dbPTM

PME3_ARATH - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	PME3_ARATH
UniProt AC	O49006
Protein Name	Pectinesterase/pectinesterase inhibitor 3
Gene Name	PME3
Organism	Arabidopsis thaliana (Mouse-ear cress).
Sequence Length	592
Subcellular Localization	Secreted, extracellular space, apoplast . Secreted, cell wall.
Protein Description	Acts in the modification of cell walls via demethylesterification of cell wall pectin..
Protein Sequence	MAPSMKEIFSKDNFKKNKKLVLLSAAVALLFVAAVAGISAGASKANEKRTLSPSSHAVLRSSCSSTRYPELCISAVVTAGGVELTSQKDVIEASVNLTITAVEHNYFTVKKLIKKRKGLTPREKTALHDCLETIDETLDELHETVEDLHLYPTKKTLREHAGDLKTLISSAITNQETCLDGFSHDDADKQVRKALLKGQIHVEHMCSNALAMIKNMTDTDIANFEQKAKITSNNRKLKEENQETTVAVDIAGAGELDSEGWPTWLSAGDRRLLQGSGVKADATVAADGSGTFKTVAAAVAAAPENSNKRYVIHIKAGVYRENVEVAKKKKNIMFMGDGRTRTIITGSRNVVDGSTTFHSATVAAVGERFLARDITFQNTAGPSKHQAVALRVGSDFSAFYNCDMLAYQDTLYVHSNRQFFVKCLIAGTVDFIFGNAAVVLQDCDIHARRPNSGQKNMVTAQGRTDPNQNTGIVIQKCRIGATSDLQSVKGSFPTYLGRPWKEYSQTVIMQSAISDVIRPEGWSEWTGTFALNTLTYREYSNTGAGAGTANRVKWRGFKVITAAAEAQKYTAGQFIGGGGWLSSTGFPFSLGL

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
96	N-linked_Glycosylation	DVIEASVNLTITAVE CEEEEEEEEEEEEEE	29.04	-
215	N-linked_Glycosylation	NALAMIKNMTDTDIA HHHHHHHCCCCCCCC	27.88	-
379	Phosphorylation	RDITFQNTAGPSKHQ EECEEECCCCCCHHH	23.39	19880383
383	Phosphorylation	FQNTAGPSKHQAVAL EECCCCCCHHHHEEE	41.68	19880383
483	Phosphorylation	KCRIGATSDLQSVKG EEECCCCCCHHHCCC	35.47	19880383
487	Phosphorylation	GATSDLQSVKGSFPT CCCCCHHHCCCCCCC	32.85	19880383

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of PME3_ARATH !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of PME3_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of PME3_ARATH !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
PME7_ARATH	AT1G02810	physical	26183897

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of PME3_ARATH

Related Literatures of Post-Translational Modification