dbPTM

PESC_SCHPO - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	PESC_SCHPO
UniProt AC	O60164
Protein Name	Pescadillo homolog {ECO:0000255\|HAMAP-Rule:MF_03028}
Gene Name	ppp1
Organism	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
Sequence Length	607
Subcellular Localization	Nucleus, nucleoplasm . Nucleus, nucleolus .
Protein Description	Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome..
Protein Sequence	MARVKQKGKAGAARIYITRNQALKKLQLTLADFRRICILKGVYPREPKNKKKANKGSTAPVTFYYTKDIQYLLHEPIVQKFREYKVFARKLSKALGKGELETAKRLEARKPTYSLDHIIKERYPTFHDALKDIDDALSMLFLFSTMPVTDKIGAATVANCERLCAEFQHYVIRSNSLRKAFLSIKGIYYQAEIFGEQITWIVPYKFAQSVPTDVDFRIMHTFLEFYQALMGFVNFKLYNTLGLRYPPKIDVAKSESAAGLAAYELEESSSLPAIVHGNNKNARKNIATLKSKIRDIVNSDANVVEQSEKTTEDADEEPETEENLDEFKPADGADNEDSKSLVSHISSSNTSLFSNFTFFLSREVPRFSLEFVIRAFGGKVGWDPILGSGSPFSESDPVITHHICDRPHISQKYEGRIYIQPQWVYDSINKGILERTDLYACGATLPPHLSPFVKVGENDYDPEAELSAEENDDVSEALDDNISGEAVPISKKNDEPENVEQIDDAEEEDLEHQRELEAEAGGVAYSEYVKQNSKSAKKTKKRQRDTLTAEEKEEKEAKELSKMMMSNKQRKLYSKLKNENSKNENYNNALRNRKRDIEKRKKLKVEN

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
320	Phosphorylation	DADEEPETEENLDEF CCCCCCCCHHCHHHC	60.35	29996109
467	Phosphorylation	YDPEAELSAEENDDV CCHHHHHCHHHCCCH	25.74	28889911
475	Phosphorylation	AEENDDVSEALDDNI HHHCCCHHHHHCCCC	24.93	25720772
483	Phosphorylation	EALDDNISGEAVPIS HHHCCCCCCCCCCCC	36.51	29996109

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of PESC_SCHPO !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of PESC_SCHPO !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of PESC_SCHPO !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
Oops, there are no PPI records of PESC_SCHPO !!

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of PESC_SCHPO

Related Literatures of Post-Translational Modification