dbPTM

PORCN_CAEEL - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	PORCN_CAEEL
UniProt AC	Q22329
Protein Name	Protein-serine O-palmitoleoyltransferase porcupine {ECO:0000250\|UniProtKB:Q9JJJ7}
Gene Name	mom-1 {ECO:0000312\|WormBase:T07H6.2}
Organism	Caenorhabditis elegans.
Sequence Length	442
Subcellular Localization	Membrane Multi-pass membrane protein .
Protein Description	Key regulator of the Wnt signaling pathway that mediates lipid modification of Wnt proteins. [PubMed: 10444600]
Protein Sequence	MDNGHGYEEFELLEDGSLGECSTQVANATFLTISKLICLVVAFKFIKHIPISTTVRVYVHVFASTFTVMWFSRNHLQSAIIYNMFSLISLALAIKQFSGYIILAGNISLLIALQNFCRHYRSEDYFLSIRGILMIHIMRLTTVAFNLEKANSNKFRFVQFSSYVEYIYFPPFIIFGPYLSFEQFFKMRDKKWTGSENELGFIIQSLLAIFNAITLAIISSCHFEFFEPSSQFMEDALTAMSFRFSHYFVCLSTQAFVLMLGSDVVVANPLNIEFSRSTLQTVSEWNKPFHTFLHENIFKRRLFNSTACNVFFTFAVSSLLHGLDFQMTITLLALGFIAYSETVFRKRLSARYSMCVAAKACPVRSNSLSCKHRHSNKTGRALIINLFFLMLSMYHLVFTGMTFTDDYSAIGYPFDHAWKIWGSHYYSSFMISFLFLALSKII

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference	Orthologous Protein Cluster
Oops, there are no PTM records of PORCN_CAEEL !!

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of PORCN_CAEEL !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of PORCN_CAEEL !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of PORCN_CAEEL !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
YWZ3_CAEEL	C02B8.3	physical	14704431

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of PORCN_CAEEL

Related Literatures of Post-Translational Modification