PPIL1_MOUSE - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: PPIL1_MOUSE
• UniProt AC: Q9D0W5
• Protein Name: Peptidyl-prolyl cis-trans isomerase-like 1
• Gene Name: Ppil1
• Organism: Mus musculus (Mouse).
• Sequence Length: 166
• Subcellular Localization: Nucleus .
• Protein Description: Involved in pre-mRNA splicing as component of the spliceosome. PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides..
• Protein Sequence: MAAIPPDTWQPPNVYLETSMGVIVLELYWKHAPKTCKNFAELARRGYYNGTKFHRIIKDFMIQGGDPTGTGRGGASIYGKQFEDELHPDLKFTGAGILAMANAGPDTNGSQFFVTLAPTQWLDGKHTIFGRVCQGIGMVNRVGMVETNSQDRPVDDVKILKAYPSG

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
37	Acetylation	KHAPKTCKNFAELAR HHCCHHHHCHHHHHH	61.40	22826441
58	Acetylation	TKFHRIIKDFMIQGG CCHHHHHHHHEEECC	42.41	22826441
72	Methylation	GDPTGTGRGGASIYG CCCCCCCCCCCEEEC	39.96	30988925
147	Phosphorylation	NRVGMVETNSQDRPV CCEEEEEECCCCCCC	28.85	28066266
149	Phosphorylation	VGMVETNSQDRPVDD EEEEEECCCCCCCCC	40.66	26643407

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of PPIL1_MOUSE !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of PPIL1_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of PPIL1_MOUSE !!

Protein-Protein Interaction

Oops, there are no PPI records of PPIL1_MOUSE !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.