PNM8B_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: PNM8B_HUMAN
• UniProt AC: Q9ULN7
• Protein Name: Paraneoplastic antigen-like protein 8B
• Gene Name: PNMA8B {ECO:0000312|HGNC:HGNC:29206}
• Organism: Homo sapiens (Human).
• Sequence Length: 635
• Protein Sequence: MAMSLLQDWCRSLDVDAHRALLVTGIPEGLEQADVEAVLQPTLLPLGTFRLRHMKALMNEKAQAALVEFVEDVNHAAIPREIPGKDGVWRVLWKDRAQDTRVLRQMRRLLLDDGPTQAAEAGTPGEAPTPPASETQAQDSGEVTGQAGSLLGAARNPRRGRRGRRNRTRRNRLTQKGKKRSRGGRPSAPARSEAEDSSDESLGIVIEEIDQGDLSGEEDQSALYATLQAAARELVRQWAPCNSEGEEDGPREFLALVTVTDKSKKEEAEKEPAGAESIRLNTKEDKNGVPDLVALLAVRDTPDEEPVDSDTSESDSQESGDQETEELDNPEFVAIVAYTDPSDPWAREEMLKIASVIESLGWSDEKDKRDPLRQVLSVMSKDTNGTRVKVEEAGREVDAVVLRKAGDDGDLRECISTLAQPDLPPQAKKAGRGLFGGWSEHREDEGGLLELVALLAAQDMAEVMKEEKENAWEGGKYKYPKGKLGEVLALLAARENMGSNEGSEEASDEQSEEESEDTESEASEPEDRASRKPRAKRARTAPRGLTPAGAPPTASGARKTRAGGRGRGRGVTPEKKAGSRGSAQDDAAGSRKKKGSAGAGAHARAGEAKGQAPTGSKAARGKKARRGRRLPPKCR

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
277	Phosphorylation	KEPAGAESIRLNTKE CCCCCCCCEECCCCC		-
277 (in isoform 5)	Phosphorylation	-		-
416	Phosphorylation	GDLRECISTLAQPDL CCHHHHHHHHHCCCC		-
416 (in isoform 5)	Phosphorylation	-		-
417	Phosphorylation	DLRECISTLAQPDLP CHHHHHHHHHCCCCC		-
417 (in isoform 5)	Phosphorylation	-		-
546	Phosphorylation	RTAPRGLTPAGAPPT HCCCCCCCCCCCCCC		27251275
546 (in isoform 5)	Phosphorylation	-		27251275
590	Phosphorylation	AQDDAAGSRKKKGSA CCCCCCCCCCCCCCC		-
590 (in isoform 5)	Phosphorylation	-		-
593	Acetylation	DAAGSRKKKGSAGAG CCCCCCCCCCCCCCC		-
594	Acetylation	AAGSRKKKGSAGAGA CCCCCCCCCCCCCCH		-
609	Acetylation	HARAGEAKGQAPTGS HHCCCCCCCCCCCCC		-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of PNM8B_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of PNM8B_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of PNM8B_HUMAN !!

Protein-Protein Interaction

Oops, there are no PPI records of PNM8B_HUMAN !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.