dbPTM

PHLB1_HUMAN - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	PHLB1_HUMAN
UniProt AC	Q86UU1
Protein Name	Pleckstrin homology-like domain family B member 1
Gene Name	PHLDB1
Organism	Homo sapiens (Human).
Sequence Length	1377
Subcellular Localization
Protein Description
Protein Sequence	MDALNRNQIGPGCQTQTMVQKGPLDLIETGKGLKVQTDKPHLVSLGSGRLSTAITLLPLEEGRTVIGSAARDISLQGPGLAPEHCYIENLRGTLTLYPCGNACTIDGLPVRQPTRLTQGCMLCLGQSTFLRFNHPAEAKWMKSMIPAGGRAPGPPYSPVPAESESLVNGNHTPQTATRGPSACASHSSLVSSIEKDLQEIMDSLVLEEPGAAGKKPAATSPLSPMANGGRYLLSPPTSPGAMSVGSSYENTSPAFSPLSSPASSGSCASHSPSGQEPGPSVPPLVPARSSSYHLALQPPQSRPSGARSESPRLSRKGGHERPPSPGLRGLLTDSPAATVLAEARRATESPRLGGQLPVVAISLSEYPASGALSQPTSIPGSPKFQPPVPAPRNKIGTLQDRPPSPFREPPGSERVLTTSPSRQLVGRTFSDGLATRTLQPPESPRLGRRGLDSMRELPPLSPSLSRRALSPLPTRTTPDPKLNREVAESPRPRRWAAHGASPEDFSLTLGARGRRTRSPSPTLGESLAPHKGSFSGRLSPAYSLGSLTGASPCQSPCVQRKLSSGDLRVPVTRERKNSITEISDNEDDLLEYHRRQRQERLREQEMERLERQRLETILNLCAEYSRADGGPEAGELPSIGEATAALALAGRRPSRGLAGASGRSSEEPGVATQRLWESMERSDEENLKEECSSTESTQQEHEDAPSTKLQGEVLALEEERAQVLGHVEQLKVRVKELEQQLQESAREAEMERALLQGEREAERALLQKEQKAVDQLQEKLVALETGIQKERDKEAEALETETKLFEDLEFQQLERESRVEEERELAGQGLLRSKAELLRSIAKRKERLAILDSQAGQIRAQAVQESERLARDKNASLQLLQKEKEKLTVLERRYHSLTGGRPFPKTTSTLKEMEKLLLPAVDLEQWYQELMAGLGTGPAAASPHSSPPPLPAKASRQLQVYRSKMDGEATSPLPRTRSGPLPSSSGSSSSSSQLSVATLGRSPSPKSALLTQNGTGSLPRNLAATLQDIETKRQLALQQKGQQVIEEQRRRLAELKQKAAAEAQCQWDALHGAAPFPAGPSGFPPLMHHSILHHLPAGRERGEEGEHAYDTLSLESSDSMETSISTGGNSACSPDNMSSASGLDMGKIEEMEKMLKEAHAEKNRLMESREREMELRRQALEEERRRREQVERRLQSESARRQQLVEKEVKMREKQFSQARPLTRYLPIRKEDFDLKTHIESSGHGVDTCLHVVLSSKVCRGYLVKMGGKIKSWKKRWFVFDRLKRTLSYYVDKHETKLKGVIYFQAIEEVYYDHLRSAAKKRFFRFTMVTESPNPALTFCVKTHDRLYYMVAPSAEAMRIWMDVIVTGAEGYTQFMN

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
15	Phosphorylation	QIGPGCQTQTMVQKG CCCCCCCHHHHHHCC	30.04	29888752
17	Phosphorylation	GPGCQTQTMVQKGPL CCCCCHHHHHHCCCC	23.77	29888752
31	Acetylation	LDLIETGKGLKVQTD CCEEECCCCCEECCC	69.37	7408255
37	Phosphorylation	GKGLKVQTDKPHLVS CCCCEECCCCCCEEE	49.32	23312004
39	Acetylation	GLKVQTDKPHLVSLG CCEECCCCCCEEEEC	37.41	7408263
44	Phosphorylation	TDKPHLVSLGSGRLS CCCCCEEEECCCCCC	33.11	24719451
47	Phosphorylation	PHLVSLGSGRLSTAI CCEEEECCCCCCEEE	26.49	28857561
51	Phosphorylation	SLGSGRLSTAITLLP EECCCCCCEEEEEEE	17.90	26657352
