PHS1_ARATH - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: PHS1_ARATH
• UniProt AC: Q9LIB2
• Protein Name: Alpha-glucan phosphorylase 1
• Gene Name: PHS1
• Organism: Arabidopsis thaliana (Mouse-ear cress).
• Sequence Length: 962
• Subcellular Localization: Plastid, chloroplast stroma .
• Protein Description: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity). May be not required for the degradation of starch, but the phosphorolysis of starch may play an important role in water stress tolerance..
• Protein Sequence: MDTMRISGVSTGAEVLIQCNSLSSLVSRRCDDGKWRTRMFPARNRDLRPSPTRRSFLSVKSISSEPKAKVTDAVLDSEQEVFISSMNPFAPDAASVASSIKYHAEFTPLFSPEKFELPKAFFATAQSVRDALIMNWNATYEYYNRVNVKQAYYLSMEFLQGRALSNAVGNLGLNSAYGDALKRLGFDLESVASQEPDPALGNGGLGRLASCFLDSMATLNYPAWGYGLRYKYGLFKQRITKDGQEEAAEDWLELSNPWEIVRNDVSYPIKFYGKVVFGSDGKKRWIGGEDIVAVAYDVPIPGYKTKTTINLRLWSTKAPSEDFDLSSYNSGKHTEAAEALFNAEKICFVLYPGDESTEGKALRLKQQYTLCSASLQDIVARFETRSGGNVNWEEFPEKVAVQMNDTHPTLCIPELMRILMDLKGLSWEDAWKITQRTVAYTNHTVLPEALEKWSLELMEKLLPRHVEIIEKIDEELVRTIVSEYGTADPDLLEEKLKAMRILENVELPSAFADVIVKPVNKPVTAKDAQNGVKTEQEEEKTAGEEEEDEVIPEPTVEPPKMVRMANLAVVGGHAVNGVAEIHSEIVKQDVFNDFVQLWPEKFQNKTNGVTPRRWIRFCNPYLSDIITNWIGTEDWVLNTEKVAELRKFADNEDLQSEWRAAKKKNKLKVVSLIKERTGYTVSPDAMFDIQIKRIHEYKRQLLNILGIVYRYKKMKEMSASEREKAFVPRVCIFGGKAFATYVQAKRIVKFITDVASTINHDPEIGDLLKVIFVPDYNVSVAELLIPASELSQHISTAGMEASGTSNMKFSMNGCVLIGTLDGANVEIREEVGEENFFLFGAKADQIVNLRKERAEGKFVPDPTFEEVKKFVGSGVFGSNSYDELIGSLEGNEGFGRADYFLVGKDFPSYIECQEKVDEAYRDQKRWTRMSIMNTAGSFKFSSDRTIHEYAKDIWNIKQVELP

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
21	Phosphorylation	EVLIQCNSLSSLVSR CCEEECCCHHHHHHH	43.77	24894044
23	Phosphorylation	LIQCNSLSSLVSRRC EEECCCHHHHHHHCC	19.46	24894044
279	Phosphorylation	YGKVVFGSDGKKRWI EEEEEECCCCCEEEE	2.58	25561503
534	Phosphorylation	DAQNGVKTEQEEEKT HHHCCCCCHHHHHHC	3.88	23776212
541	Phosphorylation	TEQEEEKTAGEEEED CHHHHHHCCCCCCCC	37.39	23776212
555	Phosphorylation	DEVIPEPTVEPPKMV CCCCCCCCCCCCCEE	50.00	23776212
808	N6-(pyridoxal phosphate)lysine	ASGTSNMKFSMNGCV CCCCCCCEEEECEEE	2.13	-
808	Other	ASGTSNMKFSMNGCV CCCCCCCEEEECEEE	2.13	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of PHS1_ARATH !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of PHS1_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of PHS1_ARATH !!

Protein-Protein Interaction

Oops, there are no PPI records of PHS1_ARATH !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.