PP2C4_SCHPO - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: PP2C4_SCHPO
• UniProt AC: O14156
• Protein Name: Protein phosphatase 2C homolog 4
• Gene Name: ptc4
• Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
• Sequence Length: 383
• Subcellular Localization: Vacuole membrane ; Peripheral membrane protein .
• Protein Description: Has a role in the regulation of vacuole fusion..
• Protein Sequence: MSIRFLKRLRAPLYIQNAYCSKNYFYRSFIQYYSPSNGPYLKISMNKAPQSLGLCTARGDSPTNQDRMAYGYLNNLKDTTNRDSPFFYGLFDGHGGTECSEFLSTNLGKIIENQDLNDTEKILKEVHSVGGYMAGLKPPFSLRTVLQSRDEDLLWRARLYYSFLQADMDYLTNYARPSPDSAVPGAVGTVAIITSKNNLSYWESDSYIIHLAHVGDTRALLCDSRTGRAHRLTFQHHPADVEEARRLRRYNMGFSRDSFGQKRFAWVANTRSFGDGYKLKKLGVVAEPQLTSIHSLRDDWSFLTLLSDGITDVVSDDEVVDIIKLSESPQDAANNIIRYAQNVGAVDDITCLVVRLPGWKKRTINDFTKNLRLEKSAYHPRRS

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
255	Phosphorylation	RRYNMGFSRDSFGQK HHHHCCCCCCCCCCC	29.46	29996109
258	Phosphorylation	NMGFSRDSFGQKRFA HCCCCCCCCCCCEEE	30.11	25720772

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of PP2C4_SCHPO !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of PP2C4_SCHPO !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of PP2C4_SCHPO !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
HOG1_SCHPO	sty1	physical	22139357

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.