dbPTM

PCMD2_MOUSE - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	PCMD2_MOUSE
UniProt AC	Q8BHD8
Protein Name	Protein-L-isoaspartate O-methyltransferase domain-containing protein 2
Gene Name	Pcmtd2
Organism	Mus musculus (Mouse).
Sequence Length	359
Subcellular Localization	Cytoplasm.
Protein Description
Protein Sequence	MGGAVSAGEDNDELIDNLKEAQYIRTDLVEQAFRAIDRADYYLEEFKENAYKDLAWKHGNIHLSAPCIYSEVMEALDLQPGLSFLNLGSGTGYLSSMVGLILGPFGVNHGVELHSDVTEYAKQKLDVFIRTSDSFDKFDFCEPSFVTGNCLEIAPDCCQYDRVYCGAGVQKEHEEYMKNLLKVGGILVMPLEEKLTKITRTGPSAWETKKILAVSFAPLVQPCRSESGQSRLVQLPPPAVRSLQDLARLAIRGSIKRAMRQEATRGGGLKNTPMFKRRRVRRRRMETIVFLDKEVFASRISNPSDDTSCEDAEEDRREVAERTLQETKPEPPVNFLRQRVLRLPLPDPLKYYLLYYREK

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
2	Myristoylation	------MGGAVSAGE ------CCCCCCCCC	32.54	-
6	Phosphorylation	--MGGAVSAGEDNDE --CCCCCCCCCCCHH	29.98	28066266
124	Ubiquitination	VTEYAKQKLDVFIRT HHHHHHHHCCEEEEC	46.04	-
272	Phosphorylation	RGGGLKNTPMFKRRR CCCCCCCCHHHHHHH	17.97	26824392
287	Phosphorylation	VRRRRMETIVFLDKE HHHHHHEEEEEECHH	17.07	29514104
301	Phosphorylation	EVFASRISNPSDDTS HHHHHHCCCCCCCCC	41.39	23684622
304	Phosphorylation	ASRISNPSDDTSCED HHHCCCCCCCCCCCC	52.98	23684622
307	Phosphorylation	ISNPSDDTSCEDAEE CCCCCCCCCCCCHHH	40.02	23684622
308	Phosphorylation	SNPSDDTSCEDAEED CCCCCCCCCCCHHHH	23.62	23684622
328	Ubiquitination	ERTLQETKPEPPVNF HHHHHHCCCCCCCCH	46.78	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of PCMD2_MOUSE !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of PCMD2_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of PCMD2_MOUSE !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
Oops, there are no PPI records of PCMD2_MOUSE !!

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of PCMD2_MOUSE

Related Literatures of Post-Translational Modification