PPR21_MOUSE - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: PPR21_MOUSE
• UniProt AC: Q3TDD9
• Protein Name: Protein phosphatase 1 regulatory subunit 21
• Gene Name: Ppp1r21
• Organism: Mus musculus (Mouse).
• Sequence Length: 780
• Protein Sequence: MASAELQGKYQKLAQEYSKLRAQNQVLKKGVVDEQASSAALKEQLKMKDQSLRKLQQEMDSLTFRNLQLAKRVELLQDELALSEPRGKKNKKSGESSSQLSQEQKSVFDEDLQKKIEENERLHIQFFEADEHHRHVEAELRSRLATLETEAAQHQAVIDGLTRKYMETIEKLQSDKAKLEVKSQTLEKEAKECRLRTEECQLQLKNLHEDLSGRLEESLSIINEKVPFNDTKCHLYNALNVPLHNRRHQLKMRDIAGQALAFVQDLVPALLNFHTYTEQRIQIFPVDSAIDTISPLNQKFSQYLHENASYVRPLEEGMLHLFESITEDTVTVLETTVKLKMFSDHLTSYVRFLRKILPYQLKSLEEECESSLCTPALRARNLELSQDMKTMTAVFEKLQTYVTLLALPSTEPDGLLRTNYTSVLTNVGAALHGFHDVMKDISKHYSQKASIEHEIPTATQKLVTTNDCILSSAVTLTNGAGKIASFFGNNVDYFIASLSYGPKTASGFISPLSAECMLQYKKKAAAYMKSLRTPLAESVPYGEAVANRRVLLSSTESREGLAQQVQQSLEKISKLEQEKEHWMLEAQLAKIKLEKENQRIADRLRGTTSAQLPGLAQENATVPIASSQEEAAAKVLTEPVQSTSLVGMLTRTPDSEAPDVESREDLIKSHYMARIAELTSQLQLADSKSVHFYAECRALSKRLALAEKSKETLTEEMRLASQNISRLQDELMTTKRSYEDQLSMMSDHLCSMNETLSKQREEIDTLKMASKGNSKKTRNR

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
9	Acetylation	ASAELQGKYQKLAQE CHHHHHHHHHHHHHH	31.39	15626019
17	Phosphorylation	YQKLAQEYSKLRAQN HHHHHHHHHHHHHHH	10.06	-
83	Phosphorylation	LQDELALSEPRGKKN HHHHHHHCCCCCCCC	39.69	-
93	Phosphorylation	RGKKNKKSGESSSQL CCCCCCCCCCCHHHH	49.77	27841257
96	Phosphorylation	KNKKSGESSSQLSQE CCCCCCCCHHHHCHH	38.52	23140645
97	Phosphorylation	NKKSGESSSQLSQEQ CCCCCCCHHHHCHHH	20.15	23140645
98	Phosphorylation	KKSGESSSQLSQEQK CCCCCCHHHHCHHHH	44.41	23140645
101	Phosphorylation	GESSSQLSQEQKSVF CCCHHHHCHHHHHHC	24.84	27841257
471	Phosphorylation	TTNDCILSSAVTLTN ECCCCHHHCCEEECC	9.06	28494245
472	Phosphorylation	TNDCILSSAVTLTNG CCCCHHHCCEEECCC	24.26	28494245
485	Phosphorylation	NGAGKIASFFGNNVD CCCCHHHHHHCCCCC	25.28	28494245
609	Phosphorylation	DRLRGTTSAQLPGLA HHHCCCCHHHCCCHH	17.54	25338131
652	Phosphorylation	LVGMLTRTPDSEAPD HHEECCCCCCCCCCC	26.64	25521595

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of PPR21_MOUSE !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of PPR21_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of PPR21_MOUSE !!

Protein-Protein Interaction

Oops, there are no PPI records of PPR21_MOUSE !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.