dbPTM

PF21B_HUMAN - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	PF21B_HUMAN
UniProt AC	Q96EK2
Protein Name	PHD finger protein 21B
Gene Name	PHF21B
Organism	Homo sapiens (Human).
Sequence Length	531
Subcellular Localization
Protein Description
Protein Sequence	MELQSRPEALAVELARHQNGDLKKQLHERQPRIAALSDKQALGTITAVPVTGPQVSSLQRLAGQGAAVLPQVRPKTLIPDSLPVAPGRDRPPKQPPTFQKATVVSVKNPSPALPTANNTVSHVPAPGSQPQALAEPAALASPLSSAGVAYAIISTSPSNAAAMAPSTAVSVVSDSIKVQPLLISADNKPPPRLLSSPHPATHHCPLHPSSLPLTPPSPSLSPSPLHGIFQVIIIQPQVQTQPESTAESRPPTEEPSQGAQATKKKKEDRPPTQENPEKIAFMVALGLVTTEHLEEIQSKRQERKRRSTANPAYSGLLETERKRLASNYLNNPLFLTARANEDPCWKNEITHDEHCAACKRGANLQPCGTCPGAYHLSCLEPPLKTAPKGVWVCPRCQQKALKKDEGVPWTGMLAIVHSYVTHKTVKEEEKQKLLQRGSELQNEHQQLEERDRRLASAVQKCLELKTSLLARQRGTQSSLDRLRALLRLIQGEQLLQVTMTTTSPAPLLAGPWTKPSVAATHPTVQHPQGHN

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
252	Phosphorylation	TAESRPPTEEPSQGA CCCCCCCCCCCCHHH	56.51	-
272	Phosphorylation	KKEDRPPTQENPEKI CCCCCCCCCCCHHHH	51.72	24719451
410	Phosphorylation	KDEGVPWTGMLAIVH CCCCCCCCHHHHHHH	13.47	29116813
418	Phosphorylation	GMLAIVHSYVTHKTV HHHHHHHHHHCCCCC	15.48	29116813
419	Phosphorylation	MLAIVHSYVTHKTVK HHHHHHHHHCCCCCC	8.42	29116813
421	Phosphorylation	AIVHSYVTHKTVKEE HHHHHHHCCCCCCHH	14.93	29116813
475	Phosphorylation	LLARQRGTQSSLDRL HHHHHHCCHHHHHHH	27.71	27174698
477	Phosphorylation	ARQRGTQSSLDRLRA HHHHCCHHHHHHHHH	32.48	27174698
478	Phosphorylation	RQRGTQSSLDRLRAL HHHCCHHHHHHHHHH	25.19	22210691
498	Phosphorylation	GEQLLQVTMTTTSPA HHHEEEEEEECCCCC	8.88	22210691

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of PF21B_HUMAN !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of PF21B_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of PF21B_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
Oops, there are no PPI records of PF21B_HUMAN !!

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of PF21B_HUMAN

Related Literatures of Post-Translational Modification