dbPTM

PKP4_MOUSE - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	PKP4_MOUSE
UniProt AC	Q68FH0
Protein Name	Plakophilin-4
Gene Name	Pkp4
Organism	Mus musculus (Mouse).
Sequence Length	1190
Subcellular Localization	Cell junction, desmosome. Cytoplasm, cytoskeleton, spindle. Cytoplasm, cytoskeleton, spindle pole. Midbody. Cell membrane Peripheral membrane protein. Associated with the pericentrosomal region in interphase and with spindle poles during mitosis. In
Protein Description	Plays a role as a regulator of Rho activity during cytokinesis. May play a role in junctional plaques (By similarity)..
Protein Sequence	MPAPEQGSLVEEGQPQTHQEAVSTGPGMEPETTATTILASVKEQELQFQRLTRELEVERQIVASQLERCRLGAESPSIASTSSTEKSFPWRSTDVPNPGVSKPRVSDTIHPNNYLIRTEPEQGTLYSPEQTSLHESEGSLGNSRSSTQMNSYSDSGYQEAGSFHNSQTVNKADSRQHPFTGSTSNHVVRTSRAEGQTLVQPSVANRAMRRVSSVPSRAQSPSYVTSTGVSPSRGSLRTSLGSGFGSPSVTDSRPLNPSAYSSSTLPAQRAASPYSQRPASPTAVRRVGSVTSRQTSNPNGPVPQYQTTTRVGSPLTLTDAQTRVASPSQGQVGSSSPKRSGMTAVPQHLGPSLQRTVHDMDQFGQQQYDIYERMVPPRPDSLTGLRSSYASQHSQLGQELRSAVSPDLHITPIYEGRTYYSPVYRSPNHGTVELQGSQTALYRTGSVGIGNLQRTSSQRSTLTYQRNNYALNTAATYAEPYRPVQYRVQECSYNRLQHTGPADDGATRSPSIDSIQKDPREFAWRDPELPEVIHMLQHQFPSVQANAAAYLQHLCFGDNKVKMEVYRLGGIKHLVDLLDHRVLEVQKNACGALRNLVFGKSTDENKIAMKNVGGIPALLRLLRKSIDAEVRELVTGVLWNLSSCDAVKMTIIRDALSTLTNTVIVPHSGWNNSSFDDDHKIKFQTSLVLRNTTGCLRNLSSAGEEARKQMRSCEGLVDSLLYVIHTCVNTSDYDSKTVENCVCTLRNLSYRLELEVPQARLLGLNELDDLLGKESPSKDSEPSCWGKKKKKKKRTPQEDQWDGVGPIPGLSKSPKGVEMLWHPSVVKPYLTLLAESSNPATLEGSAGSLQNLSAGNWKFAAYIRAAVRKEKGLPILVELLRMDNDRVVSSVATALRNMALDVRNKELIGKYAMRDLVNRLPGGNGPSILSDETVAAICCALHEVTSKNMENAKALADSGGIEKLVNITKGRGDRSSLKVVKAAAQVLNTLWQYRDLRSIYKKDGWNQNHFITPVSTLERDRFKSHPSLSTTNQQMSPIIQSVGSTSSSPALLGIREPRSEYDRTQPPMQYYNSQGDTTHKGLYPGSSKPSPIYISSYSSPAREQNRRLQHQQLYYQDDSTRKTLDAYRLYLQSPRSYEDPYCDDRVHFPASTDYSTQYGLKSTTNYVDFYSTKRPSYRAEQYPGSPDSWV

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
75	Phosphorylation	RCRLGAESPSIASTS HHCCCCCCCCCCCCC	24.34	26824392
77	Phosphorylation	RLGAESPSIASTSST CCCCCCCCCCCCCCC	39.81	25619855
80	Phosphorylation	AESPSIASTSSTEKS CCCCCCCCCCCCCCC	27.44	25619855
81	Phosphorylation	ESPSIASTSSTEKSF CCCCCCCCCCCCCCC	20.06	25619855
82	Phosphorylation	SPSIASTSSTEKSFP CCCCCCCCCCCCCCC	32.54	25619855
83	Phosphorylation	PSIASTSSTEKSFPW CCCCCCCCCCCCCCC	40.45	25619855
84	Phosphorylation	SIASTSSTEKSFPWR CCCCCCCCCCCCCCC	47.39	25619855
87	Phosphorylation	STSSTEKSFPWRSTD CCCCCCCCCCCCCCC	30.24	19060867
106	Phosphorylation	GVSKPRVSDTIHPNN CCCCCCCCCCCCCCC	30.25	27180971