52	Phosphorylation	LGSGRLSTAITLLPL ECCCCCCEEEEEEEC	27.03	29255136
68	Phosphorylation	EGRTVIGSAARDISL CCCEEECCCCCCHHC	13.97	23532336
86	Phosphorylation	GLAPEHCYIENLRGT CCCCCCEEEECCCCE	17.12	27642862
93	Phosphorylation	YIENLRGTLTLYPCG EEECCCCEEEEEECC	15.33	25693802
95	Phosphorylation	ENLRGTLTLYPCGNA ECCCCEEEEEECCCE	24.88	25693802
97	Phosphorylation	LRGTLTLYPCGNACT CCCEEEEEECCCEEE	7.40	25693802
104	Phosphorylation	YPCGNACTIDGLPVR EECCCEEEECCCCCC	21.49	25693802
131	Asymmetric dimethylarginine	LGQSTFLRFNHPAEA ECCCHHHHCCCHHHH	26.57	-
131	Methylation	LGQSTFLRFNHPAEA ECCCHHHHCCCHHHH	26.57	-
156	Phosphorylation	GRAPGPPYSPVPAES CCCCCCCCCCCCCCC	28.83	25850435
157	Phosphorylation	RAPGPPYSPVPAESE CCCCCCCCCCCCCCC	25.79	25159151
163	Phosphorylation	YSPVPAESESLVNGN CCCCCCCCCCCCCCC	34.29	25850435
165	Phosphorylation	PVPAESESLVNGNHT CCCCCCCCCCCCCCC	47.07	25850435
172	Phosphorylation	SLVNGNHTPQTATRG CCCCCCCCCCCCCCC	22.53	25159151
175	Phosphorylation	NGNHTPQTATRGPSA CCCCCCCCCCCCCCH	31.06	26425664
181	Phosphorylation	QTATRGPSACASHSS CCCCCCCCHHHCCHH	38.51	23186163
185	Phosphorylation	RGPSACASHSSLVSS CCCCHHHCCHHHHHH	24.64	28555341
187	Phosphorylation	PSACASHSSLVSSIE CCHHHCCHHHHHHHH	23.91	28857561
188	Phosphorylation	SACASHSSLVSSIEK CHHHCCHHHHHHHHH	27.63	26657352
191	Phosphorylation	ASHSSLVSSIEKDLQ HCCHHHHHHHHHHHH	30.78	25159151
192	Phosphorylation	SHSSLVSSIEKDLQE CCHHHHHHHHHHHHH	27.56	25159151
203	Phosphorylation	DLQEIMDSLVLEEPG HHHHHHHHHHHCCCC	11.73	22199227
219	Phosphorylation	AGKKPAATSPLSPMA CCCCCCCCCCCCCCC	32.74	22617229
220	Phosphorylation	GKKPAATSPLSPMAN CCCCCCCCCCCCCCC	21.08	26055452
223	Phosphorylation	PAATSPLSPMANGGR CCCCCCCCCCCCCCC	18.93	25159151
243	Phosphorylation	PTSPGAMSVGSSYEN CCCCCCCCCCCCCCC	23.85	28348404
246	Phosphorylation	PGAMSVGSSYENTSP CCCCCCCCCCCCCCC	27.82	28348404
247	Phosphorylation	GAMSVGSSYENTSPA CCCCCCCCCCCCCCC	30.45	28348404
248	Phosphorylation	AMSVGSSYENTSPAF CCCCCCCCCCCCCCC	18.20	28348404
251	Phosphorylation	VGSSYENTSPAFSPL CCCCCCCCCCCCCCC	24.93	28348404
252	Phosphorylation	GSSYENTSPAFSPLS CCCCCCCCCCCCCCC	26.30	28348404
256	Phosphorylation	ENTSPAFSPLSSPAS CCCCCCCCCCCCCCC	27.34	28348404
259	Phosphorylation	SPAFSPLSSPASSGS CCCCCCCCCCCCCCC	37.35	28348404
260	Phosphorylation	PAFSPLSSPASSGSC CCCCCCCCCCCCCCC	31.97	28348404
