PDIP2_MOUSE - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: PDIP2_MOUSE
• UniProt AC: Q91VA6
• Protein Name: Polymerase delta-interacting protein 2
• Gene Name: Poldip2
• Organism: Mus musculus (Mouse).
• Sequence Length: 368
• Subcellular Localization: Nucleus .
• Protein Sequence: MAGCVARRALAVGSRWWSRSLATTRGSRPLCAVGGAGGLPPVATATTRRHLSSRNRAEGKVLETVGVFEVPKQNGKYETGQLFLHSVFGYRGVVLFPWQARLYDRDVASATPEKAENPAGHGSKEVKGKTHTYYQVLIDARDCPHISQRSQTEAVTFLANHDDSRALYAIPGLDYVSHEDILPYTSTDQVPIQHELFERFLLYDQTKAPPFVARETLRAWQEKNHPWLELSDVHRETTENIRVTVIPFYMGMREAQNSHVYWWRYCIRLENLDSDVVQLRERHWRIFSLSGTLETVRGRGVVGREPVLSKEQPAFQYSSHVSLQASSGHMWGTFRFERPDGSHFDVRIPPFSLESNKDEKTPPSGLHW

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
27	Phosphorylation	SLATTRGSRPLCAVG HHHCCCCCCCEEECC	27.68	20139300
76	Acetylation	EVPKQNGKYETGQLF EECCCCCCEECCCEE	47.68	23954790
143	Glutathionylation	VLIDARDCPHISQRS EEEECCCCCCCCCCC	1.89	24333276
288	Phosphorylation	ERHWRIFSLSGTLET HHCEEEEEEECEEEE	21.18	23984901
290	Phosphorylation	HWRIFSLSGTLETVR CEEEEEEECEEEEEC	28.65	29895711
292	Phosphorylation	RIFSLSGTLETVRGR EEEEEECEEEEECCC	20.32	26824392
295	Phosphorylation	SLSGTLETVRGRGVV EEECEEEEECCCCCC	20.72	26745281

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of PDIP2_MOUSE !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of PDIP2_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of PDIP2_MOUSE !!

Protein-Protein Interaction

Oops, there are no PPI records of PDIP2_MOUSE !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.