108	Phosphorylation	SKPRVSDTIHPNNYL CCCCCCCCCCCCCEE	17.43	21183079
114	Phosphorylation	DTIHPNNYLIRTEPE CCCCCCCEEEEECCC	15.33	29514104
118	Phosphorylation	PNNYLIRTEPEQGTL CCCEEEEECCCCCCC	49.23	27087446
124	Phosphorylation	RTEPEQGTLYSPEQT EECCCCCCCCCCCCC	23.40	23984901
126	Phosphorylation	EPEQGTLYSPEQTSL CCCCCCCCCCCCCCC	23.24	23984901
127	Phosphorylation	PEQGTLYSPEQTSLH CCCCCCCCCCCCCCC	25.69	19060867
131	Phosphorylation	TLYSPEQTSLHESEG CCCCCCCCCCCCCCC	31.43	19060867
132	Phosphorylation	LYSPEQTSLHESEGS CCCCCCCCCCCCCCC	27.68	27087446
136	Phosphorylation	EQTSLHESEGSLGNS CCCCCCCCCCCCCCC	36.19	27087446
139	Phosphorylation	SLHESEGSLGNSRSS CCCCCCCCCCCCCCC	29.11	27087446
143	Phosphorylation	SEGSLGNSRSSTQMN CCCCCCCCCCCCCCC	31.57	29472430
145	Phosphorylation	GSLGNSRSSTQMNSY CCCCCCCCCCCCCCC	37.24	21082442
147	Phosphorylation	LGNSRSSTQMNSYSD CCCCCCCCCCCCCCC	32.84	22817900
157	Phosphorylation	NSYSDSGYQEAGSFH CCCCCCCCCCCCCCC	13.71	29514104
180	O-linked_Glycosylation	DSRQHPFTGSTSNHV CCCCCCCCCCCCCEE	34.37	55413397
182	Phosphorylation	RQHPFTGSTSNHVVR CCCCCCCCCCCEEEE	26.13	29899451
183	O-linked_Glycosylation	QHPFTGSTSNHVVRT CCCCCCCCCCEEEEE	34.59	55413381
197	Phosphorylation	TSRAEGQTLVQPSVA ECCCCCCCCCCHHHH	39.49	22817900
202	Phosphorylation	GQTLVQPSVANRAMR CCCCCCHHHHHHHHH	19.44	22817900
212	Phosphorylation	NRAMRRVSSVPSRAQ HHHHHHHHCCCCCCC	24.65	22817900
213	Phosphorylation	RAMRRVSSVPSRAQS HHHHHHHCCCCCCCC	34.88	27149854
216	Phosphorylation	RRVSSVPSRAQSPSY HHHHCCCCCCCCCCE	37.78	24759943
217	Dimethylation	RVSSVPSRAQSPSYV HHHCCCCCCCCCCEE	30.49	-
217	Methylation	RVSSVPSRAQSPSYV HHHCCCCCCCCCCEE	30.49	54541153
220	Phosphorylation	SVPSRAQSPSYVTST CCCCCCCCCCEEEEC	18.15	25521595
222	Phosphorylation	PSRAQSPSYVTSTGV CCCCCCCCEEEECCC	37.17	24925903
223	Phosphorylation	SRAQSPSYVTSTGVS CCCCCCCEEEECCCC	15.90	25619855
225	O-linked_Glycosylation	AQSPSYVTSTGVSPS CCCCCEEEECCCCCC	16.61	22645316
225	Phosphorylation	AQSPSYVTSTGVSPS CCCCCEEEECCCCCC	16.61	25619855
226	O-linked_Glycosylation	QSPSYVTSTGVSPSR CCCCEEEECCCCCCC	17.08	22645316
226	Phosphorylation	QSPSYVTSTGVSPSR CCCCEEEECCCCCCC	17.08	25619855
227	Phosphorylation	SPSYVTSTGVSPSRG CCCEEEECCCCCCCC	32.03	25619855
230	Phosphorylation	YVTSTGVSPSRGSLR EEEECCCCCCCCCCC	20.64	25521595
232	Phosphorylation	TSTGVSPSRGSLRTS EECCCCCCCCCCCHH	41.59	24925903
233	Dimethylation	STGVSPSRGSLRTSL ECCCCCCCCCCCHHC	41.95	-
233	Methylation	STGVSPSRGSLRTSL ECCCCCCCCCCCHHC	41.95	54541157
235	Phosphorylation	GVSPSRGSLRTSLGS CCCCCCCCCCHHCCC	17.36	27149854