263	Phosphorylation	SPLSSPASSGSCASH CCCCCCCCCCCCCCC	38.32	28348404
264	Phosphorylation	PLSSPASSGSCASHS CCCCCCCCCCCCCCC	36.51	28348404
266	Phosphorylation	SSPASSGSCASHSPS CCCCCCCCCCCCCCC	14.41	28348404
269	Phosphorylation	ASSGSCASHSPSGQE CCCCCCCCCCCCCCC	28.91	28348404
271	Phosphorylation	SGSCASHSPSGQEPG CCCCCCCCCCCCCCC	20.47	28348404
273	Phosphorylation	SCASHSPSGQEPGPS CCCCCCCCCCCCCCC	57.00	28348404
289	Phosphorylation	PPLVPARSSSYHLAL CCCCCCCCCCEEEEC	26.24	23917254
290	Phosphorylation	PLVPARSSSYHLALQ CCCCCCCCCEEEECC	29.39	28348404
291	Phosphorylation	LVPARSSSYHLALQP CCCCCCCCEEEECCC	20.16	23917254
292	Phosphorylation	VPARSSSYHLALQPP CCCCCCCEEEECCCC	11.64	28555341
301	Phosphorylation	LALQPPQSRPSGARS EECCCCCCCCCCCCC	52.51	28555341
308	Phosphorylation	SRPSGARSESPRLSR CCCCCCCCCCCCHHC	41.72	28102081
310	Phosphorylation	PSGARSESPRLSRKG CCCCCCCCCCHHCCC	19.30	30576142
314	Phosphorylation	RSESPRLSRKGGHER CCCCCCHHCCCCCCC	32.97	28102081
324	Phosphorylation	GGHERPPSPGLRGLL CCCCCCCCCCCCHHC	33.99	30266825
332	Phosphorylation	PGLRGLLTDSPAATV CCCCHHCCCCHHHHH	39.20	29255136
334	Phosphorylation	LRGLLTDSPAATVLA CCHHCCCCHHHHHHH	15.94	29255136
338	Phosphorylation	LTDSPAATVLAEARR CCCCHHHHHHHHHHH	20.40	25850435
347	Phosphorylation	LAEARRATESPRLGG HHHHHHHCCCCCCCC	34.87	22210691
349	Phosphorylation	EARRATESPRLGGQL HHHHHCCCCCCCCCC	15.80	21955146
362	Phosphorylation	QLPVVAISLSEYPAS CCCEEEEECCCCCCC	18.99	21955146
364	Phosphorylation	PVVAISLSEYPASGA CEEEEECCCCCCCCC	28.44	29255136
366	Phosphorylation	VAISLSEYPASGALS EEEECCCCCCCCCCC	10.75	29255136
369	Phosphorylation	SLSEYPASGALSQPT ECCCCCCCCCCCCCC	21.79	29255136
373	Phosphorylation	YPASGALSQPTSIPG CCCCCCCCCCCCCCC	33.31	29255136
376	Phosphorylation	SGALSQPTSIPGSPK CCCCCCCCCCCCCCC	31.48	29255136
377	Phosphorylation	GALSQPTSIPGSPKF CCCCCCCCCCCCCCC	33.21	29255136
381	Phosphorylation	QPTSIPGSPKFQPPV CCCCCCCCCCCCCCC	21.40	29255136
397	Phosphorylation	APRNKIGTLQDRPPS CCCCCCCCCCCCCCC	25.39	29255136
401	Methylation	KIGTLQDRPPSPFRE CCCCCCCCCCCCCCC	31.87	115368277
404	Phosphorylation	TLQDRPPSPFREPPG CCCCCCCCCCCCCCC	39.08	30266825
412	Phosphorylation	PFREPPGSERVLTTS CCCCCCCCCCEEECC	28.18	29255136
417	Phosphorylation	PGSERVLTTSPSRQL CCCCCEEECCCCCHH	23.52	30266825
