PPCEL_MOUSE - dbPTM
PPCEL_MOUSE - PTM Information in dbPTM
Basic Information of Protein
UniProt ID PPCEL_MOUSE
UniProt AC Q8C167
Protein Name Prolyl endopeptidase-like
Gene Name Prepl
Organism Mus musculus (Mouse).
Sequence Length 725
Subcellular Localization Cytoplasm, cytosol .
Protein Description Probable serine peptidase whose precise substrate specificity remains unclear. Does not cleave peptides after a arginine or lysine residue. May play a role in the regulation of synaptic vesiscle exocytosis..
Protein Sequence MLQTAKFSLRALKHSIPHLGNCMQKQSYRNVAGPYYSRVRLKKYHLTKCLQNKPRIAGLARNIPSRSFSCKDLLPIKPESEKPISENMDAFEKVRTRLETQPQEEYEVVNAEIKHGGFVYYQEGCCLVRSKDEEADSDNYEVLFNLEELKLDQPFIDCIRVAPDEKYVAAKIRTEDSETSTLVVVKLSDQPVMEASFPNVSSFEWVKDEEDEDVLFYTFQRNLRCHDVYRATFGDNKRNERFYTEKDPSYFVFLYLTKDSRFLTLNIMNKTTSEVWLIDGLSPWDPPVLIQKRIHGMLYYVEHRDDELYILTNVGEPTEFKLMRTAADAPAIMNWDLFFTMKRNTKVVDLDMFKDHCVLFLKHSNLLYVNVIGLADDSVRSLKLPPWACGFIMDTNSDPKNCPFQLCSPIRPPKYYTYKFAEGKLFEETGHEDPITKTSRVLRIEAKSKDGKLVPMTVFHKTDSEDLQRKPLLVHVYGAYGMDLKMNFRPEKRVLVDDGWILAYCHVRGGGELGLQWHADGRLTKKLNGLADLVACIKTLHSQGFSQPSLTTLSAFSAGGVLVGALCNSKPELLRAVTLEAPFLDVLNTMLDTTLPLTLEELEEWGNPSSDEKHKNYIKRYCPCQNIKPQHYPSVHITAYENDERVPLKGIVNYTEKLKEAVAEHTKGAGEGYQPPNIILDIQPGGNHVIEDSHKKITTQMKFLYEELGLDSTDAFEALKKYLKF
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure
ASA (%) Reference Orthologous
Protein Cluster
6 (in isoform 2)Ubiquitination-38.58-
35PhosphorylationYRNVAGPYYSRVRLK
HHCCCCCCHHHHHHH
17.1022817900
44 (in isoform 2)Ubiquitination-10.65-
93 (in isoform 2)Ubiquitination-30.4822790023
93UbiquitinationENMDAFEKVRTRLET
CCHHHHHHHHHHHHC
30.4822790023
130PhosphorylationEGCCLVRSKDEEADS
CCEEEEEECCCCCCC
36.6624925903
131 (in isoform 2)Ubiquitination-59.6022790023
131UbiquitinationGCCLVRSKDEEADSD
CEEEEEECCCCCCCC
59.6022790023
137PhosphorylationSKDEEADSDNYEVLF
ECCCCCCCCCEEEEE
34.5024925903
140PhosphorylationEEADSDNYEVLFNLE
CCCCCCCEEEEEEHH
16.6522324799
171UbiquitinationDEKYVAAKIRTEDSE
CCCEEEEEEECCCCC
24.00-
177PhosphorylationAKIRTEDSETSTLVV
EEEECCCCCCEEEEE
36.2222006019
324MethylationPTEFKLMRTAADAPA
CCCEECCCHHCCCCC
31.4816288521
337 (in isoform 2)Ubiquitination-2.62-
350 (in isoform 2)Ubiquitination-3.30-
418PhosphorylationRPPKYYTYKFAEGKL
CCCCEEEEEEECCCE
6.4928576409
424 (in isoform 2)Ubiquitination-41.3222790023
424UbiquitinationTYKFAEGKLFEETGH
EEEEECCCEECCCCC
41.3222790023
437UbiquitinationGHEDPITKTSRVLRI
CCCCCCCCCEEEEEE
45.2622790023
437 (in isoform 2)Ubiquitination-45.2622790023
438PhosphorylationHEDPITKTSRVLRIE
CCCCCCCCEEEEEEE
17.0824759943
439PhosphorylationEDPITKTSRVLRIEA
CCCCCCCEEEEEEEE
23.1924759943
633 (in isoform 2)Ubiquitination-27.96-
720UbiquitinationTDAFEALKKYLKF--
CHHHHHHHHHHCC--
46.5522790023
720 (in isoform 2)Ubiquitination-46.5522790023

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of PPCEL_MOUSE !!

Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of PPCEL_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10)
Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of PPCEL_MOUSE !!

Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions

Oops, there are no PPI records of PPCEL_MOUSE !!

Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of PPCEL_MOUSE

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Related Literatures of Post-Translational Modification

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