dbPTM

PISD_CAEEL - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	PISD_CAEEL
UniProt AC	Q10949
Protein Name	Phosphatidylserine decarboxylase proenzyme, mitochondrial {ECO:0000255\|HAMAP-Rule:MF_03208}
Gene Name	psd-1 {ECO:0000255\|HAMAP-Rule:MF_03208}
Organism	Caenorhabditis elegans.
Sequence Length	377
Subcellular Localization	Phosphatidylserine decarboxylase beta chain: Mitochondrion inner membrane Single-pass membrane protein Intermembrane side . Phosphatidylserine decarboxylase alpha chain: Mitochondrion inner membrane Peripheral membrane protein Intermembrane side
Protein Description	Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer). Plays a central role in phospholipid metabolism and in the interorganelle trafficking of phosphatidylserine..
Protein Sequence	MMPLFNVLRSARMLPAVSKKVVSPPMMLRSVRELTNQSKNVYATKEVIIGASQKKKRSWVKWLSVSTLIIGGASYVGYLFTPDWREIVDSKHYYSNWKIRVYLSLPFNTASRVIGGLANQEIPVWLREHLLGGFARMYDCRMDDCVDPDFKNYPSFAAFFNRKLKESTRPISASPLVSPADGTVLHFGKVEDNKIEYVKGHDYDVDKFLGDVDLPQKDELDLYQVVIYLAPGDYHAFHSPARWVANQCRHVPGLLLSVRPTLLSHVPHLFCLNERVVLNGSWRHGFFSMSAVAATNVGDIVVDAEPSLRTNIVRRKTQKIMNTETEIHAPYVSGERVGEFRLGSTIVLVFQAPPTIKFAIKAGDPLRYGQSLVADGV

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference	Orthologous Protein Cluster
344	Pyruvic acid (Ser)	VGEFRLGSTIVLVFQ EEEEECCCEEEEEEE	21.39	-
344	Pyruvate	VGEFRLGSTIVLVFQ EEEEECCCEEEEEEE	21.39	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of PISD_CAEEL !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of PISD_CAEEL !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of PISD_CAEEL !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
Oops, there are no PPI records of PISD_CAEEL !!

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of PISD_CAEEL

Related Literatures of Post-Translational Modification