418	Phosphorylation	GSERVLTTSPSRQLV CCCCEEECCCCCHHC	34.18	30266825
419	Phosphorylation	SERVLTTSPSRQLVG CCCEEECCCCCHHCC	18.68	30266825
421	Phosphorylation	RVLTTSPSRQLVGRT CEEECCCCCHHCCCC	32.21	26846344
428	Phosphorylation	SRQLVGRTFSDGLAT CCHHCCCCCCCCCCC	22.89	26657352
430	Phosphorylation	QLVGRTFSDGLATRT HHCCCCCCCCCCCCC	30.10	25463755
435	Phosphorylation	TFSDGLATRTLQPPE CCCCCCCCCCCCCCC	29.27	23403867
437	Phosphorylation	SDGLATRTLQPPESP CCCCCCCCCCCCCCC	25.95	26657352
443	Phosphorylation	RTLQPPESPRLGRRG CCCCCCCCCCCCCCC	22.54	29255136
453	Phosphorylation	LGRRGLDSMRELPPL CCCCCCHHHHHCCCC	25.45	23403867
461	Phosphorylation	MRELPPLSPSLSRRA HHHCCCCCHHHCCHH	20.44	30266825
463	Phosphorylation	ELPPLSPSLSRRALS HCCCCCHHHCCHHCC	35.28	30266825
465	Phosphorylation	PPLSPSLSRRALSPL CCCCHHHCCHHCCCC	24.86	23927012
470	Phosphorylation	SLSRRALSPLPTRTT HHCCHHCCCCCCCCC	24.33	19664994
474	Phosphorylation	RALSPLPTRTTPDPK HHCCCCCCCCCCCHH	48.62	30266825
476	Phosphorylation	LSPLPTRTTPDPKLN CCCCCCCCCCCHHHC	45.20	22199227
477	Phosphorylation	SPLPTRTTPDPKLNR CCCCCCCCCCHHHCH	23.54	25159151
489	Phosphorylation	LNREVAESPRPRRWA HCHHHHCCCCCCCCH	19.24	30266825
501	Phosphorylation	RWAAHGASPEDFSLT CCHHCCCCHHHHCEE	33.15	30266825
506	Phosphorylation	GASPEDFSLTLGARG CCCHHHHCEEECCCC	32.53	23403867
512	Methylation	FSLTLGARGRRTRSP HCEEECCCCCCCCCC	37.03	58858881
516	Phosphorylation	LGARGRRTRSPSPTL ECCCCCCCCCCCCCC	33.85	23927012
518	Phosphorylation	ARGRRTRSPSPTLGE CCCCCCCCCCCCCCC	29.17	29255136
520	Phosphorylation	GRRTRSPSPTLGESL CCCCCCCCCCCCCCC	31.59	29255136
522	Phosphorylation	RTRSPSPTLGESLAP CCCCCCCCCCCCCCC	52.30	29255136
526	Phosphorylation	PSPTLGESLAPHKGS CCCCCCCCCCCCCCC	28.21	22167270
533	Phosphorylation	SLAPHKGSFSGRLSP CCCCCCCCCCCCCCC	22.50	23927012
535	Phosphorylation	APHKGSFSGRLSPAY CCCCCCCCCCCCCCC	25.38	23927012
539	Phosphorylation	GSFSGRLSPAYSLGS CCCCCCCCCCCCCCC	13.21	30278072
542	Phosphorylation	SGRLSPAYSLGSLTG CCCCCCCCCCCCCCC	14.07	30278072
543	Phosphorylation	GRLSPAYSLGSLTGA CCCCCCCCCCCCCCC	28.49	30278072
546	Phosphorylation	SPAYSLGSLTGASPC CCCCCCCCCCCCCCC	28.22	30278072
548	Phosphorylation	AYSLGSLTGASPCQS CCCCCCCCCCCCCCC	32.19	23927012
551	Phosphorylation	LGSLTGASPCQSPCV CCCCCCCCCCCCHHH	27.79	23927012
555	Phosphorylation	TGASPCQSPCVQRKL CCCCCCCCHHHHCCC	27.30	25159151
