PDE6D_MOUSE - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: PDE6D_MOUSE
• UniProt AC: O55057
• Protein Name: Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta
• Gene Name: Pde6d
• Organism: Mus musculus (Mouse).
• Sequence Length: 150
• Subcellular Localization: Cytoplasm, cytosol . Cytoplasmic vesicle membrane ; Peripheral membrane protein . Cytoplasm, cytoskeleton, cilium basal body .
• Protein Description: Promotes the release of prenylated target proteins from cellular membranes. [PubMed: 22179043 Modulates the activity of prenylated or palmitoylated Ras family members by regulating their subcellular location]
• Protein Sequence: MSAKDERARDILRGFKLNWMNLRDAETGKILWQGTEDLSVPGVEHEARVPKKILKCKAVSRELNFSSAEQMEKFRLEQKVYFKGQCLEEWFFEFGFVIPNSTNTWQSLIEAAPESQMMPASVLTGNVIIETKFFDDDLLVSTSKVRLFYV

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
16	Acetylation	RDILRGFKLNWMNLR HHHHHHCCCEECCCC	43.67	22826441
79	Acetylation	EKFRLEQKVYFKGQC HHHCCEEEEEEECHH	29.53	22826441

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of PDE6D_MOUSE !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of PDE6D_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of PDE6D_MOUSE !!

Protein-Protein Interaction

Oops, there are no PPI records of PDE6D_MOUSE !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.