PMA6_ARATH - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: PMA6_ARATH
• UniProt AC: Q9SH76
• Protein Name: ATPase 6, plasma membrane-type
• Gene Name: AHA6
• Organism: Arabidopsis thaliana (Mouse-ear cress).
• Sequence Length: 949
• Subcellular Localization: Membrane; Multi-pass membrane protein.
• Protein Description: The plasma membrane H(+) ATPase of plants and fungi generates a proton gradient that drives the active transport of nutrients by H(+)-symport. The resulting external acidification and/or internal alkinization may mediate growth responses (By similarity)..
• Protein Sequence: MAADISWDEIKKENVDLEKIPVDEVFQQLKCSREGLSSEEGRNRLQIFGANKLEEKVENKFLKFLGFMWNPLSWVMEAAAIMAIVLANGGGRPPDWQDFVGITCLLIINSTISFIEENNAGNAAAALMANLAPKTKVLRDGRWGEQEAAILVPGDLISIKLGDIVPADARLLEGDPLKIDQSALTGESLPATKHQGDEVFSGSTCKQGEIEAVVIATGVHTFFGKAAHLVDSTNNVGHFQKVLTAIGNFCICSIGIGMLIEIIIMYPIQHRKYRDGIDNLLVLLIGGIPIAMPTVLSVTMAIGSHRLSQQGAITKRMTAIEEMAGMDVLCSDKTGTLTLNKLTVDKNLIEVFSKDVDKDYVILLSARASRVENQDAIDTSIVNMLGDPKEARAGITEVHFLPFNPVEKRTAITYIDTNGEWHRCSKGAPEQIIELCDLKGETKRRAHEIIDKFAERGLRSLGVARQRVPEKDKESAGTPWEFVGLLPLFDPPRHDSAETIRRALDLGVNVKMITGDQLAIGKETGRRLGMGTNMYPSSSLLENKDDTTGGVPVDELIEKADGFAGVFPEHKYEIVRKLQERKHIVGMTGDGVNDAPALKKADIGIAVDDATDAARSASDIVLTEPGLSVIVSAVLTSRAIFQRMKNYTIYAVSITIRIVLGFMLVALIWEFDFSPFMVLIIAILNDGTIMTISKDRVKPSPIPDSWKLKEIFATGVVLGTYMALVTVVFFWLAHDTTFFSDKFGVRSLQGKDEELIAVLYLQVSIISQALIFVTRSRSWSFVERPGLLLLIAFFVAQLIATLIATYAHWEFARIKGCGWGWCGVIWIYSIVTYIPLDILKFITRYTLSGKAWNNMIENRTAFTTKKDYGRGEREAQWALAQRTLHGLKPPESMFEDTATYTELSEIAEQAKKRAEVARLREVHTLKGHVESVVKLKGLDIDNLNQHYTV

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
294	Phosphorylation	GIPIAMPTVLSVTMA CCCCCCHHHHHHHHH	22.46	15308754
304	Phosphorylation	SVTMAIGSHRLSQQG HHHHHHCCHHHHHCC	10.18	29797451
318	Phosphorylation	GAITKRMTAIEEMAG CCHHHHHHHHHHHHC	28.63	19880383
331	Phosphorylation	AGMDVLCSDKTGTLT HCCCEEECCCCCEEE	37.67	19880383
514	Phosphorylation	GVNVKMITGDQLAIG CCCEEEECCCCEEEC	31.07	17317660
883	Phosphorylation	QWALAQRTLHGLKPP HHHHHHHHHCCCCCC	15.83	-
904	Phosphorylation	TATYTELSEIAEQAK CCHHHHHHHHHHHHH	22.26	17317660
931	Phosphorylation	TLKGHVESVVKLKGL HHCCHHHEEEEECCC	30.99	17483306
948	Phosphorylation	DNLNQHYTV------ CCCCCCCCC------	20.02	27531888

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of PMA6_ARATH !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of PMA6_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of PMA6_ARATH !!

Protein-Protein Interaction

Oops, there are no PPI records of PMA6_ARATH !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.