563	Phosphorylation	PCVQRKLSSGDLRVP HHHHCCCCCCCCCCC	35.00	29255136
564	Phosphorylation	CVQRKLSSGDLRVPV HHHCCCCCCCCCCCC	46.92	30266825
572	Phosphorylation	GDLRVPVTRERKNSI CCCCCCCCCCCCCCC	22.27	23403867
578	Phosphorylation	VTRERKNSITEISDN CCCCCCCCCEECCCC	33.64	29255136
580	Phosphorylation	RERKNSITEISDNED CCCCCCCEECCCCHH	27.38	29255136
583	Phosphorylation	KNSITEISDNEDDLL CCCCEECCCCHHHHH	28.31	29255136
592	Phosphorylation	NEDDLLEYHRRQRQE CHHHHHHHHHHHHHH	10.70	23663014
624	Phosphorylation	ILNLCAEYSRADGGP HHHHHHHHHHHCCCC	5.73	27642862
638	Phosphorylation	PEAGELPSIGEATAA CCCCCCCCHHHHHHH	56.71	28857561
643	Phosphorylation	LPSIGEATAALALAG CCCHHHHHHHHHHCC	14.25	29255136
654	Phosphorylation	ALAGRRPSRGLAGAS HHCCCCCCCCCCCCC	36.85	23927012
661	Phosphorylation	SRGLAGASGRSSEEP CCCCCCCCCCCCCCC	33.55	23403867
664	Phosphorylation	LAGASGRSSEEPGVA CCCCCCCCCCCCCHH	45.70	29507054
665	Phosphorylation	AGASGRSSEEPGVAT CCCCCCCCCCCCHHH	44.62	25850435
672	Phosphorylation	SEEPGVATQRLWESM CCCCCHHHHHHHHHH	16.30	28102081
678	Phosphorylation	ATQRLWESMERSDEE HHHHHHHHHHHCCHH	17.86	28355574
682	Phosphorylation	LWESMERSDEENLKE HHHHHHHCCHHHHHH	35.75	23927012
692	Phosphorylation	ENLKEECSSTESTQQ HHHHHHHCCCHHHHH	43.50	25159151
693	Phosphorylation	NLKEECSSTESTQQE HHHHHHCCCHHHHHH	48.10	23927012
694	Phosphorylation	LKEECSSTESTQQEH HHHHHCCCHHHHHHH	20.05	23663014
696	Phosphorylation	EECSSTESTQQEHED HHHCCCHHHHHHHCC	31.44	23663014
697	Phosphorylation	ECSSTESTQQEHEDA HHCCCHHHHHHHCCC	28.21	23663014
706	Phosphorylation	QEHEDAPSTKLQGEV HHHCCCCCCHHHCEE	39.64	25072903
707	Phosphorylation	EHEDAPSTKLQGEVL HHCCCCCCHHHCEEE	34.41	25072903
731	Malonylation	LGHVEQLKVRVKELE HHHHHHHHHHHHHHH	27.91	26320211
873	Malonylation	SERLARDKNASLQLL HHHHHHHCCHHHHHH	49.19	26320211
888	Phosphorylation	QKEKEKLTVLERRYH HHHHHHHHHHHHHHH	33.83	27251275
894	Phosphorylation	LTVLERRYHSLTGGR HHHHHHHHHHHHCCC	11.28	29449344
896	Phosphorylation	VLERRYHSLTGGRPF HHHHHHHHHHCCCCC	20.77	23312004
898	Phosphorylation	ERRYHSLTGGRPFPK HHHHHHHHCCCCCCC	40.37	29449344
906	Phosphorylation	GGRPFPKTTSTLKEM CCCCCCCCHHHHHHH	26.64	25332170
908	Phosphorylation	RPFPKTTSTLKEMEK CCCCCCHHHHHHHHH	36.65	25332170
923 (in isoform 2)	Phosphorylation	-	4.18	29507054
923 (in isoform 3)	Phosphorylation	-	4.18	29507054
