PCS_SCHPO - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: PCS_SCHPO
• UniProt AC: Q10075
• Protein Name: Glutathione gamma-glutamylcysteinyltransferase
• Gene Name: SPAC3H1.10
• Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
• Sequence Length: 414
• Protein Description: Required for detoxification of heavy metals such as cadmium and arsenate..
• Protein Sequence: MNIVKRAVPELLRGMTNATPNIGLIKNKVVSFEAVGQLKKSFYKRQLPKQCLAFDSSLGKDVFLRALQEGRMENYFSLAQQMVTQNEPAFCGLGTLCMILNSLKVDPGRLWKGSWRWYDQYMLDCCRSLSDIEKDGVTLEEFSCLANCNGLRTITKCVKDVSFDEFRKDVISCSTIENKIMAISFCRKVLGQTGDGHFSPVGGFSESDNKILILDVARFKYPCYWVDLKLMYESMFPIDKASGQPRGYVLLEPMHIPLGVLTVGLNKYSWRNVSKHILQQAATVKNADNLAEILLSINQSSIPLIQERSNSSKSGDFEHFKECIRSTKTYHLFLKHTNTNVEYITMAFWAIFSLPMIQKALPKGVLEEIQSLLKEVEISEINTQLTALKKQLDSLTHCCKTDTGCCSSSCCKNT

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
221	Phosphorylation	LDVARFKYPCYWVDL EEEHHCCCCEEEEEH	8.88	25720772
224	Phosphorylation	ARFKYPCYWVDLKLM HHCCCCEEEEEHHHH	12.17	25720772
234	Phosphorylation	DLKLMYESMFPIDKA EHHHHHHHCCCCCCC	14.29	25720772

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of PCS_SCHPO !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of PCS_SCHPO !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of PCS_SCHPO !!

Protein-Protein Interaction

Oops, there are no PPI records of PCS_SCHPO !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.