dbPTM

PPR3E_HUMAN - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	PPR3E_HUMAN
UniProt AC	Q9H7J1
Protein Name	Protein phosphatase 1 regulatory subunit 3E
Gene Name	PPP1R3E
Organism	Homo sapiens (Human).
Sequence Length	279
Subcellular Localization
Protein Description	Acts as a glycogen-targeting subunit for PP1. PP1 is involved in glycogen metabolism and contributes to the activation of glycogen synthase leading to an increase in glycogen synthesis..
Protein Sequence	MSRERPPGTDIPRNLSFIAALTERAYYRSQRPSLEEEPEEEPGEGGTRFGARSRAHAPSRGRRARSAPAGGGGARAPRSRSPDTRKRVRFADALGLELAVVRRFRPGELPRVPRHVQIQLQRDALRHFAPCQPRARGLQEARAALEPASEPGFAARLLTQRICLERAEAGPLGVAGSARVVDLAYEKRVSVRWSADGWRSQREAPAAYAGPAPPPPRADRFAFRLPAPPIGGALLFALRYRVTGHEFWDNNGGRDYALRGPEHPGSGGAPEPQGWIHFI

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
16	Phosphorylation	TDIPRNLSFIAALTE CCCCCCHHHHHHHHH	20.39	22617229
22	Phosphorylation	LSFIAALTERAYYRS HHHHHHHHHHHHHHH	20.78	23403867
29	Phosphorylation	TERAYYRSQRPSLEE HHHHHHHHCCCCCCC	17.89	23401153
33	Phosphorylation	YYRSQRPSLEEEPEE HHHHCCCCCCCCCCC	51.07	23401153
66	Phosphorylation	SRGRRARSAPAGGGG CCCCCCCCCCCCCCC	37.30	25849741
81	Phosphorylation	ARAPRSRSPDTRKRV CCCCCCCCCCHHHHH	28.51	22798277
190	Phosphorylation	LAYEKRVSVRWSADG CEEEECEEEEEECCC	15.25	29396449

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of PPR3E_HUMAN !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of PPR3E_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of PPR3E_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
Oops, there are no PPI records of PPR3E_HUMAN !!

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of PPR3E_HUMAN

Related Literatures of Post-Translational Modification