dbPTM

PLLP_RAT - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	PLLP_RAT
UniProt AC	P47987
Protein Name	Plasmolipin
Gene Name	Pllp
Organism	Rattus norvegicus (Rat).
Sequence Length	182
Subcellular Localization	Membrane Multi-pass membrane protein .
Protein Description	Appears to be involved in myelination. Could also participate in ion transport events as addition of plasmolipin to lipid bilayers induces the formation of ion channels, which are voltage-dependent and K(+)-selective..
Protein Sequence	MAEFPSKVSTRTSSPAQGVGASVSAMRPDLGFVRSALGVLALLQLVLGLLVWALIADTPYHLYPAYGWVMFVAVFLWLVTIVFFIIYLFQLHMKLYMVPWPLVLLVFFVAATVLYITAFVACAAAVDLTSLRGSRPYNQRSAASFFACLVMIAYGLSAFFSFQAWRGVGSNAATSQMAGGYS

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
6	Phosphorylation	--MAEFPSKVSTRTS --CCCCCCCCCCCCC	51.51	27097102
7	Ubiquitination	-MAEFPSKVSTRTSS -CCCCCCCCCCCCCC	40.20	-
9	Phosphorylation	AEFPSKVSTRTSSPA CCCCCCCCCCCCCCC	18.86	27097102
10	Phosphorylation	EFPSKVSTRTSSPAQ CCCCCCCCCCCCCCC	40.74	27097102
12	Phosphorylation	PSKVSTRTSSPAQGV CCCCCCCCCCCCCCC	33.38	27097102
13	Phosphorylation	SKVSTRTSSPAQGVG CCCCCCCCCCCCCCC	30.91	27097102
14	Phosphorylation	KVSTRTSSPAQGVGA CCCCCCCCCCCCCCC	24.52	27097102
22	Phosphorylation	PAQGVGASVSAMRPD CCCCCCCCHHHCCCC	15.63	27097102
181	Phosphorylation	TSQMAGGYS------ HHHHCCCCC------	15.41	22276854
182	Phosphorylation	SQMAGGYS------- HHHCCCCC-------	36.70	27097102

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of PLLP_RAT !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of PLLP_RAT !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of PLLP_RAT !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
Oops, there are no PPI records of PLLP_RAT !!

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of PLLP_RAT

Related Literatures of Post-Translational Modification