PME5_ARATH - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: PME5_ARATH
• UniProt AC: Q5MFV8
• Protein Name: Pectinesterase 5
• Gene Name: PME5
• Organism: Arabidopsis thaliana (Mouse-ear cress).
• Sequence Length: 595
• Subcellular Localization: Cell membrane . Secreted, cell wall . Golgi apparatus membrane . Distributed in the whole pollen tube, including the plasma membrane and pollen tube wall (PubMed:15659637). Cleaved in the Golgi apparatus by SBT6.1 (S1P) after the Arg-Arg-Leu-Leu (RRL
• Protein Description: Acts in the modification of cell walls via demethylesterification of cell wall pectin. Plays an important role in growth of pollen tubes in female floral tissues, possibly via enhancing the interaction between the pollen tube and female floral tissues by modification of the cell walls. [PubMed: 15659637 May be regulated by MYB80 during anther development and play a role in tapetum and pollen development]
• Protein Sequence: MIGKVVVSVASILLIVGVAIGVVAYINKNGDANLSPQMKAVRGICEATSDKASCVKTLEPVKSDDPNKLIKAFMLATRDAITQSSNFTGKTEGNLGSGISPNNKAVLDYCKKVFMYALEDLSTIVEEMGEDLNQIGSKIDQLKQWLTGVYNYQTDCLDDIEEDDLRKTIGEGIASSKILTSNAIDIFHTVVSAMAKLNLKVEDFKNMTGGIFAPSDKGAAPVNKGTPPVADDSPVADPDGPARRLLEDIDETGIPTWVSGADRKLMTKAGRGSNDGGARIRATFVVAKDGSGQFKTVQQAVNACPEKNPGRCIIHIKAGIYREQVIIPKKKNNIFMFGDGARKTVISYNRSVKLSPGTTTSLSGTVQVESEGFMAKWIGFKNTAGPMGHQAVAIRVNGDRAVIFNCRFDGYQDTLYVNNGRQFYRNIVVSGTVDFIFGKSATVIQNSLIVVRKGNKGQFNTVTADGNEKGLAMKIGIVLQNCRIVPDKKLAAERLIVESYLGRPWKKFSTTVIINSEIGDVIRPEGWKIWDGESFHKSCRYVEYNNRGPGAITNRRVNWVKIARSAAEVNDFTVANWLGPINWIQEANVPVTLGL

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
86	N-linked_Glycosylation	DAITQSSNFTGKTEG HHHHHCCCCCCCCCC	43.69	-
206	N-linked_Glycosylation	LKVEDFKNMTGGIFA CCHHHHCCCCCCEEC	32.99	-
349	N-linked_Glycosylation	RKTVISYNRSVKLSP CCEEEEECCCEEECC	23.98	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of PME5_ARATH !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of PME5_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of PME5_ARATH !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.