PHS2_ARATH - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: PHS2_ARATH
• UniProt AC: Q9SD76
• Protein Name: Alpha-glucan phosphorylase 2, cytosolic
• Gene Name: PHS2
• Organism: Arabidopsis thaliana (Mouse-ear cress).
• Sequence Length: 841
• Subcellular Localization: Cytoplasm.
• Protein Description: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity)..
• Protein Sequence: MANANGKAATSLPEKISAKANPEADDATEIAGNIVYHAKYSPHFSPLKFGPEQALYATAESLRDRLIQLWNETYVHFNKVDPKQTYYLSMEYLQGRALTNAIGNLNLQGPYADALRTLGYELEEIAEQEKDAALGNGGLGRLASCFLDSMATLNLPAWGYGLRYRHGLFKQIITKKGQEEIPEDWLEKFSPWEIVRHDVVFPVRFFGKVQVNPDGSRKWVDGDVVQALAYDVPIPGYGTKNTISLRLWEAKARAEDLDLFQFNEGEYELAAQLHSRAQQICTVLYPGDATENGKLLRLKQQFFLCSASLQDIISRFHERSTTEGSRKWSEFPSKVAVQMNDTHPTLAIPELMRLLMDDNGLGWDEAWDVTSKTVAYTNHTVLPEALEKWSQSLMWKLLPRHMEIIEEIDKRFVQTIRDTRVDLEDKISSLSILDNNPQKPVVRMANLCVVSSHTVNGVAQLHSDILKAELFADYVSIWPNKFQNKTNGITPRRWLRFCSPELSDIITKWLKTDKWITDLDLLTGLRQFADNEELQSEWASAKTANKKRLAQYIERVTGVSIDPTSLFDIQVKRIHEYKRQLMNILGVVYRFKKLKEMKPEERKKTVPRTVMIGGKAFATYTNAKRIVKLVNDVGDVVNSDPEVNEYLKVVFVPNYNVTVAEMLIPGSELSQHISTAGMEASGTSNMKFALNGCLIIGTLDGANVEIREEVGEENFFLFGATADQVPRLRKEREDGLFKPDPRFEEAKQFVKSGVFGSYDYGPLLDSLEGNTGFGRGDYFLVGYDFPSYMDAQAKVDEAYKDRKGWLKMSILSTAGSGKFSSDRTIAQYAKEIWNIEACPVP

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
40	Phosphorylation	NIVYHAKYSPHFSPL HHHHEEECCCCCCCC		25561503
41	Phosphorylation	IVYHAKYSPHFSPLK HHHEEECCCCCCCCC		25561503
45	Phosphorylation	AKYSPHFSPLKFGPE EECCCCCCCCCCCHH		25561503
564	Phosphorylation	TGVSIDPTSLFDIQV HCCCCCCCCHHHHHH		19880383
565	Phosphorylation	GVSIDPTSLFDIQVK CCCCCCCCHHHHHHH		19880383
605	Phosphorylation	KPEERKKTVPRTVMI CHHHHCCCCCCEEEE		19880383
609	Phosphorylation	RKKTVPRTVMIGGKA HCCCCCCEEEECCEE		19880383
687	N6-(pyridoxal phosphate)lysine	ASGTSNMKFALNGCL CCCCCCCEEEECCEE		-
687	Other	ASGTSNMKFALNGCL CCCCCCCEEEECCEE		-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of PHS2_ARATH !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of PHS2_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of PHS2_ARATH !!

Protein-Protein Interaction

Oops, there are no PPI records of PHS2_ARATH !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.