PLCX1_HUMAN - dbPTM
PLCX1_HUMAN - PTM Information in dbPTM
Basic Information of Protein
UniProt ID PLCX1_HUMAN
UniProt AC Q9NUJ7
Protein Name PI-PLC X domain-containing protein 1
Gene Name PLCXD1
Organism Homo sapiens (Human).
Sequence Length 323
Subcellular Localization Cytoplasm .
Protein Description
Protein Sequence MGGQVSASNSFSRLHCRNANEDWMSALCPRLWDVPLHHLSIPGSHDTMTYCLNKKSPISHEESRLLQLLNKALPCITRPVVLKWSVTQALDVTEQLDAGVRYLDLRIAHMLEGSEKNLHFVHMVYTTALVEDTLTEISEWLERHPREVVILACRNFEGLSEDLHEYLVACIKNIFGDMLCPRGEVPTLRQLWSRGQQVIVSYEDESSLRRHHELWPGVPYWWGNRVKTEALIRYLETMKSCGRPGGLFVAGINLTENLQYVLAHPSESLEKMTLPNLPRLSAWVREQCPGPGSRCTNIIAGDFIGADGFVSDVIALNQKLLWC
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure
ASA (%) Reference Orthologous
Protein Cluster
10PhosphorylationGQVSASNSFSRLHCR
CCCCCCCCCCCCCCC
23.3123312004
12PhosphorylationVSASNSFSRLHCRNA
CCCCCCCCCCCCCCC
33.4823312004
55UbiquitinationMTYCLNKKSPISHEE
HHHHCCCCCCCCHHH
61.4629967540
102PhosphorylationQLDAGVRYLDLRIAH
HHCCCCHHHHHHHHH
11.36-
166PhosphorylationLSEDLHEYLVACIKN
CCHHHHHHHHHHHHH
8.8430257219
175UbiquitinationVACIKNIFGDMLCPR
HHHHHHHHCCCCCCC
10.7033845483
227UbiquitinationYWWGNRVKTEALIRY
CCCCCCCCHHHHHHH
37.0927667366
255PhosphorylationFVAGINLTENLQYVL
EEEEEECCCCHHHHH
20.5224043423
260PhosphorylationNLTENLQYVLAHPSE
ECCCCHHHHHHCCCH
10.7024043423
266PhosphorylationQYVLAHPSESLEKMT
HHHHHCCCHHHHHCC
29.9224043423
268PhosphorylationVLAHPSESLEKMTLP
HHHCCCHHHHHCCCC
46.2824043423
273PhosphorylationSESLEKMTLPNLPRL
CHHHHHCCCCCCCHH
50.5624719451

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of PLCX1_HUMAN !!

Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of PLCX1_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10)
Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of PLCX1_HUMAN !!

Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
NMT1_HUMANNMT1physical
26186194

Drug and Disease Associations
Kegg Disease
There are no disease associations of PTM sites.
OMIM Disease
There are no disease associations of PTM sites.
Kegg Drug
There are no disease associations of PTM sites.
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of PLCX1_HUMAN

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Related Literatures of Post-Translational Modification

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