238	Phosphorylation	PSRGSLRTSLGSGFG CCCCCCCHHCCCCCC	33.33	26643407
239	Phosphorylation	SRGSLRTSLGSGFGS CCCCCCHHCCCCCCC	25.05	26643407
242	Phosphorylation	SLRTSLGSGFGSPSV CCCHHCCCCCCCCCC	35.92	26643407
246	Phosphorylation	SLGSGFGSPSVTDSR HCCCCCCCCCCCCCC	16.25	26643407
248	Phosphorylation	GSGFGSPSVTDSRPL CCCCCCCCCCCCCCC	39.07	26643407
250	Phosphorylation	GFGSPSVTDSRPLNP CCCCCCCCCCCCCCH	32.37	26643407
252	Phosphorylation	GSPSVTDSRPLNPSA CCCCCCCCCCCCHHH	26.82	24925903
253	Methylation	SPSVTDSRPLNPSAY CCCCCCCCCCCHHHC	42.40	24129315
269	Methylation	SSTLPAQRAASPYSQ CCCCCCHHCCCCCCC	33.94	24129315
272	Phosphorylation	LPAQRAASPYSQRPA CCCHHCCCCCCCCCC	24.32	25521595
274	Phosphorylation	AQRAASPYSQRPASP CHHCCCCCCCCCCCC	18.23	24925903
275	Phosphorylation	QRAASPYSQRPASPT HHCCCCCCCCCCCCC	24.09	24925903
280	Phosphorylation	PYSQRPASPTAVRRV CCCCCCCCCCCHHHC	26.01	25521595
282	Phosphorylation	SQRPASPTAVRRVGS CCCCCCCCCHHHCCC	34.98	24925903
289	Phosphorylation	TAVRRVGSVTSRQTS CCHHHCCCCCCCCCC	21.26	27149854
291	Phosphorylation	VRRVGSVTSRQTSNP HHHCCCCCCCCCCCC	21.64	25521595
292	Phosphorylation	RRVGSVTSRQTSNPN HHCCCCCCCCCCCCC	21.89	20139300
305	Phosphorylation	PNGPVPQYQTTTRVG CCCCCCCCEEEECCC	11.19	22817900
307	Phosphorylation	GPVPQYQTTTRVGSP CCCCCCEEEECCCCC	25.79	21183079
308	Phosphorylation	PVPQYQTTTRVGSPL CCCCCEEEECCCCCE	9.33	21183079
309	Phosphorylation	VPQYQTTTRVGSPLT CCCCEEEECCCCCEE	27.09	24759943
313	Phosphorylation	QTTTRVGSPLTLTDA EEEECCCCCEEECCC	17.55	24925903
316	Phosphorylation	TRVGSPLTLTDAQTR ECCCCCEEECCCCCC	30.88	24925903
318	Phosphorylation	VGSPLTLTDAQTRVA CCCCEEECCCCCCCC	24.85	24925903
326	Phosphorylation	DAQTRVASPSQGQVG CCCCCCCCCCCCCCC	23.40	25521595
328	Phosphorylation	QTRVASPSQGQVGSS CCCCCCCCCCCCCCC	44.43	25521595
334	Phosphorylation	PSQGQVGSSSPKRSG CCCCCCCCCCCCCCC	28.87	25521595
335	Phosphorylation	SQGQVGSSSPKRSGM CCCCCCCCCCCCCCC	44.74	25521595
336	Phosphorylation	QGQVGSSSPKRSGMT CCCCCCCCCCCCCCC	35.82	25521595
368	Phosphorylation	DQFGQQQYDIYERMV HHHHHHHHCHHHHCC	10.44	22817900
371	Phosphorylation	GQQQYDIYERMVPPR HHHHHCHHHHCCCCC	8.45	29899451
381	Phosphorylation	MVPPRPDSLTGLRSS CCCCCCCCCHHHHHH	30.43	28978645
383	Phosphorylation	PPRPDSLTGLRSSYA CCCCCCCHHHHHHHH	37.81	29899451
387	Phosphorylation	DSLTGLRSSYASQHS CCCHHHHHHHHHHHH	32.51	22817900
388	Phosphorylation	SLTGLRSSYASQHSQ CCHHHHHHHHHHHHH	20.48	22817900
389	Phosphorylation	LTGLRSSYASQHSQL CHHHHHHHHHHHHHH	16.12	22324799
391	Phosphorylation	GLRSSYASQHSQLGQ HHHHHHHHHHHHHHH	21.86	22324799
394	Phosphorylation	SSYASQHSQLGQELR HHHHHHHHHHHHHHH	21.33	22324799
