dbPTM

PPM1F_MOUSE - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	PPM1F_MOUSE
UniProt AC	Q8CGA0
Protein Name	Protein phosphatase 1F
Gene Name	Ppm1f
Organism	Mus musculus (Mouse).
Sequence Length	452
Subcellular Localization
Protein Description	Dephosphorylates and concomitantly deactivates CaM-kinase II activated upon autophosphorylation, and CaM-kinases IV and I activated upon phosphorylation by CaM-kinase kinase. Promotes apoptosis (By similarity)..
Protein Sequence	MASGAAQNSSQMACDSEIPGFLDAFLQDFPAPLSLESPLPWKVPGTVLSQEEVEAELIELALGFLGSRNAPPSFAVAVTHEAISQLLQTDLSEFKRLPEQEEEEEEEEEEKALVTLLDAKGLARSFFNCLWKVCSQWQKQVPLTAQAPQWQWLVSIHAIRNTRRKMEDRHVSLPAFNHLFGLSDSVHRAYFAVFDGHGGVDAARYASVHVHTNASHQPELRTNPAAALKEAFRLTDEMFLQKAKRERLQSGTTGVCALIAGAALHVAWLGDSQVILVQQGRVVKLMEPHKPERQDEKARIEALGGFVSLMDCWRVNGTLAVSRAIGDVFQKPYVSGEADAASRELTGSEDYLLLACDGFFDVVPHHEVTGLVHGHLLRHKGNGMRIAEELVAVARDRGSHDNITVMVVFLREPLELLEGGVQGTGDAQADVGSQDLSTGLSELEISNTSQRS

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
64	Ubiquitination	LIELALGFLGSRNAP HHHHHHHHHCCCCCC	7.90	27667366
185	Phosphorylation	HLFGLSDSVHRAYFA HHHCCCHHHHHHHEE	19.22	26060331
229	Ubiquitination	TNPAAALKEAFRLTD CCHHHHHHHHHHHCH	42.12	27667366
331	Ubiquitination	AIGDVFQKPYVSGEA HHHHHHCCCCCCCCC	27.18	22790023
452	Phosphorylation	ISNTSQRS------- ECCCCCCC-------	36.62	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of PPM1F_MOUSE !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of PPM1F_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of PPM1F_MOUSE !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
Oops, there are no PPI records of PPM1F_MOUSE !!

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of PPM1F_MOUSE

Related Literatures of Post-Translational Modification