dbPTM

PDI52_ARATH - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	PDI52_ARATH
UniProt AC	Q94F09
Protein Name	Protein disulfide-isomerase 5-2
Gene Name	PDIL5-2
Organism	Arabidopsis thaliana (Mouse-ear cress).
Sequence Length	440
Subcellular Localization	Membrane Single-pass membrane protein .
Protein Description	Acts as a protein-folding catalyst that interacts with nascent polypeptides to catalyze the formation, isomerization, and reduction or oxidation of disulfide bonds..
Protein Sequence	MRSLKLLLCWISFLTLSISISASSDDQFTLDGTVLELTDSNFDSAISTFDCIFVDFYAPWCGHCKRLNPELDAAAPILAKLKQPIVIAKLNADKYSRLARKIEIDAFPTLMLYNHGVPMEYYGPRKADLLVRYLKKFVAPDVAVLESDSTVKEFVEDAGTFFPVFIGFGLNESIISGLGRKYKKKAWFAVSKEVSEDTMVSYDFDKAPALVANHPTYNEHSVFYGPFEDGFLEEFVKQSFLPLILPINHDTLKLLKDDERKIVLTIVEDETHESLEKLYKALRAAAHANRDLVFGYVGVKQFEEFVDSFHVDKKTNLPKIVVWDGDEEYDQVTGIETITQEEDHLTQVSRFLEGYREGRTEKKKINGPSFMGFINSMIGIRSVYILVFLVAVIMMLRSLGQVEEPTGVRTATAVRERVDQATTVPEDESSEHKPSDKKED

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
160	Phosphorylation	EFVEDAGTFFPVFIG HHHHHHCCCEEEEEE	24.67	19245862
171	N-linked_Glycosylation	VFIGFGLNESIISGL EEEECCCCHHHHHCC	41.15	-
412	Phosphorylation	PTGVRTATAVRERVD CCCCCHHHHHHHHHH	25.68	19880383
429	Phosphorylation	TTVPEDESSEHKPSD CCCCCCCCCCCCCCC	54.04	27532006
430	Phosphorylation	TVPEDESSEHKPSDK CCCCCCCCCCCCCCC	41.49	27532006
435	Phosphorylation	ESSEHKPSDKKED-- CCCCCCCCCCCCC--	67.85	27532006

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of PDI52_ARATH !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of PDI52_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of PDI52_ARATH !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
Oops, there are no PPI records of PDI52_ARATH !!

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of PDI52_ARATH

Related Literatures of Post-Translational Modification