402	Phosphorylation	QLGQELRSAVSPDLH HHHHHHHHHHCCCCC	45.72	25521595
405	Phosphorylation	QELRSAVSPDLHITP HHHHHHHCCCCCCCC	16.65	25521595
411	Phosphorylation	VSPDLHITPIYEGRT HCCCCCCCCCCCCCE	7.90	25521595
414	Phosphorylation	DLHITPIYEGRTYYS CCCCCCCCCCCEEEE	17.34	27180971
418	Phosphorylation	TPIYEGRTYYSPVYR CCCCCCCEEEECCCC	37.35	22817900
419	Phosphorylation	PIYEGRTYYSPVYRS CCCCCCEEEECCCCC	10.69	19060867
420	Phosphorylation	IYEGRTYYSPVYRSP CCCCCEEEECCCCCC	13.09	25521595
421	Phosphorylation	YEGRTYYSPVYRSPN CCCCEEEECCCCCCC	9.47	22817900
424	Phosphorylation	RTYYSPVYRSPNHGT CEEEECCCCCCCCCE	14.57	22817900
426	Phosphorylation	YYSPVYRSPNHGTVE EEECCCCCCCCCEEE	16.62	22817900
431	Phosphorylation	YRSPNHGTVELQGSQ CCCCCCCEEEECCCE	11.85	22817900
437	Phosphorylation	GTVELQGSQTALYRT CEEEECCCEEEEEEE	16.05	27742792
439	Phosphorylation	VELQGSQTALYRTGS EEECCCEEEEEEECC	21.96	19060867
442	Phosphorylation	QGSQTALYRTGSVGI CCCEEEEEEECCCCC	12.03	22817900
444	Phosphorylation	SQTALYRTGSVGIGN CEEEEEEECCCCCCC	21.91	22324799
446	Phosphorylation	TALYRTGSVGIGNLQ EEEEEECCCCCCCCC	19.29	25521595
455	Phosphorylation	GIGNLQRTSSQRSTL CCCCCCCCCCCCCEE	21.55	22817900
456	Phosphorylation	IGNLQRTSSQRSTLT CCCCCCCCCCCCEEE	27.02	23737553
457	Phosphorylation	GNLQRTSSQRSTLTY CCCCCCCCCCCEEEE	29.06	23737553
460	Phosphorylation	QRTSSQRSTLTYQRN CCCCCCCCEEEEECC	21.82	23737553
461	Phosphorylation	RTSSQRSTLTYQRNN CCCCCCCEEEEECCC	25.88	23737553
464	Phosphorylation	SQRSTLTYQRNNYAL CCCCEEEEECCCEEC	14.48	29899451
469	Phosphorylation	LTYQRNNYALNTAAT EEEECCCEECCCCCC	18.93	22499769
473	Phosphorylation	RNNYALNTAATYAEP CCCEECCCCCCCCCC	20.65	22499769
476	Phosphorylation	YALNTAATYAEPYRP EECCCCCCCCCCCCC	22.32	22499769
477	Phosphorylation	ALNTAATYAEPYRPV ECCCCCCCCCCCCCC	12.30	18515860
481	Phosphorylation	AATYAEPYRPVQYRV CCCCCCCCCCCEEEE	21.03	22499769
486	Phosphorylation	EPYRPVQYRVQECSY CCCCCCEEEEEECCC	17.00	22499769
493	Phosphorylation	YRVQECSYNRLQHTG EEEEECCCCCCCCCC	18.89	29514104
499	Phosphorylation	SYNRLQHTGPADDGA CCCCCCCCCCCCCCC	31.72	29472430
507	Phosphorylation	GPADDGATRSPSIDS CCCCCCCCCCCCHHH	36.89	22324799
509	Phosphorylation	ADDGATRSPSIDSIQ CCCCCCCCCCHHHHC	20.74	25521595
511	Phosphorylation	DGATRSPSIDSIQKD CCCCCCCCHHHHCCC	40.03	25521595
514	Phosphorylation	TRSPSIDSIQKDPRE CCCCCHHHHCCCHHH	25.83	25521595
517	Ubiquitination	PSIDSIQKDPREFAW CCHHHHCCCHHHHHC	68.94	22790023
587	Ubiquitination	HRVLEVQKNACGALR HHHHHHHHHHHHHHH	52.25	22790023
600	Ubiquitination	LRNLVFGKSTDENKI HHHHHHCCCCCCCHH	38.42	22790023
