PGA2_SCHPO - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: PGA2_SCHPO
• UniProt AC: Q9P6S6
• Protein Name: PGA2-homolog C27.01c
• Gene Name: SPBC27.01c
• Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
• Sequence Length: 132
• Subcellular Localization: Endoplasmic reticulum membrane ; Single-pass membrane protein . Nucleus membrane; Single-pass membrane protein.
• Protein Description: Involved processing and trafficking glycosylated proteins..
• Protein Sequence: MGFDVAGYLQSYSLKDWIRIIVYVGGYMLIRPYLMKLGAKIQEREHRKSLLEGEVDGTLDPEMTHGTKPKEHGEFDTDDEEEEENPDAEFRWGYSARRRIRKQREEYFKNQDKSPLDAYADDDEDIEEHLED

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
77	Phosphorylation	KEHGEFDTDDEEEEE CCCCCCCCCCCHHHH	51.15	28889911
114	Phosphorylation	YFKNQDKSPLDAYAD HHHCCCCCCCHHCCC	38.70	28889911
119	Phosphorylation	DKSPLDAYADDDEDI CCCCCHHCCCCHHHH	15.38	21712547

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of PGA2_SCHPO !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of PGA2_SCHPO !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of PGA2_SCHPO !!

Protein-Protein Interaction

Oops, there are no PPI records of PGA2_SCHPO !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.

Related Literatures of Post-Translational Modification

Phosphorylation

"Phosphoproteome analysis of fission yeast.";
Wilson-Grady J.T., Villen J., Gygi S.P.;
J. Proteome Res. 7:1088-1097(2008).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-77, AND MASSSPECTROMETRY.
PubMed: 18257517