PGBD2_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: PGBD2_HUMAN
• UniProt AC: Q6P3X8
• Protein Name: PiggyBac transposable element-derived protein 2
• Gene Name: PGBD2
• Organism: Homo sapiens (Human).
• Sequence Length: 592
• Protein Sequence: MASTSRDVIAGRGIHSKVKSAKLLEVLNAMEEEESNNNREEIFIAPPDNAAGEFTDEDSGDEDSQRGAHLPGSVLHASVLCEDSGTGEDNDDLELQPAKKRQKAVVKPQRIWTKRDIRPDFGSWTASDPHIEDLKSQELSPVGLFELFFDEGTINFIVNETNRYAWQKNVNLSLTAQELKCVLGILILSGYISYPRRRMFWETSPDSHHHLVADAIRRDRFELIFSYLHFADNNELDASDRFAKVRPLIIRMNCNFQKHAPLEEFYSFGESMCEYFGHRGSKQLHRGKPVRLGYKIWCGTTSRGYLVWFEPSQGTLFTKPDRSLDLGGSMVIKFVDALQERGFLPYHIFFDKVFTSVKLMSILRKKGVKATGTVREYRTERCPLKDPKELKKMKRGSFDYKVDESEEIIVCRWHDSSVVNICSNAVGIEPVRLTSRHSGAAKTRTQVHQPSLVKLYQEKVGGVGRMDQNIAKYKVKIRGMKWYSSFIGYVIDAALNNAWQLHRICCQDAQVDLLAFRRYIACVYLESNADTTSQGRRSRRLETESRFDMIGHWIIHQDKRTRCALCHSQTNTRCEKCQKGVHAKCFREYHIR

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
55	Phosphorylation	DNAAGEFTDEDSGDE CCCCCCCCCCCCCCC	33.89	27732954
59	Phosphorylation	GEFTDEDSGDEDSQR CCCCCCCCCCCCCCC	46.20	27732954
64	Phosphorylation	EDSGDEDSQRGAHLP CCCCCCCCCCCCCCC	21.52	27732954
73	Phosphorylation	RGAHLPGSVLHASVL CCCCCCCCCEEEEEE	21.40	27732954
78	Phosphorylation	PGSVLHASVLCEDSG CCCCEEEEEEECCCC	12.60	27732954
84	Phosphorylation	ASVLCEDSGTGEDND EEEEECCCCCCCCCC	18.89	30624053
86	Phosphorylation	VLCEDSGTGEDNDDL EEECCCCCCCCCCCC	41.15	30624053
412	Methylation	SEEIIVCRWHDSSVV CCEEEEEEECCCCHH	23.91	24396613
445	Phosphorylation	SGAAKTRTQVHQPSL CCCCCCCCCCCCHHH	39.93	29523821
451	Phosphorylation	RTQVHQPSLVKLYQE CCCCCCHHHHHHHHH	38.94	29523821
459	Ubiquitination	LVKLYQEKVGGVGRM HHHHHHHHHCCCCCC	30.56	-
561	Phosphorylation	IIHQDKRTRCALCHS HCCCCCCCCEEEECC	35.52	29978859
568	Phosphorylation	TRCALCHSQTNTRCE CCEEEECCCCCCCHH	37.39	29978859

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of PGBD2_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of PGBD2_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of PGBD2_HUMAN !!

Protein-Protein Interaction

Oops, there are no PPI records of PGBD2_HUMAN !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.