PDXK_ARATH - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: PDXK_ARATH
• UniProt AC: Q8W1X2
• Protein Name: Pyridoxal kinase
• Gene Name: PK
• Organism: Arabidopsis thaliana (Mouse-ear cress).
• Sequence Length: 309
• Protein Description: Catalyzes the transfer of a phosphate group from ATP to the 5-hydroxylmethyl group of pyridoxal to form the biologically active pyridoxal phosphate..
• Protein Sequence: MTTPPVLSLALPSDTGRVLSIQSHTVQGYVGNKSAVFPLQLLGYDVDPINSVQFSNHTGYPTFKGQVLNGQQLCDLIEGLEANDLLFYTHVLTGYIGSVSFLDTILEVINKLRSVNPNLTYVCDPVMGDEGKLYVPEELVHVYREKVVPLASMLTPNQFEAEKLTGLRINSEEDGREACAILHAAGPSKVVITSITIGGILLLIGSHQKEKGLKPEQFKILIHKIPAYFTGTGDLMTALLLGWSNKYPDNLDKAAELAVSTLQALLRRTLDDYKRAGYDPTSSSLEIRLIQSQEDIRNPKVELKAERYS

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
2	Acetylation	------MTTPPVLSL ------CCCCCEEEE	48.27	22223895
281	Phosphorylation	KRAGYDPTSSSLEIR HHCCCCCCCCHHHEE	38.04	19880383
282	Phosphorylation	RAGYDPTSSSLEIRL HCCCCCCCCHHHEEE	24.26	19880383
283	Phosphorylation	AGYDPTSSSLEIRLI CCCCCCCCHHHEEEC	41.23	19880383

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of PDXK_ARATH !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of PDXK_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of PDXK_ARATH !!

Protein-Protein Interaction

Oops, there are no PPI records of PDXK_ARATH !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.