924 (in isoform 2)	Phosphorylation	-	34.31	30153514
924 (in isoform 3)	Phosphorylation	-	34.31	30153514
961	Phosphorylation	ASRQLQVYRSKMDGE HHHHHHHHHHCCCCC	9.01	-
963	Phosphorylation	RQLQVYRSKMDGEAT HHHHHHHHCCCCCCC	18.04	23403867
970	Phosphorylation	SKMDGEATSPLPRTR HCCCCCCCCCCCCCC	26.95	29255136
971	Phosphorylation	KMDGEATSPLPRTRS CCCCCCCCCCCCCCC	31.33	29255136
976	Phosphorylation	ATSPLPRTRSGPLPS CCCCCCCCCCCCCCC	27.52	28857561
978	Phosphorylation	SPLPRTRSGPLPSSS CCCCCCCCCCCCCCC	44.12	26657352
983	Phosphorylation	TRSGPLPSSSGSSSS CCCCCCCCCCCCCCC	44.83	23186163
984	Phosphorylation	RSGPLPSSSGSSSSS CCCCCCCCCCCCCCC	36.46	23186163
985	Phosphorylation	SGPLPSSSGSSSSSS CCCCCCCCCCCCCCC	47.21	28857561
987	Phosphorylation	PLPSSSGSSSSSSQL CCCCCCCCCCCCCCE	29.06	22199227
988	Phosphorylation	LPSSSGSSSSSSQLS CCCCCCCCCCCCCEE	37.45	22199227
989	Phosphorylation	PSSSGSSSSSSQLSV CCCCCCCCCCCCEEE	35.62	22199227
990	Phosphorylation	SSSGSSSSSSQLSVA CCCCCCCCCCCEEEE	35.64	22199227
991	Phosphorylation	SSGSSSSSSQLSVAT CCCCCCCCCCEEEEE	24.85	22199227
992	Phosphorylation	SGSSSSSSQLSVATL CCCCCCCCCEEEEEC	36.77	28985074
995	Phosphorylation	SSSSSQLSVATLGRS CCCCCCEEEEECCCC	11.32	30576142
998	Phosphorylation	SSQLSVATLGRSPSP CCCEEEEECCCCCCC	27.82	22199227
1002	Phosphorylation	SVATLGRSPSPKSAL EEEECCCCCCCHHHC	28.12	27422710
1004	Phosphorylation	ATLGRSPSPKSALLT EECCCCCCCHHHCCC	46.32	30576142
1007	Phosphorylation	GRSPSPKSALLTQNG CCCCCCHHHCCCCCC	27.77	23403867
1011	Phosphorylation	SPKSALLTQNGTGSL CCHHHCCCCCCCCCC	22.34	26657352
1015	Phosphorylation	ALLTQNGTGSLPRNL HCCCCCCCCCCCHHH	31.02	30266825
1017	Phosphorylation	LTQNGTGSLPRNLAA CCCCCCCCCCHHHHH	34.73	30266825
1025	Phosphorylation	LPRNLAATLQDIETK CCHHHHHHHHHHHHH	21.24	29514088
1032	Ubiquitination	TLQDIETKRQLALQQ HHHHHHHHHHHHHHH	25.92	-
1040	Ubiquitination	RQLALQQKGQQVIEE HHHHHHHHHHHHHHH	45.81	-
1056	Ubiquitination	RRRLAELKQKAAAEA HHHHHHHHHHHHHHH	41.06	-
1109	Phosphorylation	GEEGEHAYDTLSLES CCCCCCCCCCEECCC	16.03	-
1117	Phosphorylation	DTLSLESSDSMETSI CCEECCCCCCCCEEE	25.08	21601212
1156	Acetylation	EEMEKMLKEAHAEKN HHHHHHHHHHHHHHH	49.73	7674217
1162	Acetylation	LKEAHAEKNRLMESR HHHHHHHHHHHHHHH	48.42	7674229
1223	Phosphorylation	FSQARPLTRYLPIRK HHHHCCCCCCCCCCH	21.68	23403867