601	Phosphorylation	RNLVFGKSTDENKIA HHHHHCCCCCCCHHC	41.28	29895711
668	Phosphorylation	NTVIVPHSGWNNSSF CEEEECCCCCCCCCC	39.16	29899451
673	Phosphorylation	PHSGWNNSSFDDDHK CCCCCCCCCCCCCCC	29.21	29899451
674	Phosphorylation	HSGWNNSSFDDDHKI CCCCCCCCCCCCCCC	34.51	29899451
680	Ubiquitination	SSFDDDHKIKFQTSL CCCCCCCCCEEEEEH	55.36	22790023
682	Ubiquitination	FDDDHKIKFQTSLVL CCCCCCCEEEEEHHH	35.90	22790023
773	Ubiquitination	ELDDLLGKESPSKDS HHHHHCCCCCCCCCC	55.79	22790023
775	Phosphorylation	DDLLGKESPSKDSEP HHHCCCCCCCCCCCC	37.65	25521595
777	Phosphorylation	LLGKESPSKDSEPSC HCCCCCCCCCCCCCC	59.37	21149613
780	Phosphorylation	KESPSKDSEPSCWGK CCCCCCCCCCCCCCC	55.96	23984901
783	Phosphorylation	PSKDSEPSCWGKKKK CCCCCCCCCCCCCCC	20.60	23984901
889	Phosphorylation	MDNDRVVSSVATALR CCCHHHHHHHHHHHH	19.08	21454597
890	Phosphorylation	DNDRVVSSVATALRN CCHHHHHHHHHHHHH	12.26	-
893	Phosphorylation	RVVSSVATALRNMAL HHHHHHHHHHHHHHH	24.86	21454597
910	Ubiquitination	RNKELIGKYAMRDLV CCHHHHHHHHHHHHH	23.89	22790023
953	Acetylation	SKNMENAKALADSGG HCCHHHHHHHHHCCC	56.36	6569581
963	Ubiquitination	ADSGGIEKLVNITKG HHCCCHHHHHHCCCC	56.68	22790023
1012	Phosphorylation	WNQNHFITPVSTLER CCCCCEECCCHHHCH	19.39	25521595
1015	Phosphorylation	NHFITPVSTLERDRF CCEECCCHHHCHHHH	28.60	25521595
1016	Phosphorylation	HFITPVSTLERDRFK CEECCCHHHCHHHHH	32.64	25521595
1024	Phosphorylation	LERDRFKSHPSLSTT HCHHHHHCCCCCCCC	37.61	20415495
1024 (in isoform 2)	Phosphorylation	-	37.61	29472430
1027	Phosphorylation	DRFKSHPSLSTTNQQ HHHHCCCCCCCCCCC	29.54	20415495
1027 (in isoform 2)	Phosphorylation	-	29.54	29472430
1029	Phosphorylation	FKSHPSLSTTNQQMS HHCCCCCCCCCCCCC	37.21	20415495
1029 (in isoform 2)	Phosphorylation	-	37.21	29472430
1030	Phosphorylation	KSHPSLSTTNQQMSP HCCCCCCCCCCCCCH	34.75	20415495
1030 (in isoform 2)	Phosphorylation	-	34.75	29472430
1031	Phosphorylation	SHPSLSTTNQQMSPI CCCCCCCCCCCCCHH	27.88	20415495
1031 (in isoform 2)	Phosphorylation	-	27.88	29472430
1036	Phosphorylation	STTNQQMSPIIQSVG CCCCCCCCHHHHHHC	14.49	22817900
1036 (in isoform 2)	Phosphorylation	-	14.49	29472430
1041	Phosphorylation	QMSPIIQSVGSTSSS CCCHHHHHHCCCCCC	20.31	19060867
1041 (in isoform 2)	Phosphorylation	-	20.31	29472430
1043 (in isoform 2)	Phosphorylation	-	30.38	29472430
1044	Phosphorylation	PIIQSVGSTSSSPAL HHHHHHCCCCCCCCC	23.98	22817900
1045	Phosphorylation	IIQSVGSTSSSPALL HHHHHCCCCCCCCCC	27.05	22817900
1045 (in isoform 2)	Ubiquitination	-	27.05	-
1046	Phosphorylation	IQSVGSTSSSPALLG HHHHCCCCCCCCCCC	30.43	19060867
