PEP7_SCHPO - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: PEP7_SCHPO
• UniProt AC: O13786
• Protein Name: Vacuolar segregation protein pep7
• Gene Name: pep7
• Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
• Sequence Length: 536
• Protein Description: Required for vacuole segregation and vacuole protein sorting. Possibly part of a complex which tethers the vacuole membrane to microtubules, either directly or via kinesin or dynein-like motor proteins. Probably functions in several interorganelle traffic pathways (By similarity)..
• Protein Sequence: MQNGKRRIGVRISSNLSNHSGTNLSTSAQSDSSNIVKATECPICGLELPNLSALNDHLDVTHFNDNEKIHKRQDSINSWLTRTLNGASALQMKAAQRLWRMEPYEQNGDSSGAVGLEATKLTDSLVVKNHWQPEVPDMVCHDPMCDKLLNFINGHIHCRKCGYIFCNFHSMYQIKLSIHATYDSENGFWCRVCRECYEGRPGYNDSNGLIRSRFQTFETFRKPLADKRRIEFLRLSKRMKKLEELWTSENVSMLDALLLNKAKRLEQSIVHWQDDSVVQICPECNNSFTLTRRRRHCRLCGRVICRFCVLEISLPQHPQPLLICMSCNQNYFRNVLYQTERSKSLGYIRHIEHLQVFRQAMVNYYRLYEDSLSELLSGEIITEATLKIVKDRRKKFLELCVKYDGTMKKIANHPSSNDAEEQFKQNVVNEAKRYLQETILRLQAIPYHLQVGQAWTSESERELEKKKEQVEKKQEELMQTRIVLEEQVFLVENMIEDAKAKRKFSEVETLLSSLAPLHEEIHSITEKIHDLDLFDI

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
13	Phosphorylation	RRIGVRISSNLSNHS EEEEEEECCCCCCCC	11.56	25720772
17	Phosphorylation	VRISSNLSNHSGTNL EEECCCCCCCCCCCC	36.43	25720772
20	Phosphorylation	SSNLSNHSGTNLSTS CCCCCCCCCCCCCCC	52.11	25720772
22	Phosphorylation	NLSNHSGTNLSTSAQ CCCCCCCCCCCCCCC	35.68	25720772
26	Phosphorylation	HSGTNLSTSAQSDSS CCCCCCCCCCCCCCC	31.11	25720772
27	Phosphorylation	SGTNLSTSAQSDSSN CCCCCCCCCCCCCCC	22.42	25720772
30	Phosphorylation	NLSTSAQSDSSNIVK CCCCCCCCCCCCCCC	38.89	25720772
32	Phosphorylation	STSAQSDSSNIVKAT CCCCCCCCCCCCCHH	30.45	25720772
33	Phosphorylation	TSAQSDSSNIVKATE CCCCCCCCCCCCHHC	35.25	25720772
75	Phosphorylation	KIHKRQDSINSWLTR HHHCCHHHHHHHHHH	18.48	25720772
78	Phosphorylation	KRQDSINSWLTRTLN CCHHHHHHHHHHHHC	23.07	21712547

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of PEP7_SCHPO !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of PEP7_SCHPO !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of PEP7_SCHPO !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
VPS45_SCHPO	vps45	physical	26771498

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.