1225	Phosphorylation	QARPLTRYLPIRKED HHCCCCCCCCCCHHH	16.17	27642862
1262	Phosphorylation	SSKVCRGYLVKMGGK CCCCHHHEHHHCCCE	6.75	-
1265	Acetylation	VCRGYLVKMGGKIKS CHHHEHHHCCCEECC	29.27	7824139
1265	Ubiquitination	VCRGYLVKMGGKIKS CHHHEHHHCCCEECC	29.27	-
1269	Ubiquitination	YLVKMGGKIKSWKKR EHHHCCCEECCCCHH	41.03	-
1289	Phosphorylation	RLKRTLSYYVDKHET HHHHHHHHHHCCCCC	15.60	27067055
1290	Phosphorylation	LKRTLSYYVDKHETK HHHHHHHHHCCCCCC	9.97	27067055
1296	Phosphorylation	YYVDKHETKLKGVIY HHHCCCCCCCEEEEE	41.20	27067055
1348	Phosphorylation	VKTHDRLYYMVAPSA EEECCCEEEEECCCH	7.15	22817900
1349	Phosphorylation	KTHDRLYYMVAPSAE EECCCEEEEECCCHH	6.95	25332170

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of PHLB1_HUMAN !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of PHLB1_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of PHLB1_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
Oops, there are no PPI records of PHLB1_HUMAN !!

Drug and Disease Associations

Kegg Disease
There are no disease associations of PTM sites.
OMIM Disease
There are no disease associations of PTM sites.
Kegg Drug
There are no disease associations of PTM sites.
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of PHLB1_HUMAN

Related Literatures of Post-Translational Modification

Phosphorylation
Reference	PubMed
"A quantitative atlas of mitotic phosphorylation."; Dephoure N., Zhou C., Villen J., Beausoleil S.A., Bakalarski C.E.,Elledge S.J., Gygi S.P.; Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-220; SER-223; SER-430;SER-443; SER-501; SER-518; SER-520; SER-539; SER-551; SER-555 ANDSER-583, AND MASS SPECTROMETRY.	18669648 [Abstract]
"Combining protein-based IMAC, peptide-based IMAC, and MudPIT forefficient phosphoproteomic analysis."; Cantin G.T., Yi W., Lu B., Park S.K., Xu T., Lee J.-D.,Yates J.R. III; J. Proteome Res. 7:1346-1351(2008). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-501; THR-516 ANDSER-520, AND MASS SPECTROMETRY.	18220336 [Abstract]
"Global, in vivo, and site-specific phosphorylation dynamics insignaling networks."; Olsen J.V., Blagoev B., Gnad F., Macek B., Kumar C., Mortensen P.,Mann M.; Cell 127:635-648(2006). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-324 AND SER-583, ANDMASS SPECTROMETRY.	17081983 [Abstract]