dbPTM

PMVK_MOUSE - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	PMVK_MOUSE
UniProt AC	Q9D1G2
Protein Name	Phosphomevalonate kinase
Gene Name	Pmvk
Organism	Mus musculus (Mouse).
Sequence Length	192
Subcellular Localization	Cytoplasm, cytosol .
Protein Description
Protein Sequence	MAPLGASPRLVLLFSGKRKSGKDFVTERLKSRLGGNICALLRLSGPLKEEYAREHGLDFQRLLDASTYKETYRRDMICWGEQKRQADPGFFCRKIVEGVSQPIWLVSDTRRTSDIQWFQEAYGAVIQTVRVVASEQSRQQRGWVFTPGVDDAESECGLDNFGNFDWVIENHGDEQCLEDQLEHLLGFIQAKL

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
7	Phosphorylation	-MAPLGASPRLVLLF -CCCCCCCCCEEEEE	14.57	28066266
48	Acetylation	LRLSGPLKEEYAREH HHHCCCCHHHHHHHC	52.19	23236377
48	Malonylation	LRLSGPLKEEYAREH HHHCCCCHHHHHHHC	52.19	26320211
48	Ubiquitination	LRLSGPLKEEYAREH HHHCCCCHHHHHHHC	52.19	-
66	Phosphorylation	FQRLLDASTYKETYR HHHHHCHHCHHHHHC	31.75	28066266
67	Phosphorylation	QRLLDASTYKETYRR HHHHCHHCHHHHHCC	40.09	28066266
68	Phosphorylation	RLLDASTYKETYRRD HHHCHHCHHHHHCCC	12.34	29514104
69	Acetylation	LLDASTYKETYRRDM HHCHHCHHHHHCCCC	43.60	23806337
69	Malonylation	LLDASTYKETYRRDM HHCHHCHHHHHCCCC	43.60	26320211
69	Ubiquitination	LLDASTYKETYRRDM HHCHHCHHHHHCCCC	43.60	-
71	Phosphorylation	DASTYKETYRRDMIC CHHCHHHHHCCCCEE	20.41	26824392
94	Acetylation	DPGFFCRKIVEGVSQ CCCCHHHHHHCCCCC	52.89	22826441

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of PMVK_MOUSE !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of PMVK_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of PMVK_MOUSE !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
Oops, there are no PPI records of PMVK_MOUSE !!

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of PMVK_MOUSE

Related Literatures of Post-Translational Modification