PFL5_SCHPO - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: PFL5_SCHPO
• UniProt AC: Q9URU4
• Protein Name: Putative cell agglutination protein pfl5 {ECO:0000305}
• Gene Name: pfl5 {ECO:0000303|PubMed:23236291}
• Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
• Sequence Length: 1283
• Subcellular Localization: Cell surface .
• Protein Description: May be involved in agglutination during conjugation or other aspects of colony formation (By similarity). Induces flocculation when overexpressed. [PubMed: 23236291]
• Protein Sequence: MLVFTDLIFLAIFAHIGKATAKVWNRNVQGFLDLNLPNECSQYTTIYSDGPSEYTSTLPYTHSFSNASVYTTLITITNSQCTGNYSTLTISSQPLIHTNTSISKPSQTATPQNTNTTQVSLTNGTTTNSYSNTNSLPITDTINGTTELIIPTTSYNNQSHTLIYSTYTSTYLPNSTIDLSILPHSTISTLSTVSINDTSASLSKTTSPTAGTITETIVSGSVGYTSTFPASGTTSGTVEVVEPTAGTITETIVSGSVGYTSTFPANGTTSGTVEVVEPTAGTITETIVSGSVGYTSTFPANGTTSGTVEVVEPTAGTITETIVSGSVGYTSTFPANGTTSGTVEVVEPTAGTVTETIVSGSVGYTSTFPASGTTSGTVEVVEPTAGTITETIVSGSKAFTSTFPANGTTSGTVEVVEPTAGTITKTIVSGSKTFTSTFPANGTTSGTVEVVEPTAGTITETIVSGSVGYTSTFPANGTTSGTVEVVEPTAGTITETIVSGSKTFTSTFPASGTTSGTVEVVEPTAGTITETIVSGSKAFTSTFPANGTTSGTVEVVEPTAGTITETIVSGSVGYTSTFPASGTTSGTVEVVEPTAGTVTETIVSGSVGYTSTFPASGTTSGTVEVVEPTAGTVTETIVSGSVGYTSTFPASGTTSGTVEVVEPTAGTITETIVSGSKAFTSTFPANGTTSGTVEVVEPTAGTITETIVSGSKTFTSTFPANGTTSGTVEVVEPTAGTITETIVSGSVGYTSTFPASGTTSGTVEVVEPTAGTVTETVISGSVSFMSTITAHDTSSGAVIVVEPTAGTVTETIVSGSIPFTSTIPAQGTTSGTVEVVEPTAGTVTETIISGSVGYTSTFPAQGTTSGTVEVVEPTAGTVTETIISGSVGYTSTFPAQGTTSGTVEIVAPTAGTVTETIVSGSIPFTSTIPAQGTTSGTVEVVEPTAGTVTETIISGSVGYTSTFPAQGTTSGTVEIVAPTAGTVTETIVSGSIPFTSTIPAQGTTSGTVEVVEPTAGTVTETIISGSVGYTSTFPAQGTTSGTVEVVEPTAGTVTETIVSGSIPFTSTIPAQGTTSGTVEIVVPTAGTVTSTTGSGTSWFTTTVPATGTRSGSVIVVSPTAPACSSTPFAECPNLNFNFHSKNVNFPPADIRVISVTPKGNNMYDATVQFTTSSTMSKKSLSELKILGLSQTYLLYSYNSKVDNISNPGSWTSTVTVQGTSTGSYICMPHFQIQYDWCSAGVTDMSECNTWSYQKSYDYITGCNNYDNQGNSQTDASDYCWNVC

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
66	N-linked_Glycosylation	PYTHSFSNASVYTTL CCEECCCCCEEEEEE		-
84	N-linked_Glycosylation	TNSQCTGNYSTLTIS ECCCCCCCCEEEEEE		-
99	N-linked_Glycosylation	SQPLIHTNTSISKPS CCCEEECCCCCCCCC		-
115	N-linked_Glycosylation	TATPQNTNTTQVSLT CCCCCCCCCCEEEEC		-
123	N-linked_Glycosylation	TTQVSLTNGTTTNSY CCEEEECCCCCCCCC		-
143	N-linked_Glycosylation	LPITDTINGTTELII CCCEEECCCEEEEEE		-
157	N-linked_Glycosylation	IPTTSYNNQSHTLIY EECCCCCCCCEEEEE		-
174	N-linked_Glycosylation	YTSTYLPNSTIDLSI EECEECCCCEEEEEE		-
196	N-linked_Glycosylation	TLSTVSINDTSASLS EEEEEEECCCCCCCC		-
266	N-linked_Glycosylation	YTSTFPANGTTSGTV EEEEECCCCCCCEEE		-
301	N-linked_Glycosylation	YTSTFPANGTTSGTV EEEEECCCCCCCEEE		-
336	N-linked_Glycosylation	YTSTFPANGTTSGTV EEEEECCCCCCCEEE		-
406	N-linked_Glycosylation	FTSTFPANGTTSGTV EEEECCCCCCCCEEE		-
441	N-linked_Glycosylation	FTSTFPANGTTSGTV EEEEECCCCCCCEEE		-
476	N-linked_Glycosylation	YTSTFPANGTTSGTV EEEEECCCCCCCEEE		-
546	N-linked_Glycosylation	FTSTFPANGTTSGTV EEEECCCCCCCCEEE		-
686	N-linked_Glycosylation	FTSTFPANGTTSGTV EEEECCCCCCCCEEE		-
721	N-linked_Glycosylation	FTSTFPANGTTSGTV EEEECCCCCCCCEEE		-
1203	N-linked_Glycosylation	SYNSKVDNISNPGSW EECCCCCCCCCCCCE		-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of PFL5_SCHPO !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of PFL5_SCHPO !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of PFL5_SCHPO !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
PFL9_SCHPO	pfl9	genetic	23236291
PVG4_SCHPO	mbx2	genetic	23236291

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.