1047	Phosphorylation	QSVGSTSSSPALLGI HHHCCCCCCCCCCCC	40.19	29899451
1048	Phosphorylation	SVGSTSSSPALLGIR HHCCCCCCCCCCCCC	17.60	29899451
1086	Phosphorylation	HKGLYPGSSKPSPIY CCCCCCCCCCCCCEE	30.59	24925903
1087	O-linked_Glycosylation	KGLYPGSSKPSPIYI CCCCCCCCCCCCEEE	55.27	22645316
1087	Phosphorylation	KGLYPGSSKPSPIYI CCCCCCCCCCCCEEE	55.27	24925903
1088	Ubiquitination	GLYPGSSKPSPIYIS CCCCCCCCCCCEEEE	51.73	22790023
1090	Phosphorylation	YPGSSKPSPIYISSY CCCCCCCCCEEEECC	27.89	25521595
1093	Phosphorylation	SSKPSPIYISSYSSP CCCCCCEEEECCCCC	9.72	24925903
1095	Phosphorylation	KPSPIYISSYSSPAR CCCCEEEECCCCCHH	13.27	25521595
1096	Phosphorylation	PSPIYISSYSSPARE CCCEEEECCCCCHHH	21.34	22324799
1097	Phosphorylation	SPIYISSYSSPAREQ CCEEEECCCCCHHHH	13.33	24925903
1098	Phosphorylation	PIYISSYSSPAREQN CEEEECCCCCHHHHH	31.62	22324799
1099	Phosphorylation	IYISSYSSPAREQNR EEEECCCCCHHHHHH	17.85	22324799
1114	Phosphorylation	RLQHQQLYYQDDSTR HHHHHHEECCCCCCC	8.51	29514104
1115	Phosphorylation	LQHQQLYYQDDSTRK HHHHHEECCCCCCCH	17.66	-
1119	Phosphorylation	QLYYQDDSTRKTLDA HEECCCCCCCHHHHH	38.10	29899451
1122	Ubiquitination	YQDDSTRKTLDAYRL CCCCCCCHHHHHHHH	54.23	22790023
1127	Phosphorylation	TRKTLDAYRLYLQSP CCHHHHHHHHHHCCC	10.79	22817900
1130	Phosphorylation	TLDAYRLYLQSPRSY HHHHHHHHHCCCCCC	8.16	22817900
1133	Phosphorylation	AYRLYLQSPRSYEDP HHHHHHCCCCCCCCC	21.49	24925903
1136	Phosphorylation	LYLQSPRSYEDPYCD HHHCCCCCCCCCCCC	35.94	25521595
1137	Phosphorylation	YLQSPRSYEDPYCDD HHCCCCCCCCCCCCC	26.15	22499769
1141	Phosphorylation	PRSYEDPYCDDRVHF CCCCCCCCCCCCCCC	22.34	22499769
1152	O-linked_Glycosylation	RVHFPASTDYSTQYG CCCCCCCCCCCCCCC	40.85	8502753
1152	Phosphorylation	RVHFPASTDYSTQYG CCCCCCCCCCCCCCC	40.85	22817900
1154	Phosphorylation	HFPASTDYSTQYGLK CCCCCCCCCCCCCCC	17.44	-
1156	Phosphorylation	PASTDYSTQYGLKST CCCCCCCCCCCCCCC	21.41	-
1161	Ubiquitination	YSTQYGLKSTTNYVD CCCCCCCCCCCCCCC	41.20	22790023
1162	Phosphorylation	STQYGLKSTTNYVDF CCCCCCCCCCCCCCC	45.57	22499769
1163	Phosphorylation	TQYGLKSTTNYVDFY CCCCCCCCCCCCCCC	19.92	22499769
1164	Phosphorylation	QYGLKSTTNYVDFYS CCCCCCCCCCCCCCC	31.48	22499769
1166	Phosphorylation	GLKSTTNYVDFYSTK CCCCCCCCCCCCCCC	10.17	22499769
1170	Phosphorylation	TTNYVDFYSTKRPSY CCCCCCCCCCCCCCC	15.80	22499769
1171	Phosphorylation	TNYVDFYSTKRPSYR CCCCCCCCCCCCCCC	27.69	27841257
1172	Phosphorylation	NYVDFYSTKRPSYRA CCCCCCCCCCCCCCC	21.50	-
1173	Ubiquitination	YVDFYSTKRPSYRAE CCCCCCCCCCCCCCH	57.27	22790023
1176	Phosphorylation	FYSTKRPSYRAEQYP CCCCCCCCCCCHHCC	31.14	23375375
