dbPTM

PMT2_SCHPO - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	PMT2_SCHPO
UniProt AC	Q9C100
Protein Name	Dolichyl-phosphate-mannose--protein mannosyltransferase 2
Gene Name	ogm2
Organism	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
Sequence Length	739
Subcellular Localization	Endoplasmic reticulum membrane Multi-pass membrane protein . Nucleus membrane Multi-pass membrane protein .
Protein Description	Transfers mannose from Dol-P-mannose to Ser or Thr residues on proteins..
Protein Sequence	MSYEQLHAQSGQLRQRFPSKHSEIEDEVANEKEELKDATKSALGEVKTNKKYYILGYFLVPLLLTVIAGFVRVWKIADSNVVIWDEAHFGKFASYYLKHEFYFDVHPPLGKMLNAVAGKLVGYDGSFDFSSGATYPEDLNYKFMRLWNAAFGTLCIPLVYFTALNFNYSFLAATLCTLMVALDNHLATISRFILLDSMLLFFIISTFFCLSRYHVYHKAPFTFYWFKWLFLTGVCIGCVCSVKLVGLFITAVVGLYTVDELWCLLNDKRVTWKAYAGHWIARVCLLIFLPILIYAFTFWIQFAVLYRSGPGDAQMPSLFQARLEGSPLTKNPIDLMYGSKFTLKSRNPTGALLHSHVQTYPEGSEQQQVTGYHHKDGNNEWMFVPTHGVAYNYEENDPMNPILNGSVVRLIHPFTNRNLHTHKIPAPLNKRMYEVSGYGLGDVGDEKDYWIVNILYDTAHRDAYNVRSLSTVFQLYNPVVGCYLSSSSSSLPSWGFGQIEMYCDPDPDPSNTDTQWNVEEHINPRLPEGSINDYPSSFWSDFLHLNRAMLRANNGLIPDEDKLDALRSEAYQWPFLLATLRMCGWGDNQIKYLLVGNPVAYWFATSSLIVFALFVVGAVLAWRRRVLRWSQEACDTFHYAGIYPFLGWFFNYLPYYIMGRVLYVHHYEPSYALSTFTAAFVVDWFTKKMPKIVRVVVFISLYAIIAGVFIYFKDVTFGMHGPASDFHRLRWLNSWNVHD

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
2	Phosphorylation	------MSYEQLHAQ ------CCHHHHHHH	37.06	24763107
22	Phosphorylation	QRFPSKHSEIEDEVA HHCCCCCHHHHHHHH	43.96	24763107
167	N-linked_Glycosylation	YFTALNFNYSFLAAT HHHHHCCCHHHHHHH	30.39	-
404	N-linked_Glycosylation	DPMNPILNGSVVRLI CCCCCCCCCCEEEEE	41.22	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of PMT2_SCHPO !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of PMT2_SCHPO !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of PMT2_SCHPO !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
Oops, there are no PPI records of PMT2_SCHPO !!

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of PMT2_SCHPO

Related Literatures of Post-Translational Modification