PLVAP_MOUSE - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: PLVAP_MOUSE
• UniProt AC: Q91VC4
• Protein Name: Plasmalemma vesicle-associated protein
• Gene Name: Plvap
• Organism: Mus musculus (Mouse).
• Sequence Length: 438
• Subcellular Localization: Cell membrane ; Single-pass type II membrane protein . Membrane, caveola ; Single-pass type II membrane protein . Cytoplasm, perinuclear region . Membrane-associated protein of caveolae. Found in fenestral and stomatal diaphragms in fenestrated endot
• Protein Description: Involved in the formation of stomatal and fenestral diaphragms of caveolae. May function in microvascular permeability (By similarity)..
• Protein Sequence: MGLSMDRSPYARTGDQQRGCWYYLRYFFLFVSLIQFLIILGLVLFMIYGNVHATTESSLRATEIRADSLYSQVVGLSASQANLSKQLNISLLVKETVMQQLLTTRREMERINASFRQCQGDLITYINYNRFIAAIILSEKQCQEQLKEVNKTCEALLFKLGEKVKTLEMEVAKEKAVCSKDKESLLAGKRQTEEQLEACGKARERQQQEQQVTEENLRKVQSLCIPLDQEKFQADVLSAWRDSLIYRTLETLPYHYQLMPEYASLRRTCESLPGIMTTKIEELARGLRAGIERVTRENAELRRQKLELERAAQAAQEARARAGTEAQARETQLRAECARQTQLALEEKAALRAQRDNLERELEARKRELEQLRTEVDVRISALDTCVKAKSLPAVPPRVSGPPPNPPPIDPASLEEFKKRILESQRLPVVNPAAQPSG

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
4	Phosphorylation	----MGLSMDRSPYA ----CCCCCCCCCCC	16.95	27149854
82	N-linked_Glycosylation	GLSASQANLSKQLNI CCCHHHHHHHHHHCH	36.89	-
88	N-linked_Glycosylation	ANLSKQLNISLLVKE HHHHHHHCHHHHHHH	21.22	-
112	N-linked_Glycosylation	RREMERINASFRQCQ HHHHHHHHHHHHHCC	35.43	-
150	N-linked_Glycosylation	QEQLKEVNKTCEALL HHHHHHHHHHHHHHH	34.70	-
224	Glutathionylation	LRKVQSLCIPLDQEK HHHHHHHHEECCHHH	3.49	24333276
269	Glutathionylation	YASLRRTCESLPGIM HHHHHHHHHHCCCCC	2.95	24333276
374	Phosphorylation	RELEQLRTEVDVRIS HHHHHHHHHHHHHHH	49.29	-
391	Phosphorylation	DTCVKAKSLPAVPPR HHHHHHCCCCCCCCC	44.43	25619855
424	Phosphorylation	FKKRILESQRLPVVN HHHHHHHHCCCCCCC	19.70	23984901

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of PLVAP_MOUSE !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of PLVAP_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of PLVAP_MOUSE !!

Protein-Protein Interaction

Oops, there are no PPI records of PLVAP_MOUSE !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.