCCCCCC	45.34	26824392
1696	Phosphorylation	LNAVPGESASGSEPS CCCCCCCCCCCCCCC	33.38	23984901
1698	Phosphorylation	AVPGESASGSEPSEP CCCCCCCCCCCCCCC	52.73	25619855
1757	Phosphorylation	RPAHRPGSQVEFGTT CCCCCCCCCCEEECC	33.46	28066266
1763	Phosphorylation	GSQVEFGTTNKDSDL CCCCEEECCCCCCCE	32.30	24719451
1764	Phosphorylation	SQVEFGTTNKDSDLC CCCEEECCCCCCCEE	40.42	24719451
1787	Phosphorylation	GEKELVASATEAVPI CCHHHHHECCEEECC	28.39	29514104
1807	Phosphorylation	LLPSASTSAEPQPKS HCCCCCCCCCCCCCC	28.30	25338131
2037	Phosphorylation	PAARVLPSPARPFAP CHHHCCCCCCCCCCC	27.34	-
2077	Phosphorylation	GGPGSSRTPPSGRPF CCCCCCCCCCCCCCC	41.31	-
2098	Phosphorylation	LKAPPSTYSGVFRTQ CCCCCCCCCCCEEHH	14.04	22817900
2110	Phosphorylation	RTQRIDLYQQASPPD EHHEEEHHHHCCCCC	8.54	22817900
2114	Phosphorylation	IDLYQQASPPDALRW EEHHHHCCCCCHHHC	32.40	25266776

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
609	T	Phosphorylation	Kinase	MAPK1	P63085	GPS
1002	S	Phosphorylation	Kinase	MAPK1	P63085	GPS
1217	S	Phosphorylation	Kinase	MAPK1	P63085	GPS

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of PRC2A_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of PRC2A_MOUSE !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
Oops, there are no PPI records of PRC2A_MOUSE !!

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of PRC2A_MOUSE

Related Literatures of Post-Translational Modification

Phosphorylation
Reference	PubMed
"Large scale localization of protein phosphorylation by use ofelectron capture dissociation mass spectrometry."; Sweet S.M., Bailey C.M., Cunningham D.L., Heath J.K., Cooper H.J.; Mol. Cell. Proteomics 8:904-912(2009). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-808 AND SER-1217, ANDMASS SPECTROMETRY.	19131326 [Abstract]
"The phagosomal proteome in interferon-gamma-activated macrophages."; Trost M., English L., Lemieux S., Courcelles M., Desjardins M.,Thibault P.; Immunity 30:143-154(2009). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-166, AND MASSSPECTROMETRY.	19144319 [Abstract]
"Solid tumor proteome and phosphoproteome analysis by high resolutionmass spectrometry."; Zanivan S., Gnad F., Wickstroem S.A., Geiger T., Macek B., Cox J.,Faessler R., Mann M.; J. Proteome Res. 7:5314-5326(2008). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-342; SER-350; SER-1087AND SER-1090, AND MASS SPECTROMETRY.	19367708 [Abstract]
"Large-scale phosphorylation analysis of mouse liver."; Villen J., Beausoleil S.A., Gerber S.A., Gygi S.P.; Proc. Natl. Acad. Sci. U.S.A. 104:1488-1493(2007). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-759; SER-761; SER-1087;SER-1090 AND SER-1217, AND MASS SPECTROMETRY.	17242355 [Abstract]
"Qualitative and quantitative analyses of protein phosphorylation innaive and stimulated mouse synaptosomal preparations."; Munton R.P., Tweedie-Cullen R., Livingstone-Zatchej M., Weinandy F.,Waidelich M., Longo D., Gehrig P., Potthast F., Rutishauser D.,Gerrits B., Panse C., Schlapbach R., Mansuy I.M.; Mol. Cell. Proteomics 6:283-293(2007). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-609; SER-1002 ANDSER-1217, AND MASS SPECTROMETRY.	17114649 [Abstract]
"Comprehensive identification of phosphorylation sites in postsynapticdensity preparations."; Trinidad J.C., Specht C.G., Thalhammer A., Schoepfer R.,Burlingame A.L.; Mol. Cell. Proteomics 5:914-922(2006). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-782, AND MASSSPECTROMETRY.	16452087 [Abstract]