PCY1B_RAT - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: PCY1B_RAT
• UniProt AC: Q9QZC4
• Protein Name: Choline-phosphate cytidylyltransferase B
• Gene Name: Pcyt1b
• Organism: Rattus norvegicus (Rat).
• Sequence Length: 369
• Subcellular Localization: Endoplasmic reticulum.
• Protein Description: Controls phosphatidylcholine synthesis..
• Protein Sequence: MPVVTTDAESETGIPKSLSNEPPSETMEEIEHTCPQPRLTLTAPAPFADESSCQCQAPHEKLTIAQARLGTPVDRPVRVYADGIFDLFHSGHARALMQAKTLFPNSYLLVGVCSDDLTHKFKGFTVMNEAERYEALRHCRYVDEVIRDAPWTLTPEFLEKHKIDFVAHDDIPYSSAGSDDVYKHIKEAGMFVPTQRTEGISTSDIITRIVRDYDVYARRNLQRGYTAKELNVSFINEKKYRFQNQVDKMKEKVKNVEERSKEFVNRVEEKSHDLIQKWEEKSREFIGNFLELFGPDGAWKQMFQERSSRMLQALSPKQSPVSSPTRSRSPSRSPSPTFSWLPNKTSPPSSPKAASASISSMSEGDEDEK

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
233	Phosphorylation	TAKELNVSFINEKKY CEEECCCEEECHHHH	21.24	28432305
270	Ubiquitination	FVNRVEEKSHDLIQK HHHHHHHHCHHHHHH	39.32	-
315	Phosphorylation	SRMLQALSPKQSPVS HHHHHHHCCCCCCCC	32.82	24259510
319	Phosphorylation	QALSPKQSPVSSPTR HHHCCCCCCCCCCCC	33.14	28432305
322	Phosphorylation	SPKQSPVSSPTRSRS CCCCCCCCCCCCCCC	33.70	28432305
323	Phosphorylation	PKQSPVSSPTRSRSP CCCCCCCCCCCCCCC	30.44	28432305
325	Phosphorylation	QSPVSSPTRSRSPSR CCCCCCCCCCCCCCC	43.13	28432305
329	Phosphorylation	SSPTRSRSPSRSPSP CCCCCCCCCCCCCCC	28.59	-
331	Phosphorylation	PTRSRSPSRSPSPTF CCCCCCCCCCCCCCC	46.79	-
333	Phosphorylation	RSRSPSRSPSPTFSW CCCCCCCCCCCCCCC	33.78	28432305
335	Phosphorylation	RSPSRSPSPTFSWLP CCCCCCCCCCCCCCC	37.51	27097102
337	Phosphorylation	PSRSPSPTFSWLPNK CCCCCCCCCCCCCCC	34.34	28432305
339	Phosphorylation	RSPSPTFSWLPNKTS CCCCCCCCCCCCCCC	30.13	28432305
345	Phosphorylation	FSWLPNKTSPPSSPK CCCCCCCCCCCCCCC	53.78	28432305
346	Phosphorylation	SWLPNKTSPPSSPKA CCCCCCCCCCCCCCC	36.10	29779826
349	Phosphorylation	PNKTSPPSSPKAASA CCCCCCCCCCCCCHH	63.76	28432305
350	Phosphorylation	NKTSPPSSPKAASAS CCCCCCCCCCCCHHH	35.87	28432305
355	Phosphorylation	PSSPKAASASISSMS CCCCCCCHHHHHCCC	27.66	-
359	Phosphorylation	KAASASISSMSEGDE CCCHHHHHCCCCCCC	19.93	25403869
360	Phosphorylation	AASASISSMSEGDED CCHHHHHCCCCCCCC	25.34	25403869
362	Phosphorylation	SASISSMSEGDEDEK HHHHHCCCCCCCCCC	40.13	25403869

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of PCY1B_RAT !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of PCY1B_RAT !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of PCY1B_RAT !!

Protein-Protein Interaction

Oops, there are no PPI records of PCY1B_RAT !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.