PPM1G_MOUSE - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: PPM1G_MOUSE
• UniProt AC: Q61074
• Protein Name: Protein phosphatase 1G
• Gene Name: Ppm1g
• Organism: Mus musculus (Mouse).
• Sequence Length: 542
• Subcellular Localization: Nucleus . Membrane ; Lipid-anchor .
• Protein Description: May be involved in regulation of cell cycle..
• Protein Sequence: MGAYLSQPNTVKCSGDGVGAPRLPLPYGFSAMQGWRVSMEDAHNCIPELDNETAMFSVYDGHGGEEVALYCAKYLPDIIKDQKAYKEGKLQKALQDAFLAIDAKLTTEEVIKELAQIAGRPTEDEDDKDKVADEDDVDNEEAALLHEEATMTIEELLTRYGQNCQKVPPHTKSGIGTGDEPGPQGLNGEAGPEDPSRETPSQENGPTAKGHTGFSSNSEHGTEAGQISEPGTATGEAGPSCSSASDKLPRVAKSKFFEDSEDESDEVEEEEDDSEECSEDEDGYSSEEAENEEDEDDTEEAEEDDDEEMMVPGMEGKEEPGSDSGTTAVVALIRGKQLIVANAGDSRCVVSEAGKALDMSYDHKPEDEVELARIKNAGGKVTMDGRVNGGLNLSRAIGDHFYKRNKNLPPQEQMISALPDIKVLTLTDDHEFMVIACDGIWNVMSSQEVVDFIQSKISQRDENGELRLLSSIVEELLDQCLAPDTSGDGTGCDNMTCIIICFKPRNTVELQAESGKRKLEEALSTEGAEDTGNSDKKKAKRD

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
2	Myristoylation	------MGAYLSQPN ------CCCCCCCCC	23.95	-
4	Phosphorylation	----MGAYLSQPNTV ----CCCCCCCCCCE	10.93	18779572
10	Phosphorylation	AYLSQPNTVKCSGDG CCCCCCCCEECCCCC	28.20	18779572
13	S-nitrosocysteine	SQPNTVKCSGDGVGA CCCCCEECCCCCCCC	4.83	-
13	S-nitrosylation	SQPNTVKCSGDGVGA CCCCCEECCCCCCCC	4.83	19101475
22	Methylation	GDGVGAPRLPLPYGF CCCCCCCCCCCCCCC	48.69	-
112	Acetylation	LTTEEVIKELAQIAG CCHHHHHHHHHHHHC	52.42	19859139
122	Phosphorylation	AQIAGRPTEDEDDKD HHHHCCCCCCCCCCC	55.50	-
128	Acetylation	PTEDEDDKDKVADED CCCCCCCCCCCCCHH	72.30	19859147
164	Glutathionylation	LTRYGQNCQKVPPHT HHHHCCCCCCCCCCC	2.97	24333276
166	Ubiquitination	RYGQNCQKVPPHTKS HHCCCCCCCCCCCCC	59.93	-
196	Phosphorylation	EAGPEDPSRETPSQE CCCCCCCCCCCCCCC	55.88	28285833
199	Phosphorylation	PEDPSRETPSQENGP CCCCCCCCCCCCCCC	27.42	25293948
201	Phosphorylation	DPSRETPSQENGPTA CCCCCCCCCCCCCCC	58.51	19060867
207	Phosphorylation	PSQENGPTAKGHTGF CCCCCCCCCCCCCCC	42.26	25293948
247	Ubiquitination	SCSSASDKLPRVAKS CCCCCHHCCCHHHHH	58.87	22790023
322	Phosphorylation	EGKEEPGSDSGTTAV CCCCCCCCCCCCHHH	39.04	26525534
324	Phosphorylation	KEEPGSDSGTTAVVA CCCCCCCCCCHHHEE	39.47	25293948
326	Phosphorylation	EPGSDSGTTAVVALI CCCCCCCCHHHEEEE	18.61	25293948
336	Ubiquitination	VVALIRGKQLIVANA HEEEECCCEEEEEEC	31.89	22790023
348	Glutathionylation	ANAGDSRCVVSEAGK EECCCCCEEEECCCC	4.03	24333276
380	Acetylation	RIKNAGGKVTMDGRV EEECCCCEEEECCEE	33.35	23806337
380	Ubiquitination	RIKNAGGKVTMDGRV EEECCCCEEEECCEE	33.35	-
516	Acetylation	ELQAESGKRKLEEAL EEHHHHHHHHHHHHH	56.49	68327
516	Ubiquitination	ELQAESGKRKLEEAL EEHHHHHHHHHHHHH	56.49	27667366
524	Phosphorylation	RKLEEALSTEGAEDT HHHHHHHHCCCCCCC	31.31	25521595
525	Phosphorylation	KLEEALSTEGAEDTG HHHHHHHCCCCCCCC	39.01	27742792
531	Phosphorylation	STEGAEDTGNSDKKK HCCCCCCCCCCHHHH	29.75	25619855
534	Phosphorylation	GAEDTGNSDKKKAKR CCCCCCCCHHHHHHC	52.75	25619855

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of PPM1G_MOUSE !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of PPM1G_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of PPM1G_MOUSE !!

Protein-Protein Interaction

Oops, there are no PPI records of PPM1G_MOUSE !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.