PKNX2_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: PKNX2_HUMAN
• UniProt AC: Q96KN3
• Protein Name: Homeobox protein PKNOX2
• Gene Name: PKNOX2
• Organism: Homo sapiens (Human).
• Sequence Length: 472
• Subcellular Localization: Nucleus .
• Protein Sequence: MMQHASPAPALTMMATQNVPPPPYQDSPQMTATAQPPSKAQAVHISAPSAAASTPVPSAPIDPQAQLEADKRAVYRHPLFPLLTLLFEKCEQATQGSECITSASFDVDIENFVHQQEQEHKPFFSDDPELDNLMVKAIQVLRIHLLELEKVNELCKDFCNRYITCLKTKMHSDNLLRNDLGGPYSPNQPSINLHSQDLLQNSPNSMSGVSNNPQGIVVPASALQQGNIAMTTVNSQVVSGGALYQPVTMVTSQGQVVTQAIPQGAIQIQNTQVNLDLTSLLDNEDKKSKNKRGVLPKHATNIMRSWLFQHLMHPYPTEDEKRQIAAQTNLTLLQVNNWFINARRRILQPMLDASNPDPAPKAKKIKSQHRPTQRFWPNSIAAGVLQQQGGAPGTNPDGSINLDNLQSLSSDSATMAMQQAMMAAHDDSLDGTEEEDEDEMEEEEEEELEEEVDELQTTNVSDLGLEHSDSLE

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
46	Phosphorylation	KAQAVHISAPSAAAS CCCEEEEECCCHHCC	21.17	22210691
53	Phosphorylation	SAPSAAASTPVPSAP ECCCHHCCCCCCCCC	28.63	22210691
54	Phosphorylation	APSAAASTPVPSAPI CCCHHCCCCCCCCCC	24.47	22210691
289	Acetylation	DNEDKKSKNKRGVLP CCCCHHCCCCCCCCH	75.31	30591385
297	Ubiquitination	NKRGVLPKHATNIMR CCCCCCHHHHHHHHH	41.53	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of PKNX2_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of PKNX2_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of PKNX2_HUMAN !!

Protein-Protein Interaction

Oops, there are no PPI records of PKNX2_HUMAN !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.