| UniProt ID | PDLI3_HUMAN | |
|---|---|---|
| UniProt AC | Q53GG5 | |
| Protein Name | PDZ and LIM domain protein 3 | |
| Gene Name | PDLIM3 | |
| Organism | Homo sapiens (Human). | |
| Sequence Length | 364 | |
| Subcellular Localization | Cytoplasm, myofibril, sarcomere, Z line . Localizes to myofiber Z-lines. | |
| Protein Description | May play a role in the organization of actin filament arrays within muscle cells.. | |
| Protein Sequence | MPQTVILPGPAPWGFRLSGGIDFNQPLVITRITPGSKAAAANLCPGDVILAIDGFGTESMTHADAQDRIKAAAHQLCLKIDRGETHLWSPQVSEDGKAHPFKINLESEPQDGNYFEHKHNIRPKPFVIPGRSSGCSTPSGIDCGSGRSTPSSVSTVSTICPGDLKVAAKLAPNIPLEMELPGVKIVHAQFNTPMQLYSDDNIMETLQGQVSTALGETPLMSEPTASVPPESDVYRMLHDNRNEPTQPRQSGSFRVLQGMVDDGSDDRPAGTRSVRAPVTKVHGGSGGAQRMPLCDKCGSGIVGAVVKARDKYRHPECFVCADCNLNLKQKGYFFIEGELYCETHARARTKPPEGYDTVTLYPKA | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 18 | Phosphorylation | APWGFRLSGGIDFNQ CCCCEEECCCCCCCC | 30.62 | 26657352 | |
| 57 | Phosphorylation | LAIDGFGTESMTHAD EEECCCCCCCCCCCC | 23.72 | 19413330 | |
| 85 | Phosphorylation | LKIDRGETHLWSPQV EEECCCCCEEECCEE | 25.70 | 23312004 | |
| 89 | Phosphorylation | RGETHLWSPQVSEDG CCCCEEECCEECCCC | 16.30 | 26657352 | |
| 93 | Phosphorylation | HLWSPQVSEDGKAHP EEECCEECCCCCCCC | 25.40 | 26657352 | |
| 132 | Phosphorylation | PFVIPGRSSGCSTPS CEECCCCCCCCCCCC | 36.68 | 22210691 | |
| 133 | Phosphorylation | FVIPGRSSGCSTPSG EECCCCCCCCCCCCC | 42.32 | 19764811 | |
| 136 | Phosphorylation | PGRSSGCSTPSGIDC CCCCCCCCCCCCCCC | 47.05 | 19764811 | |
| 137 | Phosphorylation | GRSSGCSTPSGIDCG CCCCCCCCCCCCCCC | 26.08 | 19764811 | |
| 142 (in isoform 3) | Phosphorylation | - | 33.96 | 29523821 | |
| 142 (in isoform 2) | Phosphorylation | - | 33.96 | 29523821 | |
| 143 (in isoform 3) | Phosphorylation | - | 4.40 | 29523821 | |
| 143 (in isoform 2) | Phosphorylation | - | 4.40 | 29523821 | |
| 145 (in isoform 3) | Phosphorylation | - | 37.05 | 29523821 | |
| 145 (in isoform 2) | Phosphorylation | - | 37.05 | 29523821 | |
| 145 | Phosphorylation | PSGIDCGSGRSTPSS CCCCCCCCCCCCCCC | 37.05 | 19764811 | |
| 148 | Phosphorylation | IDCGSGRSTPSSVST CCCCCCCCCCCCCCC | 48.47 | 19764811 | |
| 149 | Phosphorylation | DCGSGRSTPSSVSTV CCCCCCCCCCCCCCC | 26.32 | 19764811 | |
| 150 (in isoform 2) | Phosphorylation | - | 26.34 | - | |
| 150 (in isoform 3) | Phosphorylation | - | 26.34 | - | |
| 151 | Phosphorylation | GSGRSTPSSVSTVST CCCCCCCCCCCCCCE | 43.38 | 19764811 | |
| 151 (in isoform 3) | Phosphorylation | - | 43.38 | 27251275 | |
| 151 (in isoform 2) | Phosphorylation | - | 43.38 | 27251275 | |
| 152 (in isoform 3) | Phosphorylation | - | 22.69 | 27251275 | |
| 152 | Phosphorylation | SGRSTPSSVSTVSTI CCCCCCCCCCCCCEE | 22.69 | 22210691 | |
| 152 (in isoform 2) | Phosphorylation | - | 22.69 | 27251275 | |
| 153 (in isoform 3) | Phosphorylation | - | 6.98 | 27251275 | |
| 153 (in isoform 2) | Phosphorylation | - | 6.98 | 27251275 | |
| 154 | Phosphorylation | RSTPSSVSTVSTICP CCCCCCCCCCCEECC | 25.66 | 28348404 | |
| 155 | Phosphorylation | STPSSVSTVSTICPG CCCCCCCCCCEECCC | 19.13 | 22210691 | |
| 169 (in isoform 3) | Phosphorylation | - | 35.13 | 30266825 | |
| 169 (in isoform 2) | Phosphorylation | - | 35.13 | 26657352 | |
| 170 (in isoform 2) | Phosphorylation | - | 9.09 | 26657352 | |
| 170 (in isoform 3) | Phosphorylation | - | 9.09 | 30266825 | |
| 176 (in isoform 2) | Phosphorylation | - | 9.66 | 26657352 | |
| 221 | Phosphorylation | LGETPLMSEPTASVP HCCCCCCCCCCCCCC | 48.37 | 26657352 | |
| 245 | Phosphorylation | HDNRNEPTQPRQSGS CCCCCCCCCCCCCCC | 45.05 | 29214152 | |
| 250 | Phosphorylation | EPTQPRQSGSFRVLQ CCCCCCCCCCEEEEE | 37.37 | 19764811 | |
| 252 | Phosphorylation | TQPRQSGSFRVLQGM CCCCCCCCEEEEEEE | 18.35 | 26437602 | |
| 264 | Phosphorylation | QGMVDDGSDDRPAGT EEEECCCCCCCCCCC | 43.25 | 26437602 | |
| 273 | Phosphorylation | DRPAGTRSVRAPVTK CCCCCCCEEECCEEE | 18.78 | 26437602 | |
| 285 | Phosphorylation | VTKVHGGSGGAQRMP EEEECCCCCCCCCCC | 38.35 | 26437602 | |
| 299 | Phosphorylation | PLCDKCGSGIVGAVV CCCCCCCCCHHHHHE | 34.51 | - | |
| 312 | Phosphorylation | VVKARDKYRHPECFV HEECCCCCCCCCEEE | 20.60 | - | |
| 355 | Phosphorylation | RTKPPEGYDTVTLYP CCCCCCCCCEEEEEE | 13.53 | 28674419 | |
| 357 | Phosphorylation | KPPEGYDTVTLYPKA CCCCCCCEEEEEECC | 13.60 | - | |
| 361 | Phosphorylation | GYDTVTLYPKA---- CCCEEEEEECC---- | 8.04 | 20007894 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of PDLI3_HUMAN !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of PDLI3_HUMAN !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of PDLI3_HUMAN !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
Oops, there are no PPI records of PDLI3_HUMAN !! | ||||
| Kegg Disease | ||||||
|---|---|---|---|---|---|---|
| There are no disease associations of PTM sites. | ||||||
| OMIM Disease | ||||||
| There are no disease associations of PTM sites. | ||||||
| Kegg Drug | ||||||
| There are no disease associations of PTM sites. | ||||||
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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