dbPTM

POT12_ARATH - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	POT12_ARATH
UniProt AC	O80739
Protein Name	Putative potassium transporter 12
Gene Name	POT12
Organism	Arabidopsis thaliana (Mouse-ear cress).
Sequence Length	827
Subcellular Localization	Cell membrane Multi-pass membrane protein .
Protein Description	Putative potassium transporter..
Protein Sequence	MEEIEEGSSNNSIRRVGTGSSDRRWVDGSEVDSETPLFSEIRDRDYSFGNLRRRLMKKPKRADSLDVEAMEIAGSHGHNLKDLSLLTTLGIAFQTLGVVYGDMGTSPLYVFSDVFSKVPIRSEVDVLGALSLVIYTIAVIPLAKYVFVVLKANDNGEGGTFALYSLICRYAKVNKLPNQQPADEQISSFRLKLPTPELERALGIKEALETKGYLKTLLLLLVLMGTSMIIGDGILTPAMSVMSAMSGLQGEVKGFGTNALVMSSIVILVALFSIQRFGTGKVGFLFAPVLALWFFSLGAIGIYNLLKYDFTVIRALNPFYIVLFFNKNSKQAWSALGGCVLCITGAEAMFADLGHFSVRSIQMAFTCVVFPCLLLAYMGQAAYLTKHPEASARIFYDSVPKSLFWPVFVIATLAAMIASQAMISATFSCVKQAMALGCFPRLKIIHTSKKRIGQIYIPVINWFLMIMCILVVSIFRSTTHIANAYGIAEVGVMMVSTVLVTLVMLLIWQTNIFLALCFPLIFGSVETIYLLAVLTKILEGGWVPLVFATFFLTVMYIWNYGSVLKYQSEVRERISMDFMRELGSTLGTIRIPGIGLLYNELVQGIPSIFGQFLLTLPAIHSTIIFVCIKYVPVPVVPQEERFLFRRVCPKDYHMFRCIARYGYKDVRKEDSRVFEQLLIESLEKFLRCEALEDALESTLNDFDPDRVSVASDTYTDDLMAPLIHRAKRSEPEQELDSEVLPSSSVGSSMEEDPALEYELAALREATDSGLTYLLAHGDVRAKKNSIFVKKLVINYFYAFLRRNCRAGAANLTVPHMNILQAGMTYMV

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
29	Phosphorylation	DRRWVDGSEVDSETP CCCCCCCCCCCCCCC	29.95	30407730
33	Phosphorylation	VDGSEVDSETPLFSE CCCCCCCCCCCCCHH	48.85	30291188
35	Phosphorylation	GSEVDSETPLFSEIR CCCCCCCCCCCHHHH	29.28	30407730
39	Phosphorylation	DSETPLFSEIRDRDY CCCCCCCHHHHCCCC	39.53	30407730
46	Phosphorylation	SEIRDRDYSFGNLRR HHHHCCCCCHHHHHH	13.54	25561503
47	Phosphorylation	EIRDRDYSFGNLRRR HHHCCCCCHHHHHHH	30.85	30291188
187	Phosphorylation	QPADEQISSFRLKLP CCCCHHHHHHEECCC	24.10	19880383
188	Phosphorylation	PADEQISSFRLKLPT CCCHHHHHHEECCCC	18.93	19880383
575	Phosphorylation	SEVRERISMDFMREL HHHHHHHCHHHHHHH	20.65	19880383
768	Phosphorylation	ALREATDSGLTYLLA HHHHHHHCCCHHHHH	31.20	22074104
772	Phosphorylation	ATDSGLTYLLAHGDV HHHCCCHHHHHCCCC	12.54	22074104

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of POT12_ARATH !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of POT12_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of POT12_ARATH !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
Oops, there are no PPI records of POT12_ARATH !!

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of POT12_ARATH

Related Literatures of Post-Translational Modification

Phosphorylation
Reference	PubMed
"Large-scale Arabidopsis phosphoproteome profiling reveals novelchloroplast kinase substrates and phosphorylation networks."; Reiland S., Messerli G., Baerenfaller K., Gerrits B., Endler A.,Grossmann J., Gruissem W., Baginsky S.; Plant Physiol. 150:889-903(2009). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-47, AND MASSSPECTROMETRY.	19376835 [Abstract]