1182	Phosphorylation	PSYRAEQYPGSPDSW CCCCCHHCCCCCCCC	10.89	24759943
1185	Phosphorylation	RAEQYPGSPDSWV-- CCHHCCCCCCCCC--	22.49	22324799
1188	Phosphorylation	QYPGSPDSWV----- HCCCCCCCCC-----	32.87	22324799

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of PKP4_MOUSE !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of PKP4_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of PKP4_MOUSE !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
Oops, there are no PPI records of PKP4_MOUSE !!

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of PKP4_MOUSE

Related Literatures of Post-Translational Modification

Phosphorylation
Reference	PubMed
"Large-scale phosphorylation analysis of mouse liver."; Villen J., Beausoleil S.A., Gerber S.A., Gygi S.P.; Proc. Natl. Acad. Sci. U.S.A. 104:1488-1493(2007). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-132; SER-272; TYR-274;SER-280 AND SER-446, AND MASS SPECTROMETRY.	17242355 [Abstract]
"Qualitative and quantitative analyses of protein phosphorylation innaive and stimulated mouse synaptosomal preparations."; Munton R.P., Tweedie-Cullen R., Livingstone-Zatchej M., Weinandy F.,Waidelich M., Longo D., Gehrig P., Potthast F., Rutishauser D.,Gerrits B., Panse C., Schlapbach R., Mansuy I.M.; Mol. Cell. Proteomics 6:283-293(2007). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-220; THR-225; SER-230;SER-232; SER-313; SER-335; SER-336; SER-405 AND SER-1136, AND MASSSPECTROMETRY.	17114649 [Abstract]
"Comprehensive identification of phosphorylation sites in postsynapticdensity preparations."; Trinidad J.C., Specht C.G., Thalhammer A., Schoepfer R.,Burlingame A.L.; Mol. Cell. Proteomics 5:914-922(2006). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-289; SER-313; SER-405;SER-421 AND SER-1133, AND MASS SPECTROMETRY.	16452087 [Abstract]
"Proteomic analysis of in vivo phosphorylated synaptic proteins."; Collins M.O., Yu L., Coba M.P., Husi H., Campuzano I.,Blackstock W.P., Choudhary J.S., Grant S.G.; J. Biol. Chem. 280:5972-5982(2005). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-509; SER-511; SER-514;SER-1047 AND SER-1048, AND MASS SPECTROMETRY.	15572359 [Abstract]
"Large-scale identification and evolution indexing of tyrosinephosphorylation sites from murine brain."; Ballif B.A., Carey G.R., Sunyaev S.R., Gygi S.P.; J. Proteome Res. 7:311-318(2008). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT TYR-371 AND TYR-477, ANDMASS SPECTROMETRY.	18034455 [Abstract]