PF4V_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: PF4V_HUMAN
• UniProt AC: P10720
• Protein Name: Platelet factor 4 variant
• Gene Name: PF4V1
• Organism: Homo sapiens (Human).
• Sequence Length: 104
• Subcellular Localization: Secreted.
• Protein Description: Inhibitor of angiogenesis. Inhibitor of endothelial cell chemotaxis (in vitro)..
• Protein Sequence: MSSAARSRLTRATRQEMLFLALLLLPVVVAFARAEAEEDGDLQCLCVKTTSQVRPRHITSLEVIKAGPHCPTAQLIATLKNGRKICLDLQALLYKKIIKEHLES

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
2	Phosphorylation	------MSSAARSRL ------CCHHHHHHH	28.78	-
7	Phosphorylation	-MSSAARSRLTRATR -CCHHHHHHHHHHHH	27.24	-
59	Phosphorylation	QVRPRHITSLEVIKA CCCCCEECEEEEECC	22.57	28270605
60	Phosphorylation	VRPRHITSLEVIKAG CCCCEECEEEEECCC	23.17	28270605
94	Phosphorylation	LDLQALLYKKIIKEH HHHHHHHHHHHHHHH	15.87	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of PF4V_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of PF4V_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of PF4V_HUMAN !!

Protein-Protein Interaction

Oops, there are no PPI records of PF4V_HUMAN !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.